Hao Chen
Hao Chen
Professor, Chemistry and Environmental Science
232 York Center (YORK)
Education
Ph.D.; Purdue University; ; 2005
Website
2024 Fall Courses
CHEM 701B - MASTERS THESIS
CHEM 726 - INDEPENDENT STUDY II
CHEM 391 - RESEARCH AND INDEPENDENT STUDY
CHEM 492 - RESEARCH & INDEP STUDY
EVSC 592 - GRADUATE WORK EXPERIENCE II
EVSC 700B - MASTER'S PROJECT
EVSC 701C - MASTER'S THESIS
EVSC 790A - DOCTORAL DISSERTATION
EVSC 701B - MASTER'S THESIS
EVSC 726 - INDEPENDENT STUDY II
EVSC 792B - PRE-DOCTORAL RESEARCH
EVSC 591 - GRADUATE WORK EXPERIENCE I
EVSC 725 - INDEPENDENT STUDY I
CHEM 591 - GRADUATE CO-OP WORK EXPER II
CHEM 700B - MASTERS PROJECT
CHEM 701C - MASTERS THESIS
CHEM 725 - INDEPENDENT STUDY I
CHEM 792B - PRE-DOCTORAL RESEARCH
FRSC 491 - RESEARCH & INDEP STUDY I
CHEM 491 - RESEARCH & INDEP STUDY I
CHEM 590 - GRADUATE CO-OP WORK EXPER I
CHEM 790A - DOCTORAL DISSERTATION
FRSC 475 - FORENSIC CHEMISTRY & LAB
CHEM 726 - INDEPENDENT STUDY II
CHEM 391 - RESEARCH AND INDEPENDENT STUDY
CHEM 492 - RESEARCH & INDEP STUDY
EVSC 592 - GRADUATE WORK EXPERIENCE II
EVSC 700B - MASTER'S PROJECT
EVSC 701C - MASTER'S THESIS
EVSC 790A - DOCTORAL DISSERTATION
EVSC 701B - MASTER'S THESIS
EVSC 726 - INDEPENDENT STUDY II
EVSC 792B - PRE-DOCTORAL RESEARCH
EVSC 591 - GRADUATE WORK EXPERIENCE I
EVSC 725 - INDEPENDENT STUDY I
CHEM 591 - GRADUATE CO-OP WORK EXPER II
CHEM 700B - MASTERS PROJECT
CHEM 701C - MASTERS THESIS
CHEM 725 - INDEPENDENT STUDY I
CHEM 792B - PRE-DOCTORAL RESEARCH
FRSC 491 - RESEARCH & INDEP STUDY I
CHEM 491 - RESEARCH & INDEP STUDY I
CHEM 590 - GRADUATE CO-OP WORK EXPER I
CHEM 790A - DOCTORAL DISSERTATION
FRSC 475 - FORENSIC CHEMISTRY & LAB
Teaching Interests
Analytical chemistry, Forensic chemistry
Past Courses
CHEM 221: ANALYTICAL CHEM METHODS
CHEM 221: ANALYTICAL CHEMICAL METHODS
CHEM 222: ANALYTICAL CHEMISTRY
CHEM 714: PHARMACEUTICAL ANALYSIS
EVSC 791: ENVIRONMENTAL SCIENCE SEMINAR
FRSC 475: FORENSIC CHEMISTRY
FRSC 475: FORENSIC CHEMISTRY & LAB
CHEM 221: ANALYTICAL CHEMICAL METHODS
CHEM 222: ANALYTICAL CHEMISTRY
CHEM 714: PHARMACEUTICAL ANALYSIS
EVSC 791: ENVIRONMENTAL SCIENCE SEMINAR
FRSC 475: FORENSIC CHEMISTRY
FRSC 475: FORENSIC CHEMISTRY & LAB
Research Interests
Analytical chemistry, mass spectrometry, electrochemistry, forensic chemistry, environmental chemistry
Journal Article
FNU, Praneeth Ivan Joel , & Hassan, Md. Tanim-Al, & Yaroshuk, Timothy , & Ai, Yongling , & Chen, Hao (2024). Absolute Quantitation of Peptides and Proteins by Coulometric Mass Spectrometry After Derivatization. Int. J. Mass Spectrom., 495, 117153.
Chen, Hao, & Ai, Yongling (2024). Development of Coulometric Mass Spectrometry for Absolute Chemical Quantitation. Encyclopedia of Analytical Chemistry, DOI: 10.1002/9780470027318.a9811.,
Wu, Chen, & Goodrow, Sandra , & Chen, Hao, & Li, Mengyan (2024). Distinctive Biotransformation and Biodefluorination of 6:2 versus 5:3 Fluorotelomer Carboxylic Acids by Municipal Activated Sludge. Water Research, 254, 121431.
Wei, Jingwen , & Pham, Thong , & Attah, Emamanuel , & Liu, Mengjia , & Yaroshuk, Timothy , & Chen, Hao, & Wojtas, Lukasz , & Shi, Xiaodong (2024). Gold-Catalyzed Diyne-Ene Condensation for the Synthesis of Dense-Function Benzenes (DFBs) through Formal [3+3] Approach with Amide as the Critical Co-Catalyst. Angew. Chem. Int. Ed., in press,
Osonga, Francis J. , & Eshun, Gaddi B. , & Xue, Huize , & Kurilla, Stephen , & Hassan, Md. Tanim-Al , & Qamar, Areej , & Chen, Hao, & Sadik, Omowunmi A. (2024). IMPACT: Innovative (nano)Materials and Processes for Advanced Catalytic Technologies to Detect and Degrade PFOA in Water. Chemosphere, in press,
Chen, Hao, & Ai, Yongling (2024). Development of Coulometric Mass Spectrometry for Absolute Chemical Quantitation. Encyclopedia of Analytical Chemistry, DOI: 10.1002/9780470027318.a9811.,
Wu, Chen, & Goodrow, Sandra , & Chen, Hao, & Li, Mengyan (2024). Distinctive Biotransformation and Biodefluorination of 6:2 versus 5:3 Fluorotelomer Carboxylic Acids by Municipal Activated Sludge. Water Research, 254, 121431.
