Education
Ph.D.; Johns Hopkins University; Electrical And Computer Engineering; 2011
M.S.; Tsinghua University; Physics; 2007
B.A.; Tsinghua University; Electronic Science And Technology; 2005
2026 Fall Courses
ENGR 310 - CO-OP WORK EXPERIENCE I
ECE 792B - PRE-DOCTORAL RESEARCH
ENGR 410 - CO-OP WORK EXPERIENCE II
ECE 416 - ELECT & COMP ENGNR PROJ II
ECE 701B - MASTER'S THESIS
ECE 725 - INDEPENDENT STUDY I
ECE 700B - MASTER'S PROJECT
Past Courses
ECE 416: ELECT & COMP ENGNR PROJ II - HONORS
ECE 416: ELECTRICAL AND COMPUTER ENGINEERING PROJECT II
ECE 601: LINEAR SYSTEMS
Journal Article
Rupak Bhakta, Gizem Celebi Torabfam, Yuanwei Zhang, Cristiano Luis Dias, Xuan Liu. 2026. "Modulated Doppler phase microscopy for dynamic imaging with subcellular resolution." Biomed. Opt. Express, vol. 17, no. 4, pp. 1846--1858.
Rupak Bhakta, Gizem Celebi Torabfam, Yuanwei Zhang, Cristiano Luis Dias, Xuan Liu. 2026. "Modulated Doppler phase microscopy for dynamic imaging with subcellular resolution." Biomedical Optics Express, vol. 17.
Xuan Liu, Rupak Bhakta, Emily Kryvorutsky, Yuanwei Zhang. 2025. "Imaging cells and nanoparticles using modulated optically computed phase microscopy." Scientific Reports, vol. 15, no. 1, pp. 3157.
Don Bonifacio, Laterriean M. Minaya, Xuemei Chen, Yuanwei Zhang, Xuan Liu. 2025. "Phase-augmented deep learning for cell segmentation in wrapped quantitative phase images." Biomed. Opt. Express, vol. 16, no. 7, pp. 2835--2846.
Zhaoxiong Wan, Shupei Yu, Qi Wang, Karthik Sambath, Roshena Harty, Xiangshan Liu, Hao Chen, Chen Wang, Xuan Liu, Yuanwei Zhang. 2023. "Far-red BODIPY-based oxime esters: photo-uncaging and drug delivery." Journal of Materials Chemistry B, vol. 11, no. 41, pp. 9889--9893.
Xuan Liu, Yuwei Liu, Shupei Yu, Yuanwei Zhang. 2023. "Complex optically computed phase microscopy for label-free sub-cellular imaging." Opt. Continuum, vol. 2, no. 4, pp. 793--800.
Yuwei Liu, Shupei Yu, Yuanwei Zhang, Xuan Liu. 2023. "Label-free full-field Doppler phase microscopy based on optical computation." Biomed. Opt. Express, vol. 14, no. 1, pp. 441--452.
Xuan Liu, Samantha Ouellette, Marielle Jamgochian, Yuwei Liu, Barar Rao. 2023. "One-class machine learning classification of skin tissue based on manually scanned optical coherence tomography imaging." Scientific Reports, vol. 13, no. 1, pp. 867.
Zhaoxiong Wan, Shupei Yu, Qi Wang, John Tobia, Hao Chen, Zhanjun Li, Xuan Liu, Yuanwei Zhang. 2022. "A BODIPY-Based Far-Red-Absorbing Fluorescent Probe for Hypochlorous Acid Imaging." ChemPhotoChem, pp. e202100250.
Xingyu Zhou, Darlene In, Xinchang Xiong, Kunze Yang, Xing Chen, Heather McCune Bruhn, Xuan Liu, Yi Yang. 2022. "A Note on Macroscopic Optical Coherence Tomography Imaging Enabled 3D Scanning for Museum and Cultural Heritage Applications." Journal of the American Institute for Conservation, vol. 0, no. 0, pp. 1-10.
