Wenge Guo
Associate Professor, Mathematical Sciences
210B Cullimore Hall (CULM)
Education
Ph.D.
; University of Cincinnati
; Biostatistics
; 2007
M.S. ; North Dakora State University ; ; 2004
M.S. ; North Dakora State University ; ; 2004
Website
2026 Spring Courses
MATH 478 - STAT METHODS IN DATA SCI
MATH 790A - DOCT DISSERTATION & RES
MATH 792B - PRE DOCTORAL RESEARCH
MATH 461 - INTRO STATISTICAL COMP SAS/R
MATH 790A - DOCT DISSERTATION & RES
MATH 792B - PRE DOCTORAL RESEARCH
MATH 461 - INTRO STATISTICAL COMP SAS/R
Teaching Interests
Advanced Statistical Learning, Introduction to Statistical Methods
in Data Science, Statistical Inference, Regression analysis methods, Design and analysis of clinical trials, Introduction to Statistical Computing with SAS and R, Survival Analysis, Stochastic Simulations.
in Data Science, Statistical Inference, Regression analysis methods, Design and analysis of clinical trials, Introduction to Statistical Computing with SAS and R, Survival Analysis, Stochastic Simulations.
Past Courses
MATH 333: PROBABILITY AND STATISTICS
MATH 344: REGRESSION ANALYSIS
MATH 447: APPLIED TIME SERIES ANALYSIS
MATH 448: STOCHASTIC SIMULATION
MATH 461: INTRODUCTION TO STATISTICAL COMPUTING WITH SAS AND R
MATH 478: STAT METHODS IN DATA SCI
MATH 644: REGRESSION ANALYSIS METH
MATH 644: REGRESSION ANALYSIS METHODS
MATH 654: CLINICAL TRIALS DESIGN &ANALYS
MATH 659: SURVIVAL ANALYSIS
MATH 660: INTRO TO STAT COMP W/ SAS & R
MATH 661: APPLIED STATISTICS
MATH 664: METHODS FOR STAT CONSULT
MATH 665: STATISTICAL INFERENCE
MATH 678: STAT METHODS IN DATA SCIENCE
MATH 678: STATISTICAL METHODS IN DATA SCIENCE
MATH 680: ADVANCED STATISTICAL LEARNING
MATH 707: ST: INTRO TO STATISTICAL COMPUTING
MATH 344: REGRESSION ANALYSIS
MATH 447: APPLIED TIME SERIES ANALYSIS
MATH 448: STOCHASTIC SIMULATION
MATH 461: INTRODUCTION TO STATISTICAL COMPUTING WITH SAS AND R
MATH 478: STAT METHODS IN DATA SCI
MATH 644: REGRESSION ANALYSIS METH
MATH 644: REGRESSION ANALYSIS METHODS
MATH 654: CLINICAL TRIALS DESIGN &ANALYS
MATH 659: SURVIVAL ANALYSIS
MATH 660: INTRO TO STAT COMP W/ SAS & R
MATH 661: APPLIED STATISTICS
MATH 664: METHODS FOR STAT CONSULT
MATH 665: STATISTICAL INFERENCE
MATH 678: STAT METHODS IN DATA SCIENCE
MATH 678: STATISTICAL METHODS IN DATA SCIENCE
MATH 680: ADVANCED STATISTICAL LEARNING
MATH 707: ST: INTRO TO STATISTICAL COMPUTING
Research Interests
Large-scale multiple testing, Selective Inference, Statistical machine learning, High-dimensional data analysis, Bioinformatics, Statistical methods for clinical trials.
Conference Proceeding
"Two-stage Risk Control with Application to Ranked Retrieval"
International Joint Conferences on Artificial Intelligence Organization, September, 2025.
"Distribution-free Conformal Prediction for Ordinal Classification"
Proceedings of the Thirteenth Symposium on Conformal and Probabilistic Prediction with Applications, PMLR , September, 2024.
"Multi-label Classification under Uncertainty: A Tree-based Conformal Prediction Approach"
COPA 2023 : 12th Symposium on Conformal and Probabilistic Prediction with Applications, September, 2023.
"Conformal Risk Control for Ordinal Classification"
July (3rd Quarter/Summer), 2023.