Wei, Jingwen , & Pham, Thong , & Attah, Emamanuel , & Liu, Mengjia , & Yaroshuk, Timothy , & Chen, Hao, & Wojtas, Lukasz , & Shi, Xiaodong (2024). Gold-Catalyzed Diyne-Ene Condensation for the Synthesis of Dense-Function Benzenes (DFBs) through Formal [3+3] Approach with Amide as the Critical Co-Catalyst. Angew. Chem. Int. Ed., in press,
Osonga, Francis J. , & Eshun, Gaddi B. , & Xue, Huize , & Kurilla, Stephen , & Hassan, Md. Tanim-Al , & Qamar, Areej , & Chen, Hao, & Sadik, Omowunmi A. (2024). IMPACT: Innovative (nano)Materials and Processes for Advanced Catalytic Technologies to Detect and Degrade PFOA in Water. Chemosphere, in press,
SHOW MORE
Chiu, Kai-Yuan, & Ai, Yongling , & Hassan, Md. Tanim-Al , & Li, Xuanwen , & Gunawardena, Harsha , & Chen, Hao (2024). Kai-Yuan Chiu, Yongling Ai, Md. Tanim-Al Hassan, Xuanwen Li, Harsha Gunawardena, Hao Chen*, Standards-Free Absolute Quantitation of Oxidizable Glycopeptides by Coulometric Mass Spectrometry. J. Am. Soc. Mass Spectrom., 35, 1441−1450.
Bhattarai, Matrika , & Wang, Qi , & Hassan, Md. Tanim-Al , & Hussain, Zawar , & Chen, Hao, & Faik, Ahmed (2024). New insights on beta-glycan synthases using in vitro GT-array (i-GT-ray) platform. Plant Physiology and Biochemistry, in press,
Hassan, Md. Tanim-Al, & Chen, Xingzhi , & FNU, Praneeth Ivan Joel , & Osonga, Francis J. , & Sadik, Omowunmi A. , & Li, Mengyan , & Chen, Hao (2024). Rapid Detection of Per- and Polyfluoroalkyl Substances (PFAS) Using Paper Spray-Based Mass Spectrometry. Journal of Hazardous Materials, 465, 133366 .
Bhattarai, Matrika , & Wang, Qi , & Javaid, Tasleem , & Venkataraghavan, Akshayaa , & Hassan, Md Tanim-Al , & O’Neil, Malcolm , & Tan, Li , & Chen, Hao, & Faik, Ahmed (2024). Streamlining enzyme assays of glycosyltransferases activity using in vitro GT-array (i-GT-ray) platform: Application to family GT37 fucosyltransferases. Journal of Biological Chemistry, 300, 105734.
Wu, Chen, & Goodrow, Sandra, & Chen, Hao, & Li, Mengyan (2024). Distinctive biotransformation and biodefluorination of 6:2 versus 5:3 fluorotelomer carboxylic acids by municipal activated sludge. Water Research, 254,
Hassan, Md Tanim, & Chen, Xingzhi, & Fnu, Praneeth Ivan, & Osonga, Francis J., & Sadik, Omowunmi, & Li, Mengyan, & Chen, Hao (2024). Rapid detection of per- and polyfluoroalkyl substances (PFAS) using paper spray-based mass spectrometry. Journal of Hazardous Materials, 465,
Chen, Hao, & Wang, Chun (2023). Converting waste expanded polystyrene into higher-value-added hyper-crosslinked porous polymer for rapid and high-efficient adsorption of aflatoxins. Journal of Cleaner Production, 408, 137102.
Wan, Zhaoxiong, & Yu, Shupei, & Wang, Qi, & Sambath, Karthik, & Harty, Roshena, & Liu, Xiangshan, & Chen, Hao, & Wang, Chen, & Liu, Xuan, & Zhang, Yuanwei (2023). Far-red BODIPY-based oxime esters: photo-uncaging and drug delivery. Journal of Materials Chemistry B, 11(41), 9889--9893.
Yu, Shupei , & Reddy, Ojasvita , & Abaci, Alperen , & Ai, Yongling , & Li, Yanmei , & Chen, Hao, & Guvendiran, Murat , & Belfield, Kevin , & Zhang, Yuanwei (2023). Novel BODIPY-based photobase generators for photo-induced polymerization. ACS Applied Materials & Interfaces, 15, 45281–45289.
Li, Yanmei , & Castañeda-Bagatella, Diana M. , & Kakkad, Dhyeyi , & Ai, Yongling , & Chen, Hao, & Champagne, Pier Alexandre (2023). Synthetic and mechanistic study on the conjugate isothiocyanation of enones with trimethylsilyl isothiocyanate . Organic & Biomolecular Chemistry, 21, 9583-9590.
Li, Yanmei, & Castaneda Bagatella, Diana Marlén, & Kakkad, Dhyeyi, & Ai, Yongling, & Chen, Hao, & Champagne, Pier Alexandre (2023). Synthetic and mechanistic study on the conjugate isothiocyanation of enones with trimethylsilyl isothiocyanate. Organic & Biomolecular Chemistry, 21, 9583-9590.
Gewering, Theresa , & Waghray, Deepali , & Parey, Kristian , & Jung, Hendrik , & Tran, Nghi N.B. , & Zapata, Joel , & Zhao, Pengyi , & Chen, Hao, & Januliene, Dovile , & Hummer, Gerhard , & Urbatsch, Ina L. , & Moeller, Arne , & Zhang, Qinghai (2023). Tracing the substrate translocation mechanism in P-glycoprotein. eLife, 12, RP90174 .