Xuan Liu, Yuwei Liu, Zhaoxiong Wan, Arun Kumar Gunasekar, Yuanwei Zhang. 2022. "Quantitative dynamic cellular imaging based on 3D unwrapped optically computed phase microscopy." Appl. Opt., vol. 61, no. 27, pp. 7999--8005.
Xuan Liu, Zhaoxiong Wan, Yuanwei Zhang, Yuwei Liu. 2022. "Optically computed phase microscopy for quantitative dynamic imaging of label-free cells and nanoparticles." Biomed. Opt. Express, vol. 13, no. 1, pp. 514--524.
Yahui Wang, Xuan Liu. 2021. "Line field Fourier domain optical coherence tomography based on a spatial light modulator." Applied Optics, vol. 60, no. 4, pp. 985--992.
Mu Qiao, Yangyang Sun, Jiawei Ma, Ziyi Meng, Xuan Liu, Xin Yuan. 2021. "Snapshot Coherence Tomographic Imaging." IEEE Transactions on Computational Imaging, vol. 7, pp. 624-637.
Mu Qiao, Xuan Liu, Xin Yuan. 2021. "Snapshot temporal compressive microscopy using an iterative algorithm with untrained neural networks." Opt. Lett, vol. 2.
Xuan Liu, Nadiya Chuchvara, Yuwei Liu, Babar Rao. 2021. "Real-time deep learning assisted skin layer delineation in dermal optical coherence tomography." OSA Continuum, vol. 4, no. 7, pp. 2008--2023.
Nadiya Chuchvara, Babar Rao, Xuan Liu. 2021. "Manually scanned single fiber optical coherence tomography for skin cancer characterization." Scientific Reports, vol. 11, no. 1, pp. 15570.
Yuwei Liu, Roberto Adamson, Mark Galan, Basil Hubbi, Xuan Liu. 2021. "Quantitative characterization of human breast tissue based on deep learning segmentation of 3D optical coherence tomography images." Biomed. Opt. Express, vol. 12, no. 5, pp. 2647--2660.
Mu Qiao, Xuan Liu, Xin Yuan. 2020. "Snapshot spatial--temporal compressive imaging." Optics letters, vol. 45, no. 7, pp. 1659--1662.
Xingyu Zhou, Darlene In, Xing Chen, Heather McCune Bruhn, Xuan Liu, Yi Yang. 2020. "Spectral 3D reconstruction of impressionist oil paintings based on macroscopic OCT imaging." Applied Optics, vol. 59, no. 15, pp. 4733--4738.
Yahui Wang, Qi Kang, Yuanwei Zhang, Xuan Liu. 2020. "Optically computed optical coherence tomography for volumetric imaging." Optics Letters, vol. 45, no. 7, pp. 1675-1678.
Xuan Liu, Basil Hubbi, Xianlian A. Zhou. 2019. "Spatial coordinate corrected motion tracking for optical coherence elastography." Biomedical Optics Express, vol. 10, no. 12, pp. 6160-6171.
Xuan Liu, Farzana Zaki, Dylan Renaud. 2018. "Assessment and removal of additive noise in a complex optical coherence tomography signal based on Doppler variation analysis." Applied optics, vol. 57, no. 11, pp. 2873--2880.
Xuan Liu, Farzana Zaki, Yahui Wang. 2018. "Quantitative optical coherence elastography for robust stiffness assessment." Applied Sciences, vol. 8, no. 8, pp. 1255.
Xuan Liu, Farzana R Zaki, Haokun Wu, Chizhong Wang, Yahui Wang. 2018. "Temporally and spatially adaptive Doppler analysis for robust handheld optical coherence elastography." Biomedical optics express, vol. 9, no. 7, pp. 3335--3353.
