Mesut Sahin
Mesut Sahin
Professor, Bio-Medical Engineering
617 Fenster Hall (FENS)
About Me
Mesut Sahin received the B.S. degree in electrical engineering from Istanbul Technical University, Turkey in 1986 and the M.S. and Ph.D. degrees in biomedical engineering from Case Western Reserve University, Cleveland, Ohio in 1993 and 1998. He joined Louisiana Tech University, Ruston, LA as an Assistant Professor of Biomedical Engineering in 2001. He has been on the faculty of Biomedical Engineering at New Jersey Institute of Technology, Newark, NJ since Fall 2005 with promotion to Associate Professor in 2009 and Full Professor in 2015. His current research interests include Neuromodulation of the cerebellum using transcranial AC Stimulation (tACS) and Focused Ultrasound (FUS). He has developed floating microstimulators for the spinal cord (FLAMES) and studied the activity of the descending pathways of the spinal cord in correlation to the forelimb function in animal models. He has authored more than 100 peer-reviewed publications, acquired three patents, and written a textbook on bioinstrumentation. He has mentored 17 PhD and 23 Master’s theses. Mesut Sahin is a Senior Member of IEEE/EMBS since 2006.
Education
Ph.D.; Case Western Reserve University; Biomedical Engineering; 1998
M.S.; Case Western Reserve University; Biomedical Engineering; 1993
B.S.; Istanbul Technical University; Electrical Engineering; 1986
M.S.; Case Western Reserve University; Biomedical Engineering; 1993
B.S.; Istanbul Technical University; Electrical Engineering; 1986
Website
2025 Spring Courses
BME 701B - MASTER'S THESIS
BME 493 - HONORS RESEARCH THESIS I
BME 491 - RESEARCH & INDEPENDENT STUDY I
BME 492 - RESEARCH & INDPNDNT STUDY II
BME 790A - DOCTORAL DISSERTATION
BME 792 - PRE-DOCTORAL RESEARCH
BME 494 - HONORS RESEARCH THESIS II
BME 493 - HONORS RESEARCH THESIS I
BME 491 - RESEARCH & INDEPENDENT STUDY I
BME 492 - RESEARCH & INDPNDNT STUDY II
BME 790A - DOCTORAL DISSERTATION
BME 792 - PRE-DOCTORAL RESEARCH
BME 494 - HONORS RESEARCH THESIS II
Teaching Interests
Biomedical Instrumentation
Neuromodulation
Neuromodulation
Past Courses
BME 301: ELECTRICAL FUNDAMENTALS OF BIOMEDICAL ENGINEERING
BME 301: INTRO BIOMEDICAL ENG I HONORS
BME 301: INTRO BIOMEDICAL ENGINEERING I
BME 301: INTRO BIOMEDICAL ENGINRNG HONOR
BME 310: BIOMEDICAL COMPUTING
BME 386: BIOINSTRUMENTATION LABORATORY
BME 386: BIOSENSOR AND DATA ACQUISITION LAB
BME 498: ST:BIO INSTRUMENTATION LAB
BME 687: MEDICAL INSTRUMENTATION
BME 698: ST: NEURAL PROSTHETICS
BME 698: ST: SPECIAL PROJECTS
BME 788: ST: NEUROMODULATION
BME 791: GRADUATE SEMINAR
BME 301: INTRO BIOMEDICAL ENG I HONORS
BME 301: INTRO BIOMEDICAL ENGINEERING I
BME 301: INTRO BIOMEDICAL ENGINRNG HONOR
BME 310: BIOMEDICAL COMPUTING
BME 386: BIOINSTRUMENTATION LABORATORY
BME 386: BIOSENSOR AND DATA ACQUISITION LAB
BME 498: ST:BIO INSTRUMENTATION LAB
BME 687: MEDICAL INSTRUMENTATION
BME 698: ST: NEURAL PROSTHETICS
BME 698: ST: SPECIAL PROJECTS
BME 788: ST: NEUROMODULATION
BME 791: GRADUATE SEMINAR
Research Interests
• Neuromodulation of the Cerebellum using Focused Ultrasound and tACS
• Stimulation of Neural Tissue with Optically Activated MicroStimulators
• Carbon Fiber Electrode Array and Bundles
• Spinal Cord - Computer Interface
• Stimulation of Neural Tissue with Optically Activated MicroStimulators
• Carbon Fiber Electrode Array and Bundles
• Spinal Cord - Computer Interface
Conference Abstract
“ID: 341296 Transient Effects in Transsynaptic Modulation of the Cerebellar Nuclear Cells during theta-gamma Stimulation”
October (4th Quarter/Autumn) 2024.