Shen, Yucong, & Shih, Frank Y., & Chen, Hao (2023). Drug toxicity prediction by machine learning approaches. Pattern Recognition and Artificial Intelligence, 37(8), 2351013 (14 pages).
López Ruiz, Aida, & Xiao, Mengyuan, & Sathya, Asmitha, & Piccininni, Nicole, & Liu, Guangliang, & Siddiq, Noshin, & Chen, Hao, & McEnnis, Kathleen (2023). Influence of particle z-potential and experimental procedure on protein corona formation and multicomponent aggregation. AIChE Journal, e18237.
Chen, Hao, & Ai, Yongling, & Gunawardena, Harsha (2023). Rapid Characterization of Antibodies via Automated Flow Injection Coupled with Microdroplet Reactions and Native Mass Spectrometry. Analytical Chemistry, 95, 3340–3348.
Wan, Zhaoxiong, & Yu, Shupei, & Wang, Qi, & Tobia, John, & Chen, Hao, & Li, Zhanjun, & Liu, Xuan, & Zhang, Yuanwei (2022). A BODIPY-Based Far-Red-Absorbing Fluorescent Probe for Hypochlorous Acid Imaging. ChemPhotoChem, e202100250.
Wang, Qi, & Liu, Zhijian, & Liu, Yong, & Chen, Hao (2022). Absolute Quantitation of N-Nitrosamines by Coulometric Mass Spectrometry without Using Standards. J. Am. Soc. Mass Spectrom., 33, 875–884.
Zhang, Wen, & Wang, Qi, & Chen, Hao (2022). Challenges in Characterization of Nanoplastics in the Environment. Front. Environ. Sci. Eng., 16, 11.
Ai, Yongling, & Xu, Jeffrey, & Gunawardena, Harsha P., & Zare, Richard, & Chen, Hao (2022). Investigation of Tryptic Protein Digestion in Microdroplet and in Bulk Solution. J. Am. Soc. Mass Spectrom., 33, 1238–1249.
Wu, Chen, & Chen, Hao, & Li, Mengyan (2022). Rapid Quantitative Analysis and Suspect Screening of Per-and Polyfluorinated Alkyl Substances (PFAS) in Aqueous Film-Forming Foams (AFFFs) and Municipal Wastewater Samples by Nano-ESI-HRMS. Water Research, 219, 118542.
Ai, Yongling, & Gunawardena, Harsha P., & Li, Xuanwen, & Yong, Yong-Ick , & Dewald, Howard, & Chen, Hao (2022). Standard-Free Absolute Quantitation of Antibody Deamidation Degradation and Host Cell Proteins by Coulometric Mass Spectrometry. Anal. Chem., 94, 12490−12499.
Wu, Chen, & Wang, Qi, & Chen, Hao, & Li, Mengyan (2022). Rapid quantitative analysis and suspect screening of per-and polyfluorinated alkyl substances (PFASs) in aqueous film-forming foams (AFFFs) and municipal wastewater samples by Nano-ESI-HRMS. Water Research, 219,
Chen, Hao, & Ai, Yongling, & Zhao, Pengyi, & FNU, Praneeth Ivan Joel (2021). Absolute Quantitation of Tryptophan-Containing Peptides and Amyloid Beta Peptide Fragments by Coulometric Mass Spectrometry. J. Am. Soc. Mass Spectrom., 32, 1771-1779.
Chen, Hao, & Li, Jia, & Zare, Richard (2021). Accelerated oxidation of organic sulfides by microdroplet chemistry. Journal of Organic Chemistry, 86, 5011–5015.
Chen, Hao, & Shi, Xiaodong (2021). Alkyne Trifunctionalization via Divergent Gold Catalysis: Combining p-Acid Activation, Vinyl-Gold Addition and Redox Catalysis. J. Am. Chem. Soc., 143, 4074–4082.
Chen, Hao, & Wang, Qi, & Wang, Qile, & Zheng, Nan, & Zare, Richard, & Pacheco, Carlos , & Mohamed, Yasmine M. , & Zhang, Yuexiang (2021). Electrocatalytic Redox Neutral [3+2] Annulation of N-Cyclopropylanilines and Alkenes. Chemical Science, 12, 969 - 975.
Chen, Hao, & Szostak, Michal (2021). Evaluation of Cyclic Amides as Activating Groups in N–C Bond Cross-Coupling: Discovery of N-Acyl-δ- Valerolactams as Effective Twisted Amide Precursors for Cross-Coupling Reactions. Journal of Organic Chemistry, 86, 10455–10466.
Chen, Hao, & Luo, Kai, & Zare, Richard (2021). Location of carbon-carbon double bonds in unsaturated lipids using microdroplet mass spectrometry. Analyst, 146, 2550-2558.
Chen, Hao, & Zhao, Pengyi, & Zare, Richard, & Gunawardena, Harsha (2021). Microdroplet Ultrafast Reactions Speed Antibody Characterization. Analytical Chemistry, 93, 3997–4005.
Chen, Hao, & Zhong, Xiaoqin, & Zare, Richard (2021). Ultrafast Enzymatic Digestion of Deoxyribonucleic Acid in Aqueous Microdroplets for Sequence Discrimination and Identification. QRB Discovery , 2:e4, 1–8.