International Joint Conferences on Artificial Intelligence Organization, September, 2025.
"Distribution-free Conformal Prediction for Ordinal Classification"
Proceedings of the Thirteenth Symposium on Conformal and Probabilistic Prediction with Applications, PMLR , September, 2024.
"Multi-label Classification under Uncertainty: A Tree-based Conformal Prediction Approach"
COPA 2023 : 12th Symposium on Conformal and Probabilistic Prediction with Applications, September, 2023.
"Conformal Risk Control for Ordinal Classification"
July (3rd Quarter/Summer), 2023.
Journal Article
Xiaolong Luo, Lerong Li, Oleksandr Savenkov, Weijian Liu, Xiao Ni, Weihua Tang, Wenge Guo.
2025. "Multiple Comparisons Procedures for Analyses of Joint Primary Endpoints and Secondary Endpoints."
Pharmaceutical Statistics , vol. 24 , no. 3 .
Santu Ghosh, Wenge Guo, Samiran Ghosh. 2022. "A hierarchical testing procedure for three arm non-inferiority trials." Computational Statistics & Data Analysis , vol. 174 , pp. 107521.
Wenge Guo, Sanat Sarkar. 2020. "Adaptive controls of FWER and FDR under block dependence." Journal of Statistical Planning and Inference , vol. 208 , pp. 13-24.
Boxiang Dong, Hui Wang, Anna Monreale, Dino Pedreschi, Fosca Giannotti, Wenge Guo. 2020. "Authenticated Outlier Mining for Outsourced Databases." IEEE Transactions on Dependable and Secure Computing , vol. 17 , no. 2 , pp. 222 - 235.
Yalin Zhu, Wenge Guo. 2020. "Familywise Error Rate Controlling Procedures for Discrete Data." Statistics in Biopharmaceutical Research , vol. 12 , pp. 117-128.
Santu Ghosh, Wenge Guo, Samiran Ghosh. 2022. "A hierarchical testing procedure for three arm non-inferiority trials." Computational Statistics & Data Analysis , vol. 174 , pp. 107521.
Wenge Guo, Sanat Sarkar. 2020. "Adaptive controls of FWER and FDR under block dependence." Journal of Statistical Planning and Inference , vol. 208 , pp. 13-24.
Boxiang Dong, Hui Wang, Anna Monreale, Dino Pedreschi, Fosca Giannotti, Wenge Guo. 2020. "Authenticated Outlier Mining for Outsourced Databases." IEEE Transactions on Dependable and Secure Computing , vol. 17 , no. 2 , pp. 222 - 235.
Yalin Zhu, Wenge Guo. 2020. "Familywise Error Rate Controlling Procedures for Discrete Data." Statistics in Biopharmaceutical Research , vol. 12 , pp. 117-128.
SHOW MORE
Anjana Grandhi, Wenge Guo, Joseph Romano.
2019. "Control of directional errors in fixed sequence multiple testing."
Statistica Sinica , vol. 29 , pp. 1047-1064.
Sanat K. Sarkar, Aiying Chen, Li He, Wenge Guo. 2019. "Group sequential BH and its adaptive versions controlling the FDR." Journal of Statistical Planning and Inference , vol. 199 , pp. 219-235.
Gavin Lynch, Wenge Guo, Sanat Sarkar, Helmut Finner. 2017. "The control of the false discovery rate in fixed sequence multiple testing. ." Electronic Journal of Statistics , vol. 11 , no. 2 , pp. 4649-4673.
Gavin Lynch, Wenge Guo, Sanat K. Sarkar, Helmut Finner. 2017. "The control of the false discovery rate in fixed sequence multiple testing." Electronic Journal of Statistics , vol. 11 , no. 2 .
Sanat K. Sarkar, Yiyong Fu, Wenge Guo. 2016. "Improving Holm's procedure using pairwise dependencies." Biometrika , vol. 103 , no. 1 , pp. 237-243.
Anjana Grandhi, Wenge Guo, Shyamal D. Peddada. 2016. "A multiple testing procedure for multi-dimensional pairwise comparisons with application to gene expression studies." BMC Bioinformatics , vol. 17 , no. 1 .