October (4th Quarter/Autumn) 2024.
Other
“Pathway to recovery: understanding the plastic changes in neural circuits leading to recovery”
April (2nd Quarter/Spring) 2024.
April (2nd Quarter/Spring) 2024.
Journal Article
Mesut Sahin. 2024. “Sensorimotor content of multi-unit activity recorded in the paramedian lobule of the cerebellum using carbon fiber microelectrode arrays.” .
Mesut Sahin, Qi Kang. 2023. “Transsynaptic entrainment of cerebellar nuclear cells by alternating currents in a frequency dependent manner.” Frontiers in Neuroscience.
Mesut Sahin, Saikat Pal, Ozan Cakmak. 2023. “Improving the stimulation selectivity in human cochlea by strategically choosing the current return electrode.” Frontiers in Audiology and Otology, vol. 1.
Mesut Sahin. 2023. “Modulation of cerebellar cortical, cerebellar nuclear and vestibular nuclear activity using alternating electric currents.” .
Bemin Ghobreal, Farzan Nadim, Mesut Sahin. 2022. “Selective neural stimulation by leveraging electrophysiological differentiation and using pre-pulsing and non-rectangular waveforms.” Journal of Computational Neuroscience.
Mesut Sahin, Qi Kang. 2023. “Transsynaptic entrainment of cerebellar nuclear cells by alternating currents in a frequency dependent manner.” Frontiers in Neuroscience.
Mesut Sahin, Saikat Pal, Ozan Cakmak. 2023. “Improving the stimulation selectivity in human cochlea by strategically choosing the current return electrode.” Frontiers in Audiology and Otology, vol. 1.
Mesut Sahin. 2023. “Modulation of cerebellar cortical, cerebellar nuclear and vestibular nuclear activity using alternating electric currents.” .
Bemin Ghobreal, Farzan Nadim, Mesut Sahin. 2022. “Selective neural stimulation by leveraging electrophysiological differentiation and using pre-pulsing and non-rectangular waveforms.” Journal of Computational Neuroscience.
SHOW MORE
Manan Sethia, Mesut Sahin. 2022. “The size of via holes influence the amplitude and selectivity of neural signals in Micro-ECoG arrays.” BMC Biomedical Engineering, vol. 4 (1), pp. 1-10.
Mesut Sahin, , Chunkyun Seok , Feysel Yalcin Yamaner , Mesut Sahin, Omer Oralkan . 2021. “A Wearable Ultrasonic Neurostimulator-Part I: A 1D CMUT Phased Array System for Chronic Implantation in Small Animals.” IEEE Transactions on Biomedical Circuits and Systems.
Ahmet S Asan , Qi Kang , Ömer Oralkan , Mesut Sahin. 2021. “Entrainment of cerebellar Purkinje cell spiking activity using pulsed ultrasound stimulation.” Brain Stimulation.
Ahmet Asan, Eric Lang, Mesut Sahin. 2020. “Entrainment of cerebellar purkinje cells with directional AC electric fields in anesthetized rats.” Brain Stimulation.
ferhat Erdogan, Mesut Sahin. 2019. “Genioglossal Response to Mechanical Vibrations of the Mandible and the Sub-Mandibular Muscles.” Journal of Applied Physiology.
ahmet asan, sinan gok, Mesut Sahin. 2019. “Electrical Fields Induced Inside the Rat Brain with Skin, Skull, and Dural Placements of the Current Injection Electrode.” .
Sinan Gok, Mesut Sahin. 2019. “Prediction of Forelimb EMGs and Movement Phases from Corticospinal Signals in the Rat During the Reach-to-Pull Task.” Int. J. of Neural Systems.