Zhao, Pengyi, & Wang, Qi, & Kaur, Manpreet, & Kim, Yong-I., & Dewald, Howard D, & Mozziconacci, Olivier , & Liu, Yong, & Chen, Hao (2020). Absolute Quantitation of Proteins by Coulometric Mass Spectrometry. Analytical Chemistry, in press,
Sambath, Karthik, & Wan, Zhaoxiong , & Wang, Qi, & Chen, Hao, & Zhang, Yuanwei (2020). BODIPY-Based Photoacid Generators (PAGs) for Light-Induced Cationic Polymerization. Organic Letters, in press,
Liu, Chengyuan, & Wang, Qi, & Hivick, Brian E, & Ai, Yongling, & Champagne, Pier, & Pan, Yang, & Chen, Hao (2020). Capture of Electrochemically Generated Fleeting Carbazole Radical Cations and Elucidation of Carbazole Dimerization Mechanism by Mass Spectrometry. Analytical Chemistry, 92(23), 15291--15296.
Song, Xiaowei, & Chen, Hao (2020). Desorption Electrospray Ionization Mass Spectrometry Imaging (DESI-MSI) for Tissue Analysis. Encyclopedia of Analytical Chemistry, in press,
Wang, Jin , & Wei, Chiyu , & Li, Xuming , & Zhao, Pengyi , & Shan, Chuan , & Wojtas, Lukasz , & Chen, Hao, & Shi, Xiaodong (2020). Gold Redox Catalysis with Selenium Cation as Mild Oxidant. Chemistry-An European Journal, in press,
Rahman, M. , & Liu, C., & Bisz, E., & Dziuk, B. , & Lalancette, R. , & Wang, Qi, & Chen, Hao, & Szostak, R. , & Szostak, M. (2020). N-Acyl-Glutarimides: Effect of Glutarimide Ring on the Structures of Fully Perpendicular Twisted Amides and N–C Bond Cross-Coupling. Journal of Organic Chemistry, in press,
Luo, Kai, & Li, Jia , & Cao, Yufei, & Liu, Chengyuan , & Ge, Jun , & Chen, Hao, & Zare, Richard (2020). Reaction of chloroauric acid with histidine in microdroplets yields catalytic Au-(His)2 complex. Chemical Science, in press,
Yuan, Teng , & Zhao, Pengyi, & Teng, Shun , & Yi, Yaping , & Wang, Jin , & Shan, Chuan , & Wojtas, Lukasz , & Jean, Jonathan, & Chen, Hao, & Shi, Xiaodong (2020). Regioselective Crossed Aldol Reactions under Ambient Conditions via Synergistic Gold/Iron Catalysis. Chem (Impact Factor 18.2), in press.
Zhong, Xiaoqin, & Chen, Hao, & Zare, Richard (2020). Ultrafast enzymatic digestion of proteins by microdroplet mass spectrometry. Nature Communications, in press,
Narayanan, Rahul , & Song, Xiaowei, & Chen, Hao, & Zare, Richard (2020). Teflon Spray Ionization Mass Spectrometry. Journal of American Society for Mass Spectrometry, in press,
Zhao, Pengyi I., & Wang, Qi, & Kaur, Manpreet, & Kim, Yong I., & Dewald, Howard, & Mozziconacci, Olivier, & Liu, Yong, & Chen, Hao (2020). Absolute Quantitation of Proteins by Coulometric Mass Spectrometry. Analytical Chemistry, 92, 7877-7883.
Sambath, Karthik, & Wan, Zhaoxiong , & Wang, Qi, & Chen, Hao, & Zhang, Yuanwei (2020). BODIPY-Based Photoacid Generators for Light-Induced Cationic Polymerization. Organic Letters / American Chemical Society, 22(3), 1208-1212.
Zhao, Pengyi, & Zare, Richard N., & Chen, Hao (2019). Absolute Quantitation of Oxidizable Peptides Using Coulometric Mass Spectrometry. J. Am. Soc. Mass Spectrom., 30, 2398-2407.
Ye, Xiaohan, & Zhao, Pengyi, & Zhang, Shuyao , & Zhang, Yanbin, & Wang, Qilin , & Shan, Chuan , & Wojtas, Lukasz , & Guo, Hao, & Chen, Hao, & Shi, Xiaodong (2019). Facilitating Gold Redox Catalysis with Electrochemistry: An Efficient “Chemical-Oxidant-Free” Approach. Angew. Chem. Int. Ed., 58, 17226 –17230 .
Zhao, Pengyi, & Guo, Yong, & Dewald, Howard, & Chen, Hao (2019). Improvements for Absolute Quantitation Using Electrochemical Mass Spectrometry. International Journal of Mass Spectrometry, 443, 41.
Liu, Chengyuan, & Li, Jia, & Chen, Hao, & Zare, Richard N. (2019). Scale-Up of Microdroplet Reactions by Heated Ultrasonic Nebulization. Chemical Science, 10, 9367-9373.
Xu, Chang, & Zheng, Qiuling, & Paterson, Joseph, & Chen, Hao, & Zhao, Pengyi (2019). A novel chemical quantification method using electrochemical mass spectrometry. Journal of American Society for Mass Spectrometry, 30, 685.
Song, X., & Chen, Hao, & Zare, R.N. (2018). Conductive polymer spray ionization mass spectrometry for biofluid analysis. Analytical Chemistry, 90(21), 12878-12885.
Lu, M., & Su, Y., & Zhao, P., & Ye, X., & Cai, Y., & Shi, X., & Masson, E., & Li, F., & Campbell, J.L., & Chen, Hao (2018). Direct evidence for the origin of bis-gold intermediates: Probing gold catalysis with mass spectrometry. Chemistry - A European Journal, 24(9), 2144-2150.
Nshanian, M., & Lakshmanan, R., & Chen, Hao, & Loo, R.R.O., & Loo, J.A. (2018). Enhancing sensitivity of liquid chromatography-mass spectrometry of peptides and proteins using supercharging agents. International Journal of Mass Spectrometry, 427, 157-164.