Zhiying Qiu, Wenge Guo, Gavin Lynch. 2015. "On generalized fixed sequence procedures for controlling the FWER." Statistics in Medicine , vol. 34 , no. 30 , pp. 3968-3983.
Wenge Guo, Joseph Romano. 2015. "On stepwise control of directional errors under independence and some dependence." Journal of Statistical Planning and Inference , vol. 163 , pp. 21-33.
Wenge Guo, Li He, Sanat Sarkar. 2014. "Further results on controlling false discovery proportion." Annals of Statistics , vol. 42 , no. 3 , pp. 1070--1101.
Wenge Guo, Li He, Sanat K. Sarkar. 2014. "Further results on controlling the false discovery proportion." The Annals of Statistics , vol. 42 , no. 3 .
Sanat K. Sarkar, Jingjing Chen, Wenge Guo. 2013. "Multiple Testing in a Two-Stage Adaptive Design With Combination Tests Controlling FDR." Journal of the American Statistical Association , vol. 108 , no. 504 , pp. 1385-1401.
Sanat K. Sarkar, Jing Chen, Wenge Guo. 2013. "Controlling the false discovery rate in two-stage combination tests for multiple endpoints." Journal of the American Statistical Association , vol. 108 , no. 504 , pp. 1385--1401.
Wenge Guo, Mingan Yang, Chuanhua Xing, Shyamal D Peddada. 2012. "Analysis of high dimensional data using pre-defined set and subset information, with applications to genomic data." BMC Bioinformatics , vol. 13 , no. 1 .
Wenge Guo, Mingan Yang, Chuanhua Xing, Shyamal Peddada. 2012. "Analysis of high dimensional data using pre-defined set and subset information, with applications to genomic data." BMC Bioinformatics , vol. 13 , pp. 177.
Sanat K. Sarkar, Wenge Guo, Helmut Finner. 2012. "On adaptive procedures controlling the familywise error rate.." Journal of Statistical Planning and Inference , vol. 142 , pp. 65-78.
Wenge Guo, M. Bhaskara Rao. 2010. "On stepwise control of the generalized familywise error rates." Electronic Journal of Statistics , vol. 4 , pp. 472–485.
Sanat K. Sarkar, Wenge Guo. 2010. "Procedures controlling generalized false discovery rate using bivariate distributions of the null p-values." Statistica Sinica , vol. 20 , no. 3 , pp. 1227-1238.
Wenge Guo, Sanat K. Sarkar, Shyamal D. Peddada. 2010. "Controlling False Discoveries in Multidimensional Directional Decisions, with Applications to Gene Expression Data on Ordered Categories." Biometrics , vol. 66 , no. 2 , pp. 485-492.
Wenge Guo, M. Bhaskara Rao. 2010. "On stepwise control of the generalized familywise error rate." Electronic Journal of Statistics , vol. 4 , no. none .
Wenge Guo. 2009. " A note on adaptive Bonferroni and Holm's procedures under dependence." Biometrika , vol. 96 , no. 4 , pp. 1012-1018.
Sanat K. Sarkar, Wenge Guo. 2009. "On a generalized false discovery rate." The Annals of Statistics , vol. 37 , no. 3 .
Wenge Guo, M. Bhaskara Rao. 2008. "On control of the false discovery rate under no assumption of dependency." Journal of Statistical Planning and Inference , vol. 138 , no. 10 , pp. 3176-3188.
Wenge Guo, M. Bhaskara Rao. 2008. "On optimality of the Benjamini–Hochberg procedure for the false discovery rate." Statistics & Probability Letters , vol. 78 , no. 14 , pp. 2024-2030.
Wenge Guo, Shyamal Peddada. 2008. "Adaptive Choice of the Number of Bootstrap Samples in Large Scale Multiple Testing." Statistical Applications in Genetics and Molecular Biology , vol. 7 , no. 1 .
Wenge Guo, Joseph Romano. 2007. "A Generalized Sidak-Holm Procedure and Control of Generalized Error Rates under Independence." Statistical Applications in Genetics and Molecular Biology , vol. 6 , no. 1 .
Sanat K. Sarkar, Aiying Chen, Li He, Wenge Guo. 2019. "Group sequential BH and its adaptive versions controlling the FDR." Journal of Statistical Planning and Inference , vol. 199 , pp. 219-235.