Yi Guo, Sinan Gok, Mesut Sahin. 2018. “Convolutional networks outperform linear decoders in predicting EMG from spinal cord signals.” Frontiers in Neuroscience.
esma cetinkaya, sinan gok, Mesut Sahin. 2018. “Carbon Fiber Electrodes For In Vivo Spinal Cord Recordings.” Int. Conf. IEEE EMBC.
Sinan Gok, Mesut Sahin. 2017. “Rat Forelimb Movement Components Segregated By Corticospinal Tract Activity.” IEEE /EMBS Conference on Neural Engineering.
Lu Wang, David Freedman, Mesut Sahin, Selim Unlu, Ronald Knepper. 2016. “Active C4 Electrodes for Local Field Potential Recording Applications.” Sensors.
Ali Ersen, Mesut Sahin, Stella Elkabes. 2015. “Chronic Tissue Response to Unthetered Electrodes.” Journal of Neural Engineering.
Jonathan Groth, Mesut Sahin. 2015. “High Frequency Synchrony in the Cerebellar Cortex during Goal Directed Movements.” Frontiers in Neuroscience.
Huseyin Guruler, Mesut Sahin, Abdullah Ferikoglu. 2014. “Feature Selection on Single-lead ECG for OSA.” Turkish Journal of Electrical Engineering & Computer Sciences, vol. 22, pp. 465-478.
Gokhan Ordek, Archana Proddutur, Vijavalaskhmi Santhakumar, Bryan J. Pfister, Mesut Sahin. 2014. “Monitoring of Cerebellar Evoked Potentials with micro ECoG Following Fluid Percussion Injury.” Journal of Frontiers in Neuroscience.
yi guo, Mesut Sahin, Richard A. Foulds, Sergei Adamovich. 2014. “Encoding of forelimb forces by corticospinal tract activity in the rat.” Frontiers in Neuroprosthetics, vol. 8, no. 62, pp. 7 pages.
Elif C Seymour, David S. Freedman, M. Gokkavas, Ekrem Ozbay, Mesut Sahin, Selim Unlu. 2014. “Improved Selectivity From a Wavelength Addressable Device for Wireless Stimulation of Neural Tissue.” Frontiers in Neuroengineering, vol. 7, no. 5, pp. 12 pages.
Ali Ersen, Ammar Abdo, Mesut Sahin. 2014. “Temperature elevation profile inside the rat brain induced by a laser beam .” J. Biomedical Optics, vol. 19, no. 1, pp. 7 pages.
Ammar Abdo, Ali Ersen, Mesut Sahin. 2013. “Near light penetration profile in the rodent brain.” Journal of Biomedical Optics, vol. 18, no. 7, pp. 6 pages.
Gokhan ordek, Jonathan D Groth, Mesut Sahin. 2012. “Effect of anesthesia on spontaneous and evoked activity of the cerebellar cortex.” J. of Neurophysiology, vol. 109, pp. 9 pages.
Abhishek Prasad, Mesut Sahin. 2012. “Can volition be extracted from the spinal cord ?.” Journal of NeuroEngineering and Rehabilitation, vol. vol 9, no. 41, pp. 13 pages.
Ammar Abdo, Mesut Sahin. 2011. “Floating light-activated micro electrical stimulators tested in the rat spinal cord.” J. Neural Eng., vol. vol. 8.
Abhishek Prasad, Mesut Sahin. 2010. “Characterization of Neural Activity Recorded from the Descending Tracts of the Rat Spinal Cord..” Frontiers in Neuroscience, vol. vol. 4, no. article 21, pp. pp. 1-7.
Mesut Sahin, , Chunkyun Seok , Feysel Yalcin Yamaner , Mesut Sahin, Omer Oralkan . 2021. “A Wearable Ultrasonic Neurostimulator-Part I: A 1D CMUT Phased Array System for Chronic Implantation in Small Animals.” IEEE Transactions on Biomedical Circuits and Systems.