Wang, J., & Zhang, S., & Xu, C., & Wojtas, L., & Akhmedov, N.G., & Chen, Hao, & Shi, X. (2018). Highly efficient and stereoselective thioallylation of alkynes: Possible gold redox catalysis with no need for a strong oxidant. Angewandte Chemie - International Edition, 57(23), 6915-6920.
Zheng, Q., & Tian, Y., & Ruan, X., & Chen, Hao, & Wu, X., & Xu, X., & Wang, G., & Hao, H., & Ye, H. (2018). Probing specific ligand-protein interactions by native-denatured exchange mass spectrometry. Analytica Chimica Acta, 1036, 58-65.
Chen, Z., & Jiang, Z., & Chen, N., & Shi, Q., & Tong, L., & Kong, F., & Cheng, X., & Chen, Hao, & Wang, C., & Tang, B. (2018). Target discovery of ebselen with a biotinylated probe. Chemical Communications, 54(68), 9506-9509.
Liu, P., & Zhao, P., & Graham Cooks, R., & Chen, Hao (2017). Atmospheric pressure neutral reionization mass spectrometry for structural analysis. Chemical Science, 8(9), 6499-6507.
Cai, Y., & Wang, J., & Zhang, Y., & Li, Z., & Hu, D., & Zheng, N., & Chen, Hao (2017). Detection of fleeting amine radical cations and elucidation of chain processes in visible-light-mediated [3 + 2] annulation by online mass spectrometric techniques. Journal of the American Chemical Society, 139(35), 12259-12266.
Cheng, S., & Wu, Q., & Xiao, H., & Chen, Hao (2017). Online monitoring of enzymatic reactions using time-resolved desorption electrospray ionization mass spectrometry. Analytical Chemistry, 89(4), 2338-2344.
Cheng, S., & Wu, Q., & Dewald, H.D., & Chen, Hao (2017). Online monitoring of methanol electro-oxidation reactions by ambient mass spectrometry. Journal of the American Society for Mass Spectrometry, 28(6), 1005-1012.
Wu, Q., & Cheng, S., & Chen, Hao, & Wang, C. (2017). ZIF-67 Templated synthesis of nanoporous carbon as an efficient adsorbent for preconcentration of flunitrazepam from beverage samples. Food Analytical Methods, 10(8), 2772-2780.
Cai, Y., & Liu, P., & Held, M.A., & Dewald, H.D., & Chen, Hao (2016). Coupling electrochemistry with probe electrospray ionization mass spectrometry. ChemPhysChem, 17(8), 1104-1108.
Zheng, Q., & Chen, Hao (2016). Development and applications of liquid sample desorption electrospray ionization mass spectrometry. Annual Review of Analytical Chemistry, 9, 411-448.
Wu, Q., & Cheng, S., & Li, Z., & Chen, Hao (2016). Highly sensitive mass spectrometric detection of flunitrazepam using magnetic graphene framework enrichment. Analytical Methods, 8(32), 6168-6175.
Li, Z., & Zhang, S., & Cai, Y., & Wu, Q., & Chen, Hao (2016). Hollow fiber-based solid-liquid phase microextraction combined with theta capillary electrospray ionization mass spectrometry for sensitive and accurate analysis of methamphetamine. Analytical Methods, 8(43), 7800-7807.
Peng, H., & Cai, R., & Xu, C., & Chen, Hao, & Shi, X. (2016). Nucleophile promoted gold redox catalysis with diazonium salts: C-Br, C-S and C-P bond formation through catalytic Sandmeyer coupling. Chemical Science, 7(9), 6190-6196.
Brown, T.A., & Hosseini-Nassab, N., & Chen, Hao, & Zare, R.N. (2016). Observation of electrochemically generated nitrenium ions by desorption electrospray ionization mass spectrometry. Chemical Science, 7(1), 329-332.
Ding, Z., & Jiang, M., & Chen, Hao, & Jin, Z., & Zhou, Mengchu (2016). Petri net based test case generation for evolved specification. Science China Information Sciences, 59(8),
Zheng, Q., & Zhang, H., & Wu, S., & Chen, Hao (2016). Probing protein 3D structures and conformational changes using electrochemistry-assisted isotope labeling cross-linking mass spectrometry. Journal of the American Society for Mass Spectrometry, 27(5), 864-875.
Ye, X., & Xu, C., & Wojtas, L., & Akhmedov, N.G., & Chen, Hao, & Shi, X. (2016). Silver-free palladium-catalyzed sp3 and sp2 C-H alkynylation promoted by a 1,2,3-triazole amine directing group. Organic Letters, 18(12), 2970-2973.
Li, L., & Wang, X., & Li, Q., & Liu, P., & Xu, K., & Chen, Hao, & Tang, B. (2015). An accurate mass spectrometric approach for the simultaneous comparison of GSH, Cys, and Hcy in L02 cells and HepG2 cells using new NPSP isotope probes. Chemical Communications, 51(56), 11317-11320.
Zheng, Q., & Liu, Y., & Chen, Q., & Hu, M., & Helmy, R., & Sherer, E.C., & Welch, C.J., & Chen, Hao (2015). Capture of reactive monophosphine-ligated palladium(0) intermediates by mass spectrometry. Journal of the American Chemical Society, 137(44), 14035-14038.
Brown, T.A., & Chen, Hao, & Zare, R.N. (2015). Detection of the short-lived radical cation intermediate in the electrooxidation of N,N-Dimethylaniline by mass spectrometry. Angewandte Chemie - International Edition, 54(38), 11183-11185.
Cheng, S., & Wang, J., & Cai, Y., & Loo, J.A., & Chen, Hao (2015). Enhancing performance of liquid sample desorption electrospray ionization mass spectrometry using trap and capillary columns. International Journal of Mass Spectrometry, 392, 73-79.