Xuan Liu, Kerri Lee Chintersingh, Mirko Schoenitz, Edward L. Dreyzin. 2018. "Reactive composite boron - Magnesium powders prepared by mechanical milling." Journal of Propulsion and Power, vol. 34, no. 3, pp. 787-794.
Hao Su, Iulian I Iordachita, Junichi Tokuda, Nobuhiko Hata, Xuan Liu, Reza Seifabadi, Sheng Xu, Bradford Wood, Gregory S Fischer. 2017. "Fiber Optic Force Sensors for MRI-Guided Interventions and Rehabilitation: A Review." IEEE sensors journal, vol. 17, no. 7, pp. 1952.
Farzana Zaki, Yahui Wang, Hao Su, Xin Yuan, Xuan Liu. 2017. "Noise adaptive wavelet thresholding for speckle noise removal in optical coherence tomography." Biomedical optics express, vol. 8, no. 5, pp. 2720--2731.
Xuan Liu, Farzana Zaki, Yahui Wang, Qiongdan Huang, Xin Mei, Jiangjun Wang. 2017. "Secure fingerprint identification based on structural and microangiographic optical coherence tomography." Applied optics, vol. 56, no. 8, pp. 2255--2259.
T Wu, A J Dufford, L J Egan, M A Mackie, C Chen, C Yuan, C Chen, X Li , Xuan Liu, P R Hof, J Fan. 2017. "Hick-Hyman Law is Mediated by the Cognitive Control Network in the Brain.." Cerebral cortex (New York, N.Y. : 1991), pp. 1-16.
Farzana Zaki, Isabella Hou, Denver Cooper, Divya Patel, Yi Yang, Xuan Liu. 2016. "High-definition optical coherence tomography imaging for noninvasive examination of heritage works." Applied optics, vol. 55, no. 36, pp. 10313--10317.
Xuan Liu, Lijun Zhang, Mitchell Kirby, Richard Becker, Shaohai Qi, Feng Zhao. 2016. "Iterative l 1-min algorithm for fixed pattern noise removal in fiber-bundle-based endoscopic imaging." JOSA A, vol. 33, no. 4, pp. 630--636.
Yi Qiu, Farzana R Zaki, Namas Chandra, Shawn A. Chester, Xuan Liu. 2016. "Nonlinear characterization of elasticity using quantitative optical coherence elastography." Biomedical optics express, vol. 7, no. 11, pp. 4702--4710.
Yi Qiu, Yahui Wang, Yiqing Xu, Namas Chandra, James Haorah, Basil Hubbi, Bryan J. Pfister, Xuan Liu. 2016. "Quantitative optical coherence elastography based on fiber-optic probe for in situ measurement of tissue mechanical properties." Biomedical optics express, vol. 7, no. 2, pp. 688--700.
Y Qiu, Y Wang, KD Belfield, Xuan Liu. 2016. "Ultrathin lensed fiber-optic probe for optical coherence tomography." Biomedical optics express, vol. 7, no. 6, pp. 2154--2162.
Yi Qui, Farzana Zaki, Namas Chandra, Shawn A. Chester, Xuan Liu. 2016. "Nonlinear characterization of elasticity using quantitative optical coherence elastography." Biomedical Optics Express, vol. 7, no. 11, pp. 4702-4710.
Xiling Yue, Alma R Morales, Grace W Githaiga, Adam W Woodward, Simon Tang, Junko Sawada, Masanobu Komatsu, Xuan Liu, Kevin D. Belfield. 2015. "RGD-conjugated two-photon absorbing near-IR emitting fluorescent probes for tumor vasculature imaging." Organic \& biomolecular chemistry, vol. 13, no. 43, pp. 10716--10725.
Yuewen Wang, Yahui Wang, Ali N. Akansu, Kevin D. Belfield, Basil Hubbi, Xuan Liu. 2015. "Robust motion tracking based on adaptive speckle decorrelation analysis of OCT signal." Biomedical optics express, vol. 6, no. 11, pp. 4302--4316.