Ahmet S Asan , Qi Kang , Ömer Oralkan , Mesut Sahin. 2021. “Entrainment of cerebellar Purkinje cell spiking activity using pulsed ultrasound stimulation.” Brain Stimulation.
Ahmet Asan, Eric Lang, Mesut Sahin. 2020. “Entrainment of cerebellar purkinje cells with directional AC electric fields in anesthetized rats.” Brain Stimulation.
ferhat Erdogan, Mesut Sahin. 2019. “Genioglossal Response to Mechanical Vibrations of the Mandible and the Sub-Mandibular Muscles.” Journal of Applied Physiology.
ahmet asan, sinan gok, Mesut Sahin. 2019. “Electrical Fields Induced Inside the Rat Brain with Skin, Skull, and Dural Placements of the Current Injection Electrode.” .
Sinan Gok, Mesut Sahin. 2019. “Prediction of Forelimb EMGs and Movement Phases from Corticospinal Signals in the Rat During the Reach-to-Pull Task.” Int. J. of Neural Systems.
Yi Guo, Sinan Gok, Mesut Sahin. 2018. “Convolutional networks outperform linear decoders in predicting EMG from spinal cord signals.” Frontiers in Neuroscience.
esma cetinkaya, sinan gok, Mesut Sahin. 2018. “Carbon Fiber Electrodes For In Vivo Spinal Cord Recordings.” Int. Conf. IEEE EMBC.
Sinan Gok, Mesut Sahin. 2017. “Rat Forelimb Movement Components Segregated By Corticospinal Tract Activity.” IEEE /EMBS Conference on Neural Engineering.
Lu Wang, David Freedman, Mesut Sahin, Selim Unlu, Ronald Knepper. 2016. “Active C4 Electrodes for Local Field Potential Recording Applications.” Sensors.
Ali Ersen, Mesut Sahin, Stella Elkabes. 2015. “Chronic Tissue Response to Unthetered Electrodes.” Journal of Neural Engineering.
Jonathan Groth, Mesut Sahin. 2015. “High Frequency Synchrony in the Cerebellar Cortex during Goal Directed Movements.” Frontiers in Neuroscience.
Huseyin Guruler, Mesut Sahin, Abdullah Ferikoglu. 2014. “Feature Selection on Single-lead ECG for OSA.” Turkish Journal of Electrical Engineering & Computer Sciences, vol. 22, pp. 465-478.
Gokhan Ordek, Archana Proddutur, Vijavalaskhmi Santhakumar, Bryan J. Pfister, Mesut Sahin. 2014. “Monitoring of Cerebellar Evoked Potentials with micro ECoG Following Fluid Percussion Injury.” Journal of Frontiers in Neuroscience.
yi guo, Mesut Sahin, Richard A. Foulds, Sergei Adamovich. 2014. “Encoding of forelimb forces by corticospinal tract activity in the rat.” Frontiers in Neuroprosthetics, vol. 8, no. 62, pp. 7 pages.
Elif C Seymour, David S. Freedman, M. Gokkavas, Ekrem Ozbay, Mesut Sahin, Selim Unlu. 2014. “Improved Selectivity From a Wavelength Addressable Device for Wireless Stimulation of Neural Tissue.” Frontiers in Neuroengineering, vol. 7, no. 5, pp. 12 pages.
Ali Ersen, Ammar Abdo, Mesut Sahin. 2014. “Temperature elevation profile inside the rat brain induced by a laser beam .” J. Biomedical Optics, vol. 19, no. 1, pp. 7 pages.
Ammar Abdo, Ali Ersen, Mesut Sahin. 2013. “Near light penetration profile in the rodent brain.” Journal of Biomedical Optics, vol. 18, no. 7, pp. 6 pages.
Gokhan ordek, Jonathan D Groth, Mesut Sahin. 2012. “Effect of anesthesia on spontaneous and evoked activity of the cerebellar cortex.” J. of Neurophysiology, vol. 109, pp. 9 pages.
Abhishek Prasad, Mesut Sahin. 2012. “Can volition be extracted from the spinal cord ?.” Journal of NeuroEngineering and Rehabilitation, vol. vol 9, no. 41, pp. 13 pages.