Kong, F., & Hu, B., & Gao, Y., & Xu, K., & Pan, X., & Huang, F., & Zheng, Q., & Chen, Hao, & Tang, B. (2015). Fluorescence imaging of selenol in HepG2 cell apoptosis induced by Na2SeO3. Chemical Communications, 51(15), 3102-3105.
Brown, T.A., & Chen, Hao, & Zare, R.N. (2015). Identification of fleeting electrochemical reaction intermediates using desorption electrospray ionization mass spectrometry. Journal of the American Chemical Society, 137(23), 7274-7277.
Cai, Y., & Zheng, Q., & Liu, Y., & Helmy, R., & Loo, J.A., & Chen, Hao (2015). Integration of electrochemistry with ultraperformance liquid chromatography/mass spectrometry. European Journal of Mass Spectrometry, 21(3), 341-351.
Cai, R., & Lu, M., & Aguilera, E.Y., & Xi, Y., & Akhmedov, N.G., & Petersen, J.L., & Chen, Hao, & Shi, X. (2015). Ligand-assisted gold-catalyzed cross-coupling with aryldiazonium salts: Redox gold catalysis without an external oxidant. Angewandte Chemie - International Edition, 54(30), 8772-8776.
Liu, P., & Cooks, R.G., & Chen, Hao (2015). Nuclear magnetic resonance structure elucidation of peptide b2 ions. Angewandte Chemie - International Edition, 54(5), 1547-1550.
Liu, P., & Zheng, Q., & Dewald, H.D., & Zhou, R., & Chen, Hao (2015). The study of electrochemistry with ambient mass spectrometry. TrAC - Trends in Analytical Chemistry, 70, 20-30.
Cai, Y., & Adams, D., & Chen, Hao (2014). A new splitting method for both analytical and preparative LC/MS. Journal of the American Society for Mass Spectrometry, 25(2), 286-292.
Cai, Y., & Liu, Y., & Helmy, R., & Chen, Hao (2014). Coupling of ultrafast LC with mass spectrometry by DESI. Journal of the American Society for Mass Spectrometry, 25(10), 1820-1823.
Zheng, Q., & Zhang, H., & Tong, L., & Wu, S., & Chen, Hao (2014). Cross-linking electrochemical mass spectrometry for probing protein three-dimensional structures. Analytical Chemistry, 86(18), 8983-8991.
Liu, P., & Forni, A., & Chen, Hao (2014). Development of solvent-free ambient mass spectrometry for green chemistry applications. Analytical Chemistry, 86(8), 4024-4032.
Su, Y., & Lu, M., & Dong, B., & Chen, Hao, & Shi, X. (2014). Silver-catalyzed alkyne activation: The surprising ligand effect. Advanced Synthesis and Catalysis, 356(4), 692-696.
Pan, N., & Liu, P., & Cui, W., & Tang, B., & Shi, J., & Chen, Hao (2013). Highly efficient ionization of phosphopeptides at low pH by desorption electrospray ionization mass spectrometry. Analyst, 138(5), 1321-1324.
Zheng, Q., & Zhang, H., & Chen, Hao (2013). Integration of online digestion and electrolytic reduction with mass spectrometry for rapid disulfide-containing protein structural analysis. International Journal of Mass Spectrometry, 353, 84-92.
Liu, P., & Zhang, J., & Ferguson, C.N., & Chen, Hao, & Loo, J.A. (2013). Measuring protein-ligand interactions using liquid sample desorption electrospray ionization mass spectrometry. Analytical Chemistry, 85(24), 11966-11972.
Lu, M., & Campbell, J.L., & Chauhan, R., & Grapperhaus, C.A., & Chen, Hao (2013). Probing the reactivity and radical nature of oxidized transition metal-thiolate complexes by mass spectrometry. Journal of the American Society for Mass Spectrometry, 24(4), 502-512.
Liu, P., & Lu, M., & Zheng, Q., & Zhang, Y., & Dewald, H.D., & Chen, Hao (2013). Recent advances of electrochemical mass spectrometry. Analyst, 138(19), 5519-5539.
Weldy, E., & Wolff, C., & Miao, Z., & Chen, Hao (2013). Selective and sensitive detection of chromium(VI) in waters using electrospray ionization mass spectrometry. Science and Justice, 53(3), 293-300.
Zhang, Y., & Cui, W., & Zhang, H., & Dewald, H.D., & Chen, Hao (2012). Electrochemistry-assisted top-down characterization of disulfide-containing proteins. Analytical Chemistry, 84(8), 3838-3842.
Wang, Z., & Zhang, Y., & Zhang, H., & Harrington, P.B., & Chen, Hao (2012). Fast and selective modification of thiol proteins/peptides by N-(phenylseleno) phthalimide. Journal of the American Society for Mass Spectrometry, 23(3), 520-529.
Lu, M., & Wolff, C., & Cui, W., & Chen, Hao (2012). Investigation of some biologically relevant redox reactions using electrochemical mass spectrometry interfaced by desorption electrospray ionization. Analytical and Bioanalytical Chemistry, 403(2), 355-365.
D'Aloise, P., & Chen, Hao (2012). Rapid determination of flunitrazepam in alcoholic beverages by desorption electrospray ionization-mass spectrometry. Science and Justice, 52(1), 2-8.
Liu, Y., & Miao, Z., & Lakshmanan, R., & Loo, R.R.O., & Loo, J.A., & Chen, Hao (2012). Signal and charge enhancement for protein analysis by liquid chromatography-mass spectrometry with desorption electrospray ionization. International Journal of Mass Spectrometry, 325-327, 161-166.