Jin U Kang, Xuan Liu. 2014. "Fiber optic microscopy." Optical Nanoscopy and Novel Microscopy Techniques, pp. 179.
Xuan Liu, Jin U Kang. 2014. "Iterative sparse reconstruction of spectral domain OCT signal." Chinese Optics Letters, vol. 12, no. 5, pp. 051701.
Xuan Liu, Mitchell Kirby, Feng Zhao. 2014. "Motion analysis and removal in intensity variation based OCT angiography." Biomedical optics express, vol. 5, no. 11, pp. 3833--3847.
Xuan Liu, Jin U Kang. 2013. "Optimization of an angled fiber probe for common-path optical coherence tomography." Optics letters, vol. 38, no. 15, pp. 2660--2662.
Xuan Liu, Yong Huang, Jessica C Ramella-Roman, Scott A Mathews, Jin U Kang. 2013. "Quantitative transverse flow measurement using optical coherence tomography speckle decorrelation analysis." Optics letters, vol. 38, no. 5, pp. 805--807.
Xuan Liu, Jessica C Ramella-Roman, Yong Huang, Yuan Guo, Jin U Kang. 2013. "Robust spectral-domain optical coherence tomography speckle model and its cross-correlation coefficient analysis." JOSA A, vol. 30, no. 1, pp. 51--59.
Xuan Liu, Yong Huang, Jin U Kang. 2012. "Distortion-free freehand-scanning OCT implemented with real-time scanning speed variance correction." Optics express, vol. 20, no. 15, pp. 16567--16583.
Xuan Liu, Iulian I Iordachita, Xingchi He, Russell H Taylor, Jin U Kang. 2012. "Miniature fiber-optic force sensor based on low-coherence Fabry-P\'erot interferometry for vitreoretinal microsurgery." Biomedical Optics Express, vol. 3, no. 5, pp. 1062--1076.
Yong Huang, Xuan Liu, Cheol Song, Jin U Kang. 2012. "Motion-compensated hand-held common-path Fourier-domain optical coherence tomography probe for image-guided intervention." Biomedical optics express, vol. 3, no. 12, pp. 3105.
Yong Huang, Xuan Liu, Jin U Kang. 2012. "Real-time 3D and 4D Fourier domain Doppler optical coherence tomography based on dual graphics processing units." Biomedical Optics Express, vol. 3, no. 9, pp. 2162--2174.
Xuan Liu, Yong Huang, Jin Ung Kang. 2011. "Dark-field illuminated reflectance fiber bundle endoscopic microscope." Journal of biomedical optics, vol. 16, no. 4, pp. 046003.
Xuan Liu, Kang Zhang, Yong Huang, Jin U Kang. 2011. "Spectroscopic-speckle variance OCT for microvasculature detection and analysis." Biomedical optics express, vol. 2, no. 11, pp. 2995--3009.
Jae-Ho Han, Xuan Liu, Jin U Kang, Chul Gyu Song, others. 2010. "?? FD-CPOCT ??????????????." Chinese Optics Letters, vol. 8, no. 2, pp. 167.
Jin-U Kang, Jae-Ho Han, Xuan Liu, Kang Zhang. 2010. "Common-path optical coherence tomography for biomedical imaging and sensing." Journal of the Optical Society of Korea, vol. 14, no. 1, pp. 1--13.
Xuan Liu, Jin U Kang. 2010. "Compressive SD-OCT: the application of compressed sensing in spectral domain optical coherence tomography." Optics express, vol. 18, no. 21, pp. 22010--22019.
Xuan Liu, Jin U Kang. 2010. "Depth-resolved blood oxygen saturation assessment using spectroscopic common-path Fourier domain optical coherence tomography." IEEE Transactions on Biomedical Engineering, vol. 57, no. 10, pp. 2572--2575.