Ammar Abdo, Mesut Sahin. 2011. “Floating light-activated micro electrical stimulators tested in the rat spinal cord.” J. Neural Eng., vol. vol. 8.
Abhishek Prasad, Mesut Sahin. 2010. “Characterization of Neural Activity Recorded from the Descending Tracts of the Rat Spinal Cord..” Frontiers in Neuroscience, vol. vol. 4, no. article 21, pp. pp. 1-7.
COLLAPSE
Conference Paper
“Entrainment of Cerebellar Nuclear Cells via AC Stimulation of the Cerebellar Cortex”
April (2nd Quarter/Spring) 2023.
April (2nd Quarter/Spring) 2023.
Book
Mesut Sahin, Howard Fidel, Raquel Perez-Castillejos. 2020. “ Book Instrumentation Handbook for Biomedical Engineers.” 216 pp. Boca Raton, : Taylor and Francis Group, 2020. ISBN 9780429193989.
Conference Proceeding
“A Sub-Millimeter Spatial Resolution Ultrasonic Beamforming System for Brain Stimulation in Behaving Animals”
Int. Conf. of IEEE EMBC, July (3rd Quarter/Summer) 2019.
“Modulation of Multiunit Spike Activity by Transcranial AC Stimulation (tACS) in the Rat Cerebellar Cortex”
Int. Conf. on IEEE EMBC, July (3rd Quarter/Summer) 2019.
“Electric Fields Induced by Transcutaneous and Intracranial Current Injections in the Rat Brain”
Int. Conf. of IEEE EMBC, July (3rd Quarter/Summer) 2018.
“Assessment of Cerebellar Injury in Rats Using Evoked Potentials and a Behavioral Task”
Annual Meeting of Biomedical Engineering Society,
“Carbon Fiber Electrodes for Recording Spinal Cord Activity in Rats”
Annual Meeting of Biomedical Engineering Society,
Int. Conf. of IEEE EMBC, July (3rd Quarter/Summer) 2019.
“Modulation of Multiunit Spike Activity by Transcranial AC Stimulation (tACS) in the Rat Cerebellar Cortex”
Int. Conf. on IEEE EMBC, July (3rd Quarter/Summer) 2019.
“Electric Fields Induced by Transcutaneous and Intracranial Current Injections in the Rat Brain”
Int. Conf. of IEEE EMBC, July (3rd Quarter/Summer) 2018.
“Assessment of Cerebellar Injury in Rats Using Evoked Potentials and a Behavioral Task”
Annual Meeting of Biomedical Engineering Society,
“Carbon Fiber Electrodes for Recording Spinal Cord Activity in Rats”
Annual Meeting of Biomedical Engineering Society,
SHOW MORE
“Human Jaw-Tongue Reflex Evoked by High Frequency Mandibular Vibrations”
Annual Meeting of Biomedical Engineering Society,
“Electrophysiological patterns of the cerebellum injury with subdural recordings”
Society for Neuroscience, November 2016.
“PDMS-Based Optical Waveguides for Transcutaneous Powering of Microelectrode Arrays”
IEEE EMBC Annual International Conference, Orlando, FL, August 2016.
“Prediction of forelimb EMG signals using corticospinal cord signals”
IEEE EMBC Annual International Conference, Orlando, FL, August 2016.
“In Vivo Impedance Characterization of PEDOT:TFB Coated and Chronically Implanted Multi Electrode Arrays”
October (4th Quarter/Autumn) 2015.
“A Method of Chronic Neural Recording From Rat Corticospinal Tract Using Flexible Multi-Electrode Arrays”
Annual Meeting of Biomedical Engineering Society,
“A Method of Chronic Neural Recording From Rat Corticospinal Tract Using Flexible Multi-Electrode Arrays”
Neural Interface Conference, Dallas, TX, May 2015.
“Chronic Tissue Response to Floating Light Activated Micro-Electrical Stimulators in Rat Spinal Cord and Brain”
Neural Interface Conference, Dallas, TX, May 2015.