Chen, Z., & Li, Q., & Sun, Q., & Chen, Hao, & Wang, X., & Li, N., & Yin, M., & Xie, Y., & Li, H., & Tang, B. (2012). Simultaneous determination of reactive oxygen and nitrogen species in mitochondrial compartments of apoptotic HepG2 cells and PC12 cells based on microchip electrophoresis-laser-induced fluorescence. Analytical Chemistry, 84(11), 4687-4694.
Liu, P., & Lanekoff, I.T., & Laskin, J., & Dewald, H.D., & Chen, Hao (2012). Study of electrochemical reactions using nanospray desorption electrospray ionization mass spectrometry. Analytical Chemistry, 84(13), 5737-5743.
Zhang, Y., & Yuan, Z., & Dewald, H.D., & Chen, Hao (2011). Coupling of liquid chromatography with mass spectrometry by desorption electrospray ionization (DESI). Chemical Communications, 47(14), 4171-4173.
Sun, X., & Miao, Z., & Yuan, Z., & Harrington, P.D.B., & Colla, J., & Chen, Hao (2011). Coupling of single droplet micro-extraction with desorption electrospray ionization-mass spectrometry. International Journal of Mass Spectrometry, 301(1-3), 102-108.
Miao, Z., & Chen, Hao, & Liu, P., & Liu, Y. (2011). Development of submillisecond time-resolved mass spectrometry using desorption electrospray ionization. Analytical Chemistry, 83(11), 3994-3997.
Ferguson, C.N., & Benchaar, S.A., & Miao, Z., & Loo, J.A., & Chen, Hao (2011). Direct ionization of large proteins and protein complexes by desorption electrospray ionization-mass spectrometry. Analytical Chemistry, 83(17), 6468-6473.
Zhang, Y., & Dewald, H.D., & Chen, Hao (2011). Online mass spectrometric analysis of proteins/peptides following electrolytic cleavage of disulfide bonds. Journal of Proteome Research, 10(3), 1293-1304.
Zhang, Y., & Zhang, H., & Cui, W., & Chen, Hao (2011). Tandem MS analysis of selenamide-derivatized peptide ions. Journal of the American Society for Mass Spectrometry, 22(9), 1610-1621.
Zhang, Y., & Chen, Hao (2010). Detection of saccharides by reactive desorption electrospray ionization (DESI) using modified phenylboronic acids. International Journal of Mass Spectrometry, 289(2-3), 98-107.
Xu, K., & Zhang, Y., & Tang, B., & Laskin, J., & Roach, P.J., & Chen, Hao (2010). Study of highly selective and efficient thiol derivatization using selenium reagents by mass spectrometry. Analytical Chemistry, 82(16), 6926-6932.
Gau, B.C., & Chen, Hao, & Zhang, Y., & Gross, M.L. (2010). Sulfate radical anion as a new reagent for fast photochemical oxidation of proteins. Analytical Chemistry, 82(18), 7821-7827.
Miao, Z., & Wu, S., & Chen, Hao (2010). The study of protein conformation in solution via direct sampling by desorption electrospray ionization mass spectrometry. Journal of the American Society for Mass Spectrometry, 21(10), 1730-1736.
Miao, Z., & Chen, Hao (2009). Direct analysis of liquid samples by desorption electrospray ionization-mass spectrometry (DESI-MS). Journal of the American Society for Mass Spectrometry, 20(1), 10-19.
Li, J., & Dewald, H.D., & Chen, Hao (2009). Online coupling of electrochemical reactions with liquid sample desorption electrospray ionization-mass spectrometry. Analytical Chemistry, 81(23), 9716-9722.
Lu, W., & László, C.F., & Miao, Z., & Chen, Hao, & Wu, S. (2009). The role of nitric-oxide synthase in the regulation of UVB light-induced phosphorylation of the α subunit of eukaryotic initiation factor 2. Journal of Biological Chemistry, 284(36), 24281-24288.
Eberlin, L.S., & Xia, Y., & Chen, Hao, & Cooks, R.G. (2008). Atmospheric pressure thermal dissociation of phospho- and sulfopeptides. Journal of the American Society for Mass Spectrometry, 19(12), 1897-1905.
Cotte-Rodríguez, I., & Hernández-Soto, H., & Chen, Hao, & Cooks, R.G. (2008). In situ trace detection of peroxide explosives by desorption electrospray ionization and desorption atmospheric pressure chemical ionization. Analytical Chemistry, 80(5), 1512-1519.
Chen, Hao, & Eberlin, L.S., & Nefliu, M., & Augusti, R., & Cooks, R.G. (2008). Organic reactions of ionic intermediates promoted by atmospheric-pressure thermal activation. Angewandte Chemie - International Edition, 47(18), 3422-3425.
Peng, W.-P., & Goodwin, M.P., & Chen, Hao, & Cooks, R.G., & Wilker, J. (2008). Thermal formation of mixed-metal inorganic complexes at atmospheric pressure. Rapid Communications in Mass Spectrometry, 22(22), 3540-3548.
Chen, Hao, & Zuo, Yuegang (2007). Identification of flavonol glycosides in American cranberry fruit. Food Chemistry, 101, 1357-1364.
Chen, Hao, & Eberlin, L.S., & Cooks, R.G. (2007). Neutral fragment mass spectra via ambient thermal dissociation of peptide and protein ions. Journal of the American Chemical Society, 129(18), 5880-5886.
Huang, G., & Chen, Hao, & Zhang, X., & Cooks, R.G., & Ouyang, Z. (2007). Rapid screening of anabolic steroids in urine by reactive desorption electrospray ionization. Analytical Chemistry, 79(21), 8327-8332.
Augusti, R., & Chen, Hao, & Eberlin, L.S., & Nefliu, M., & Cooks, R.G. (2006). Atmospheric pressure Eberlin transacetalization reactions in the heterogeneous liquid/gas phase. International Journal of Mass Spectrometry, 253(3), 281-287.