Jin U Kang, Jae-Ho Han, Xuan Liu, Kang Zhang, Chul Gyu Song, Peter Gehlbach. 2010. "Endoscopic functional Fourier domain common-path optical coherence tomography for microsurgery." IEEE Journal of Selected Topics in Quantum Electronics, vol. 16, no. 4, pp. 781--792.
Jae-Ho Han, Xuan Liu, Jin U Kang, Chul Gyu Song. 2010. "High-resolution subsurface articular cartilage imaging based on Fourier-domain common-path optical coherence tomography." Chinese Optics Letters, vol. 8, no. 2, pp. 167--169.
Xuan Liu, Marcin Balicki, Russell H Taylor, Jin U Kang. 2010. "Towards automatic calibration of Fourier-Domain OCT for robot-assisted vitreoretinal surgery." Optics express, vol. 18, no. 23, pp. 24331--24343.
Jae-Ho Han, Xuan Liu, Jin U Kang, Chul Gyu Song, others. 2010. "基于 FD-CPOCT 的高分辨率关节软骨次表面成像." Chinese Optics Letters, vol. 8, no. 2, pp. 167.
J-H Han, Xuan Liu, CG Song, JU Kang. 2009. "Common path optical coherence tomography with fibre bundle probe." Electronics letters, vol. 45, no. 22, pp. 1110--1112.
Xuan Liu, Xiaolu Li, Do-Hyun Kim, Ilko Ilev, Jin U Kang. 2008. "Fiber-optic Fourier-domain common-path OCT." Chinese Optics Letters, vol. 6, no. 12, pp. 899--901.
Xiaolu Li, Jae-Ho Han, Xuan Liu, Jin U Kang. 2008. "Signal-to-noise ratio analysis of all-fiber common-path optical coherence tomography." Applied optics, vol. 47, no. 27, pp. 4833--4840.
Xuan Liu, Xiaolu Li, Do-Hyun Kim, Ilko Ilev, Jin U Kang, others. 2008. "光纤频域共路 OCT." Chinese Optics Letters, vol. 6, no. 12, pp. 899.
Conference Proceeding
"Optically computed phase microscopy to assess cellular uptake of lipid nanoparticles"
Conference on Lasers and Electro-Optics, 2022.
Conference on Lasers and Electro-Optics, 2022.
"Digital Staining of Reflectance Confocal Microscopy Images: A Proof of Concept"
Biophotonics Congress 2021, 2021.
Biophotonics Congress 2021, 2021.
"OCT Based Scanning System to enable 3D Viewing, Sharing and Printing of Artworks"
OSA Imaging and Applied Optics Congress 2021 (3D, COSI, DH, ISA, pcAOP), 2021.
OSA Imaging and Applied Optics Congress 2021 (3D, COSI, DH, ISA, pcAOP), 2021.
"Optical computation for complex OCT"
2020.
2020.
"Single fiber OCT imager for breast tissue classification based on deep learning"
2020.
2020.
"Adaptive Doppler analysis for robust handheld optical coherence elastography"
2019.
2019.
"Intelligent optical computation for online optical signal processing"
2019.
2019.
"OCE quantification of Poisson's ratio through 2D speckle tracking"
2019.
2019.
"Snapshot optical coherence tomography"
2019.
2019.
"Compressive OCT based on spectral domain random encoding"
2018.
2018.
"Wavelet tree structure based speckle noise removal for optical coherence tomography"
2018.
2018.
"Adaptive Wavelet Thresholding for Optical Coherence Tomography Image Denoising"
2017.
2017.
"Characterization of nonlinear elasticity for biological tissue using quantitative optical coherence elastography"
2017.
2017.
"Interactive virtual optical laboratories"
2017.
2017.
"Optical coherence tomography for non-invasive examination and conservation of cultural heritage objects"
2017.
2017.
"Robust stiffness quantification using quantitative optical coherence elastography"
2017.
2017.
"Depth resolved optical coherence elastography based on fiber-optic probe with integrated Fabry-Perot force sensor"
2016.
