Dr. Genoa Warner an Assistant Professor in the Department of Chemistry and Environmental Science in the College of Science and Liberal Arts. Her laboratory, the Endocrine Disruption and Chemical Biology Laboratory (EDC Lab), uses chemical tools to investigate the toxicity and mechanisms of endocrine disrupting chemicals in biological systems. She completed postdoctoral training in reproductive toxicology in the Department of Comparative Biosciences at the University of Illinois at Urbana-Champaign and received her PhD from Carnegie Mellon University in the Department of Chemistry, where she developed small molecule catalysts to degrade micropollutants in water.

Ph.D. ; Carnegie Mellon University ; Chemistry ; 2017

M.S. ; Carnegie Mellon University ; Chemistry ; 2016

B.S. ; Yale University ; Chemistry ; 2012

http://www.genoawarner.com

CHEM 391 - RESEARCH AND INDEPENDENT STUDY

CHEM 590 - GRADUATE CO-OP WORK EXPER I

CHEM 726 - INDEPENDENT STUDY II

EVSC 700B - MASTER'S PROJECT

CHEM 492 - RESEARCH & INDEP STUDY

CHEM 725 - INDEPENDENT STUDY I

CHEM 790A - DOCTORAL DISSERTATION

CHEM 792B - PRE-DOCTORAL RESEARCH

EVSC 591 - GRADUATE WORK EXPERIENCE I

EVSC 592 - GRADUATE WORK EXPERIENCE II

EVSC 616 - TOXICOLOGY

EVSC 790A - DOCTORAL DISSERTATION

EVSC 726 - INDEPENDENT STUDY II

EVSC 792B - PRE-DOCTORAL RESEARCH

CHEM 591 - GRADUATE CO-OP WORK EXPER II

CHEM 701B - MASTERS THESIS

EVSC 701C - MASTER'S THESIS

EVSC 725 - INDEPENDENT STUDY I

CHEM 491 - RESEARCH & INDEP STUDY I

CHEM 701C - MASTERS THESIS

EVSC 701B - MASTER'S THESIS

FRSC 491 - RESEARCH & INDEP STUDY I

CHEM 700B - MASTERS PROJECT

toxicology, green and sustainable chemistry

The Laboratory of Endocrine Disruption & Chemical Biology (EDC Lab) uses chemical tools to investigate the toxicity and mechanisms of endocrine disrupting chemicals in biological systems. Endocrine disrupting chemicals are chemicals that interfere in any way with the production, distribution, or action of hormones in the body. Many endocrine disrupting chemicals are hormone mimics. Human are exposed during daily life to endocrine disrupting chemicals, which include ingredients in pesticides, personal care products, pharmaceuticals, and consumer products.

We study the effects of endocrine disrupting chemicals on the female reproductive tract, particularly the ovary, using a mouse model. The ovary is vital for female reproductive health. It is responsible for production of hormones such as estrogen and progesterone as well as development and release of oocytes. Disruption of oocyte maturation, ovulation, or hormone production can result in infertility, premature menopause, and other hormone-related diseases.

Our research bridges reproductive biology, toxicology, and sustainable chemistry to study the mechanisms by which environmental chemicals act as endocrine disruptors. We use chemical biology techniques to identify the molecular targets of endocrine disrupting chemicals. Understanding how endocrine disrupting chemicals act in the body is important for the development of safer chemicals and for developing novel therapeutics to prevent damage to sensitive reproductive organs.

Abdul Qadeer, Muhammad Anis, Genoa R Warner, Courtney Potts, Georgios Giovanoulis, Samia Nasr, Denisse Archundia, Qinghuan Zhang, Zeeshan Ajmal, Anthony C. Tweedale, Wang Kun, Pengfei Wang, Ren Haoyu, Xia Jiang, Wang Shuhang. 2024. "Global environmental and toxicological data of emerging plasticizers: current knowledge, regrettable substitution dilemma, green solution and future perspectives." Green Chemistry , vol. 26 , no. 10 , pp. 5635-5683.

Genoa R Warner, Zhong Li, Jodi A. Flaws, Rebecca Smith. 2024. "Year-to-year variation in phthalate metabolites in the Midlife Women’s Health Study." Journal of Exposure Science & Environmental Epidemiology , vol. 34 , no. 4 , pp. 610-619.

Genoa R Warner, Vasiliki E. Mourikes, Alison M. Neff, Emily Brehm, Jodi A. Flaws. 2020. "Mechanisms of action of agrochemicals acting as endocrine disrupting chemicals." Molecular and Cellular Endocrinology , vol. 502 , pp. 110680.