“Cross Frequency Interactions of Oscillations in the Cerebellum”
Society for Neuroscience,
“Impact of Brain Injury on High Frequency Cerebellar Oscillations in Rat”
Society for Neuroscience,
“PDMS-based Optical Conduit for Powering Untethered Neural Microstimulators”
Annual Minnesota Neuroprosthetic Symposium, April (2nd Quarter/Spring) 2015.
“Spatial Patterns of Synchronous High-Frequency Activity in the Rat Cerebellar Cortex”
IEEE EMBS COnference, April (2nd Quarter/Spring) 2014.
“The ladder rung walking task as a technique to quantify traumatic cerebellar injury in rats”
Annual Meeting of Biomedical Engineering Society, April (2nd Quarter/Spring) 2014.
“Electrophysiological monitoring of cerebellar evoked potentials following fluid percussion injury.”
6th International IEEE EMBS Conference on Neural Engineering, November 2013.
“FEA Modeling of Temperature Elevation in Neural Tissue Illuminated by a Laser: Transient Effects”
November 2013.
“Corticospinal signals recorded with MEAs can predict the volitional forearm forces in rats”
Conf Proc IEEE Eng Med Biol Soc., IEEE, October (4th Quarter/Autumn) 2013.
Annual Meeting of Biomedical Engineering Society,
“Electrophysiological patterns of the cerebellum injury with subdural recordings”
Society for Neuroscience, November 2016.
“PDMS-Based Optical Waveguides for Transcutaneous Powering of Microelectrode Arrays”
IEEE EMBC Annual International Conference, Orlando, FL, August 2016.
“Prediction of forelimb EMG signals using corticospinal cord signals”
IEEE EMBC Annual International Conference, Orlando, FL, August 2016.
“In Vivo Impedance Characterization of PEDOT:TFB Coated and Chronically Implanted Multi Electrode Arrays”
October (4th Quarter/Autumn) 2015.
“A Method of Chronic Neural Recording From Rat Corticospinal Tract Using Flexible Multi-Electrode Arrays”
Annual Meeting of Biomedical Engineering Society,
“A Method of Chronic Neural Recording From Rat Corticospinal Tract Using Flexible Multi-Electrode Arrays”
Neural Interface Conference, Dallas, TX, May 2015.
“Chronic Tissue Response to Floating Light Activated Micro-Electrical Stimulators in Rat Spinal Cord and Brain”
Neural Interface Conference, Dallas, TX, May 2015.
“Cross Frequency Interactions of Oscillations in the Cerebellum”
Society for Neuroscience,
“Impact of Brain Injury on High Frequency Cerebellar Oscillations in Rat”
Society for Neuroscience,
“PDMS-based Optical Conduit for Powering Untethered Neural Microstimulators”
Annual Minnesota Neuroprosthetic Symposium, April (2nd Quarter/Spring) 2015.
“Spatial Patterns of Synchronous High-Frequency Activity in the Rat Cerebellar Cortex”
IEEE EMBS COnference, April (2nd Quarter/Spring) 2014.
“The ladder rung walking task as a technique to quantify traumatic cerebellar injury in rats”
Annual Meeting of Biomedical Engineering Society, April (2nd Quarter/Spring) 2014.
“Electrophysiological monitoring of cerebellar evoked potentials following fluid percussion injury.”
6th International IEEE EMBS Conference on Neural Engineering, November 2013.
“FEA Modeling of Temperature Elevation in Neural Tissue Illuminated by a Laser: Transient Effects”
November 2013.
“Corticospinal signals recorded with MEAs can predict the volitional forearm forces in rats”
Conf Proc IEEE Eng Med Biol Soc., IEEE, October (4th Quarter/Autumn) 2013.
COLLAPSE
Chapter
David S. Freeman, Mesut Sahin, Bruce Towe. 2013. “Wireless Stimulators.” , International: Springer, 2013.
Professional
IEEE Transactions on Neural Systems and Rehabilitation Engineering
Editor, Associate Editor, 2024
IEEE Tran. on Biomedical Circuits and Systems
Guest Editor, 2019
Editor, Associate Editor, 2024
IEEE Tran. on Biomedical Circuits and Systems
Guest Editor, 2019