Edgardo Farinas

Associate Professor, Chemistry and Environmental Science

edgardo.t.farinas@njit.edu

386 Tiernan Hall (TIER)

About Me

Chair (07/01/2012-2017)

Associate Professor: New Jersey Institute of Technology (2010)

Assistant Professor: NJIT (2004-2010)

Postdoctoral Researcher: University of Texas at Austin (George Georgiou and Brett Iverson)

California Institute of Technology (Frances Arnold: Nobel Prize in Chemistry 2018)

Yale University (Lynn Regan)

PhD: University of California Santa Cruz (Pradip Mascharak)

Education

Ph.D.; University of California-Santa Cruz; Chemistry; 1997

B.S.; Loyola University Chicago; Chemistry; 1990

Website

https://sites.google.com/njit.edu/farinaslaboratory

2025 Spring Courses

CHE 790A - DOCT DISSERTATION & RES

CHEM 726 - INDEPENDENT STUDY II

EVSC 701B - MASTER'S THESIS

EVSC 725 - INDEPENDENT STUDY I

MTEN 491 - RESEARCH & INDEPENDENT STUDY I

EVSC 592 - GRADUATE WORK EXPERIENCE II

EVSC 790A - DOCTORAL DISSERTATION

CHEM 700B - MASTERS PROJECT

CHEM 725 - INDEPENDENT STUDY I

MTEN 701B - MASTERS THESIS

CHEM 475 - BIOCHEMISTRY LAB I

CHEM 790A - DOCTORAL DISSERTATION

EVSC 792B - PRE-DOCTORAL RESEARCH

MTEN 726 - INDEPENDENT STUDY II

PHEN 725 - INDEPENDENT STUDY

CHEM 391 - RESEARCH AND INDEPENDENT STUDY

MTEN 792 - PRE-DOCTORAL RESEARCH

CHEM 491 - RESEARCH & INDEP STUDY I

CHEM 492 - RESEARCH & INDEP STUDY

CHEM 590 - GRADUATE CO-OP WORK EXPER I

CHEM 701C - MASTERS THESIS

CHEM 792B - PRE-DOCTORAL RESEARCH

EVSC 700B - MASTER'S PROJECT

EVSC 726 - INDEPENDENT STUDY II

MTEN 700B - MASTER'S PROJECT

MTEN 725 - INDEPENDENT STUDY I

MTEN 790A - DOCT DISSERTATION & RES

CHEM 474 - BIOCHEMISTRY II

CHEM 701B - MASTERS THESIS

EVSC 591 - GRADUATE WORK EXPERIENCE I

EVSC 701C - MASTER'S THESIS

FRSC 491 - RESEARCH & INDEP STUDY I

MTEN 492 - RESRCH AND INDPENDENT STUDY II

Teaching Interests

Biochemistry

Past Courses

CHEM 125: GENERAL CHEMISTRY I

CHEM 244A: ORGANIC CHEMISTRY II LAB

CHEM 244A: ORGANIC CHEMISTRY II LABORATORY

CHEM 412: INORG REACTNS & PROCSSES

CHEM 473: BIOCHEMISTRY

CHEM 474: BIOCHEMISTRY II

CHEM 475: BIOCHEMISTRY LAB I

CHEM 673: BIOCHEMISTRY

Research Interests

Protein Engineering, Directed Evolution, Protein Display, Enzymes, Biotechnology

Other

“Applications of Bacillus subtilis Protein Display for Medicine, Catalysis, Environmental Remediation, and Protein Engineering”
Microorganisms, December 2023.

Journal Article

Indrani Gupta, Edgardo T. Farinas, Somenath Mitra. 2023. “Development of carbon nanotube-metal organic framework (MOF) hybrid antiviral microfiltration membrane.” Separation and Purification Technology, vol. 315, pp. 123766.