Gavin Lynch, Wenge Guo, Sanat Sarkar, Helmut Finner. 2017. "The control of the false discovery rate in fixed sequence multiple testing. ." Electronic Journal of Statistics , vol. 11 , no. 2 , pp. 4649-4673.
Gavin Lynch, Wenge Guo, Sanat K. Sarkar, Helmut Finner. 2017. "The control of the false discovery rate in fixed sequence multiple testing." Electronic Journal of Statistics , vol. 11 , no. 2 .
Sanat K. Sarkar, Yiyong Fu, Wenge Guo. 2016. "Improving Holm's procedure using pairwise dependencies." Biometrika , vol. 103 , no. 1 , pp. 237-243.
Anjana Grandhi, Wenge Guo, Shyamal D. Peddada. 2016. "A multiple testing procedure for multi-dimensional pairwise comparisons with application to gene expression studies." BMC Bioinformatics , vol. 17 , no. 1 .
Zhiying Qiu, Wenge Guo, Gavin Lynch. 2015. "On generalized fixed sequence procedures for controlling the FWER." Statistics in Medicine , vol. 34 , no. 30 , pp. 3968-3983.
Wenge Guo, Joseph Romano. 2015. "On stepwise control of directional errors under independence and some dependence." Journal of Statistical Planning and Inference , vol. 163 , pp. 21-33.
Wenge Guo, Li He, Sanat Sarkar. 2014. "Further results on controlling false discovery proportion." Annals of Statistics , vol. 42 , no. 3 , pp. 1070--1101.
Wenge Guo, Li He, Sanat K. Sarkar. 2014. "Further results on controlling the false discovery proportion." The Annals of Statistics , vol. 42 , no. 3 .
Sanat K. Sarkar, Jingjing Chen, Wenge Guo. 2013. "Multiple Testing in a Two-Stage Adaptive Design With Combination Tests Controlling FDR." Journal of the American Statistical Association , vol. 108 , no. 504 , pp. 1385-1401.
Sanat K. Sarkar, Jing Chen, Wenge Guo. 2013. "Controlling the false discovery rate in two-stage combination tests for multiple endpoints." Journal of the American Statistical Association , vol. 108 , no. 504 , pp. 1385--1401.
Wenge Guo, Mingan Yang, Chuanhua Xing, Shyamal D Peddada. 2012. "Analysis of high dimensional data using pre-defined set and subset information, with applications to genomic data." BMC Bioinformatics , vol. 13 , no. 1 .
Wenge Guo, Mingan Yang, Chuanhua Xing, Shyamal Peddada. 2012. "Analysis of high dimensional data using pre-defined set and subset information, with applications to genomic data." BMC Bioinformatics , vol. 13 , pp. 177.
Sanat K. Sarkar, Wenge Guo, Helmut Finner. 2012. "On adaptive procedures controlling the familywise error rate.." Journal of Statistical Planning and Inference , vol. 142 , pp. 65-78.
Wenge Guo, M. Bhaskara Rao. 2010. "On stepwise control of the generalized familywise error rates." Electronic Journal of Statistics , vol. 4 , pp. 472–485.
Sanat K. Sarkar, Wenge Guo. 2010. "Procedures controlling generalized false discovery rate using bivariate distributions of the null p-values." Statistica Sinica , vol. 20 , no. 3 , pp. 1227-1238.
Wenge Guo, Sanat K. Sarkar, Shyamal D. Peddada. 2010. "Controlling False Discoveries in Multidimensional Directional Decisions, with Applications to Gene Expression Data on Ordered Categories." Biometrics , vol. 66 , no. 2 , pp. 485-492.
Wenge Guo, M. Bhaskara Rao. 2010. "On stepwise control of the generalized familywise error rate." Electronic Journal of Statistics , vol. 4 , no. none .
Wenge Guo. 2009. " A note on adaptive Bonferroni and Holm's procedures under dependence." Biometrika , vol. 96 , no. 4 , pp. 1012-1018.
Sanat K. Sarkar, Wenge Guo. 2009. "On a generalized false discovery rate." The Annals of Statistics , vol. 37 , no. 3 .
