Jonathan Grasman

Jonathan Grasman, PhD is an assistant professor in the department of biomedical engineering at New Jersey Institute of Technology. Professor Grasman received his bachelor’s degree with high honors from the University of Pittsburgh and his Ph.D. in biomedical engineering from Worcester Polytechnic Institute. His doctoral research with Dr. George Pins focused on developing novel methods to design tunable structural and biochemical properties of fibrin microthreads in the context of skeletal muscle regeneration as an NRSA predoctoral fellow. He was subsequently an NRSA postdoctoral fellow in the biomedical engineering department at Tufts University, where he worked with Dr. David Kaplan on developing tissue systems to study the co-development of vascular and neural networks. His research interests include tissue engineering and biomaterials development and customization, particularly focused in skeletal muscle tissues and the study of innervation and vascularization.

Ph.D.; Worcester Polytechnic Institute; Biomedical Engineering; 2015

B.S.; University of Pittsburgh-Pittsburgh Campus; Bioengineering; 2008

https://centers.njit.edu/timm/

Our research objective is to better elucidate the mechanisms behind tissue innervation and soft tissue reconstruction. Specifically, we focus on fabricating tissue systems from a variety of biopolymers to generate neurovascular and skeletal muscle tissue mimetics to enhance regeneration and innervation in incidents of traumatic injury, neuropathy, or genetic disorders both in in vitro systems and in vivo.
-Tissue Engineering
-Biomaterials-tissue/cell interactions
-3D tissue models
-Tissue innervation
-Neurovascular interactions
-Soft tissue regeneration and reconstruction
-Skeletal muscle tissue engineering
-Neural tissue engineering
-Nervous system injury and repair
-Stem cells and cellular reprogramming
-Biopolymers
-Volumetric muscle loss

Angiogenic peptides for aligned vasculature development for muscle regeneration
Develop a self-assembling angiogenic peptide that can be injected into a collagen scaffold as an implant to induce volumetric muscle regeneration.

Novel Cupping peptide therapy for vascular disease
Develop a non-invasive therapy for patients peripheral artery disease.