Indrani Gupta, Samar Azizighannad, Edgardo T. Farinas, Somenath Mitra. 2022. “Synergistic Antiviral Effects of Metal Oxides and Carbon Nanotubes.” International Journal of Molecular Science, vol. 23, no. 19, pp. 11967.

Indrani Gupta, Samar Azizighannad, Edgardo T. Farinas, Somenath Mitra. 2021. “Antiviral properties of select carbon nanostructures and their functionalized analogs. Materials Today Communications.” Materials Today Communications, vol. 29, pp. 102743.

Indrani Gupta, Joydeep Chakraborty, Sagar Roy, Edgardo T. Farinas, Somenath Mitra. 2021. “Synergistic Effects of Microwave Radiation and NanocarbonImmobilized Membranes in the Generation of Bacteria-Free Watervia Membrane Distillation.” Industrial and Engineering Chemistry Researcg, vol. 61, no. 3, pp. 1453-1463.

Silu Sheng, Edgardo T. Farinas. 2021. “Laccase and Its Mutant Displayed on the Bacillus subtilis Spore Coat for Oxidation of Phenolic Compounds in Organic Solvents.” Cataylsis, vol. 11, pp. 606.

Indrani Chakraborty, Joydeep Chakraborty, Edgardo T Farinas, Somenath Mitra. 2020. “Nanocarbon immobilized membranes for generating bacteria and endotoxin free water via membrane distillation.” Separation and Purification Technology, vol. 259, pp. Joydeep.

Joydeep T. Chakraborty, Natalia S Nereria, Xu Zhang, Pradeep R Reddy, Michal Szostak, Edgardo T Farinas, Frank Jordan. 2019. “Engineering 2-oxoglutarate dehydrogenase to a 2-oxoaliphatic dehydrogenase complex by optimizing consecutive components.” AIChE Journal, pp. e16769.

Joydeep Chakraborty, Natalia S. Nermeria, Edgardo T. Farinas, Frank Jordan. 2018. “Catalysis of transthioacylation in the active centers of dihydrolipoamide acyltransferase components of 2-oxo acid dehydrogenase complex.” FEBS Open Bio , vol. 8, no. 6, pp. 880-896.

Silu . Sheng, Han Jia, Sidney Topiol, Edgardo T Farinas. 2017. “Engineering CotA Laccase for Acidic pH Stability using Bacillus subtilis Spore Display.” J. Microbiol. Biotechnol, vol. 27, pp. 507-513.

Hetalben Patel, Da Jeong Shim, Edgardo T. Farinas, Frank Jordan. “Investigation of the donor and acceptor range for chiral carboligation catalyzed by the E1 component of the 2-oxoglutarate dehydrogenase complex.” Journal of Molecular Catalysis B: Enzymatic, vol. 98, pp. 42-45.

Da Jeong Shim, Natalia S Nemeria, Anand Balakrishman, Hetalban Patel, Jaeyoung Song, Frank Jordan, Edgardo T. Farinas. 2011. “Assignment of Function to Histidines 260 and 298 by Engineering the E1 Component of the Escherichia coli 2-Oxoglutarate Dehydrogenase Complex; Substitutions That Lead to Acceptance of Substrates Lacking the 5-Carboxyl Group.” Biochemistry, vol. 50, no. 35, pp. 7705-7709.

Nirupama Gupta, Edgardo T. Farinas. 2010. “Directed evolution of CotA laccase for increased substrate specificity using Bacillus subtilis spores.” Protein Engineering, Design & Selection/Oxford Journals, vol. 23, no. 8, pp. 679-682.

Nirupama Gupta, Frederick S Lee, Edgardo T. Farinas. 2009. “Laboratory Evolution of Laccase for Substrate Specificity.” Journal of Molecular Catalysis B: Enzymatic, vol. 62, no. 3-4, pp. 230-234.

Conference Proceeding

“Molecular Augmented Reality for Design and Engineering (MADE): Effectiveness of AR Models on Discovery, Learning, and Education”
Springer Nature Switzerland AG, 2020.