Wenge Guo, M. Bhaskara Rao. 2008. "On control of the false discovery rate under no assumption of dependency." Journal of Statistical Planning and Inference , vol. 138 , no. 10 , pp. 3176-3188.
Wenge Guo, M. Bhaskara Rao. 2008. "On optimality of the Benjamini–Hochberg procedure for the false discovery rate." Statistics & Probability Letters , vol. 78 , no. 14 , pp. 2024-2030.
Wenge Guo, Shyamal Peddada. 2008. "Adaptive Choice of the Number of Bootstrap Samples in Large Scale Multiple Testing." Statistical Applications in Genetics and Molecular Biology , vol. 7 , no. 1 .
Wenge Guo, Joseph Romano. 2007. "A Generalized Sidak-Holm Procedure and Control of Generalized Error Rates under Independence." Statistical Applications in Genetics and Molecular Biology , vol. 6 , no. 1 .
COLLAPSE
Other
"Distribution-Free Conformal Prediction for Ordinal Classification"
Elsevier BV, 2024.
Elsevier BV, 2024.
Software
"R package MHTmult: Multiple Hypotheses Testing for Multiple Families/Groups Structure"
May, 2017.
"R package MHTdiscrete: Multiple Hypotheses Testing for Discrete Data"
February, 2017.
"R package FixSeqMTP: Fixed Sequence Multiple Testing Procedures"
January (1st Quarter/Winter), 2017.
May, 2017.
"R package MHTdiscrete: Multiple Hypotheses Testing for Discrete Data"
February, 2017.
"R package FixSeqMTP: Fixed Sequence Multiple Testing Procedures"
January (1st Quarter/Winter), 2017.
Chapter
Wenge Guo, Sanat Sarkar.
"Stepdown procedures controlling a generalized false discovery rate."
In A. SenGupta, T. Samanta, and A. Basu, eds.,
pp. 53-70. World Scientific, 2014.
Ruilin Liu, Hui Wang, Anna Monreale, Dino Pedreschi, Fosca Giannotti, Wenge Guo. "AUDIO: An Integrity $\underline{Audi}$ ting Framework of $\underline{O}$ utlier-Mining-as-a-Service Systems." "Lecture Notes in Computer Science," pp. 1-18. Springer Berlin Heidelberg, 2012.
Nicolle Clements, Sanat Sarkar, Wenge Guo. " Astronomical transient detection controlling the false discovery rate." In Eric D. Feigelson and G. Jogesh Babu, eds., pp. 383-396. Springer, 2012.
Wenge Guo, Sanat K. Sarkar, Shyamal P. Peddada. "Adaptive multiple testing procedures under positive dependence." In M. Bhattacharjee, S. Sunil, S. Subramanian, eds., pp. 27-41. World Scientific Publishing Co. Pte. Ltd, 2011.
Wenge Guo, Subramanyam Kasala, M. Bhaskara Rao, Brian Tucker. "The Hat Problem and Some Variations." "Statistics for Industry and Technology," pp. 459-479. Birkhäuser Boston, 2006.
Ruilin Liu, Hui Wang, Anna Monreale, Dino Pedreschi, Fosca Giannotti, Wenge Guo. "AUDIO: An Integrity $\underline{Audi}$ ting Framework of $\underline{O}$ utlier-Mining-as-a-Service Systems." "Lecture Notes in Computer Science," pp. 1-18. Springer Berlin Heidelberg, 2012.
Nicolle Clements, Sanat Sarkar, Wenge Guo. " Astronomical transient detection controlling the false discovery rate." In Eric D. Feigelson and G. Jogesh Babu, eds., pp. 383-396. Springer, 2012.
Wenge Guo, Sanat K. Sarkar, Shyamal P. Peddada. "Adaptive multiple testing procedures under positive dependence." In M. Bhattacharjee, S. Sunil, S. Subramanian, eds., pp. 27-41. World Scientific Publishing Co. Pte. Ltd, 2011.
Wenge Guo, Subramanyam Kasala, M. Bhaskara Rao, Brian Tucker. "The Hat Problem and Some Variations." "Statistics for Industry and Technology," pp. 459-479. Birkhäuser Boston, 2006.