2016.
"Entropy analysis of OCT signal for automatic tissue characterization"
2016.
2016.
"Composite B·Mg powders prepared by mechanical milling"
January (1st Quarter/Winter), 2016.
January (1st Quarter/Winter), 2016.
"Dark-field illuminated fiber bundle endoscopy with iterative l 1-min image reconstruction for honeycomb pattern removal"
2015.
2015.
"Dark-field illuminated fiber bundle endoscopy with iterative l1-min image reconstruction for honeycomb pattern removal"
2015.
2015.
"Motion analysis and removal in intensity variation based OCT microangiography"
2015.
2015.
"Reference optimization for a common-path optical coherence tomography probe using angle polishing"
2014.
2014.
"Tracking both magnitude and direction of 2D transverse motion with optical coherence tomography"
2014.
2014.
"Freehand OCT with real-time lateral motion tracking"
2013.
2013.
"Improvement of optical coherence tomography using active handheld micromanipulator in vitreoretinal surgery"
2013.
2013.
"Motion-compensated hand-held common-path Fourier-domain optical coherence tomography probe for image-guided intervention"
2013.
2013.
"Optical coherence tomography scanning with a handheld vitreoretinal micromanipulator"
2012.
2012.
"Automatic online spectral calibration of Fourier-domain OCT for robotic surgery"
2011.
2011.
"Sparse OCT: Optimizing compressed sensing in spectral domain optical coherence tomography"
2011.
2011.
"High resolution hemoglobin oxygen saturation level imaging using Morlet wavelet transformed spectroscopic Optical Coherence Tomography"
2010.
2010.
"Internal limiting membrane layer visualization and vitreoretinal surgery guidance using a common-path OCT integrated microsurgical tool"
2010.
2010.
"Progress toward inexpensive endoscopic high-resolution common-path OCT"
2010.
2010.
"Fourier domain common-path optical coherence tomography with a conduit fiber bundle probe"
2009.
2009.
"Functional common-path Fourier-domain OCT for hemoglobin oxygen saturation imaging"
2009.
2009.
Other
"Dark field endoscopic microscope"
March, 2020.
March, 2020.
"High definition optical coherence tomography imaging for non-invasive examination of heritage works"
June, 2018.
June, 2018.
"Optical coherence tomography systems and methods with magnitude and direction tracking of transverse motion"
November, 2016.
November, 2016.
"Interferometric force sensor for surgical instruments"
January (1st Quarter/Winter), 2016.
January (1st Quarter/Winter), 2016.
"Lateral distortion corrected optical coherence tomography system"
January (1st Quarter/Winter), 2016.
January (1st Quarter/Winter), 2016.
"Distortion corrected optical coherence tomography system"
December, 2015.
December, 2015.
"Durable single mode fiber probe with optimized reference reflectivity"
November, 2015.
November, 2015.
"System and method for assessing the flow of a fluid"
February, 2015.
February, 2015.
"Automatic calibration of fourier-domain optical coherence tomography systems"
December, 2014.
December, 2014.
"Dark field endoscopic microscope"
November, 2012.
November, 2012.
"Functional Fourier-domain optical coherence tomography for guiding vitreoretinal surgery"
The Johns Hopkins University, 2011.
The Johns Hopkins University, 2011.
Manuscript
"Quantitative optical coherence elastography based on fiber-optic probe with integrated Fabry-Perot force sensor"
Biomedical Optics Express.
Biomedical Optics Express.
"Robust motion tracking based on adaptive speckle decorrelation analysis of OCT signal"
Biomedical Optics Express, September, 2015.
Biomedical Optics Express, September, 2015.
"Motion analysis and removal in intensity variation based OCT angiography"
Biomedical Optics Express, September, 2014.
Biomedical Optics Express, September, 2014.
Chapter
Xuan Liu, Jin U Kang. "Fiber optic microscopy." pp. 190--209. CRC Press, 2014.