Chen, Hao, & Cotte-Rodríguez, I., & Cooks, R.G. (2006). cis-Diol functional group recognition by reactive desorption electrospray ionization (DESI). Chemical Communications, 6(6), 597-599.
Goebbert, Daniel J, & Chen, Hao, & Wenthold, Paul G (2006). Collision‐induced dissociation studies of protonated ether—(H2O)n (n = 1–3) clusters. Journal of Mass Spectrometry, 41, 242-247.
Deng, Yiwei, & Zhang, Kai, & Chen, Hao, & Wu, Taixing, & Krzyaniak, Metthew, & Wellons, Amina, & Bolla, Dawn, & Douglas, Kenneth, & Zuo, Yuegang (2006). Iron-catalyzed photochemical transformation of benzoic acid in atmospheric liquids: Product identification and reaction mechanisms. Atmospheric Environment, 40, 3665-3676.
Cooks, R.G., & Chen, Hao, & Eberlin, M.N., & Zheng, X., & Tao, W.A. (2006). Polar acetalization and transacetalization in the gas phase: The Eberlin reaction. Chemical Reviews, 106(1), 188-211.
Cotte-Rodríguez, I., & Chen, Hao, & Cooks, R.G. (2006). Rapid trace detection of triacetone triperoxide (TATP) by complexation reactions during desorption electrospray ionization. Chemical Communications(9), 953-955.
Chen, Hao, & Ouyang, Z., & Cooks, R.G. (2006). Thermal production and reactions of organic ions at atmospheric pressure. Angewandte Chemie - International Edition, 45(22), 3656-3660.
Popov, I.A., & Chen, Hao, & Kharybin, O.N., & Nikolaev, E.N., & Cooks, R.G. (2005). Detection of explosives on solid surfaces by thermal desorption and ambient ion/molecule reactions. Chemical Communications(15), 1953-1955.
Chen, Hao, & Cooks, R.G., & Meurer, E.C., & Eberlin, M.N. (2005). Hydrogen/chlorine exchange reactions of gaseous carbanions. Journal of the American Society for Mass Spectrometry, 16(12), 2045-2051.
Chen, Hao, & Xu, R., & Chen, Hao, & Cooks, R.G., & Ouyang, Z. (2005). Ion/molecule reactions in a miniature RIT mass spectrometer. Journal of Mass Spectrometry, 40(11), 1403-1411.
Chen, Hao, & Justes, D.R., & Cooks, R.G. (2005). Proton affinities of N-heterocyclic carbene super bases. Organic Letters, 7(18), 3949-3952.
Song, Y., & Chen, Hao, & Cooks, R.G. (2005). Reactivity of acetonyl anion with nitroaromatics: An atmospheric pressure chemical ionization study. Rapid Communications in Mass Spectrometry, 19(23), 3493-3499.
Bagheri, H., & Chen, Hao, & Cooks, R.G. (2004). Chiral recognition by proton transfer reactions with optically active amines and alcohols. Chemical Communications(23), 2740-2741.
Augusti, R., & Turowski, M., & Chen, Hao, & Cooks, R.G. (2004). Dissociation of ionized benzophenones investigated by the kinetic method: Effective temperature, steric effects and gas-phase CO+. affinities of phenyl radicals. Journal of Mass Spectrometry, 39(5), 558-564.
Augusti, R., & Augusti, D.V., & Chen, Hao, & Cooks, R.G. (2004). Gas-phase halide affinity of aliphatic alcohols estimated by the kinetic method. European Journal of Mass Spectrometry, 10(6), 847-855.
Meurer, E.C., & Chen, Hao, & Riter, L., & Cotte-Rodriguez, I., & Eberlin, M.N., & Cooks, R.G. (2004). Gas-phase reactions for selective detection of the explosives TNT and RDX. Chemical Communications, 4(1), 40-41.
Chen, Hao, & Chen, Hao, & Cooks, R.G., & Bagheri, H. (2004). Generation of arylnitrenium ions by nitro-reduction and gas-phase synthesis of N-heterocycles. Journal of the American Society for Mass Spectrometry, 15(11), 1675-1688.
Meurer, E.C., & Chen, Hao, & Riter, L.S., & Cooks, R.G., & Eberlin, M.N. (2004). Meerwein reaction of phosphonium ions with epoxides and thioepoxides in the gas phase. Journal of the American Society for Mass Spectrometry, 15(3), 398-405.
Chen, Hao, & Chen, Hao, & Cooks, R.G. (2004). Meisenheimer complexes bonded at carbon and at oxygen. Journal of the American Society for Mass Spectrometry, 15(7), 998-1004.
Chen, Hao, & Zheng, X., & Yang, P., & Cooks, R.G. (2004). Reduction of nitroaromatics to arylnitrenium ions by vinyl halide cations. Chemical Communications, 10(6), 688-689.
Riter, Leah S, & Meurer, Eduardo C, & Handberg, Eric S, & Laughlin, Brian C, & Chen, Hao, & Patterson, Garth E, & Cooks, R Graham (2003). Ion/molecule reactions performed in a miniature cylindrical ion trap mass spectrometer. Analyst, 28, 1112-1118.
Chen, Hao, & Zheng, X., & Cooks, R.G. (2003). Ketalization of phosphonium ions by 1,4-dioxane: Selective detection of the chemical warfare agent simulant DMMP in mixtures using ion/molecule reactions. Journal of the American Society for Mass Spectrometry, 14(3), 182-188.
Zuo, Yuegang, & Chen, Hao (2003). Simultaneous determination of sulfite, sulfate, and hydroxymethanesulfonate in atmospheric waters by ion-pair HPLC technique. Talenta, 59, 875-881.
Zuo, Yuegang, & Chen, Hao, & Deng, Yiwei (2002). Simultaneous determination of catechins, caffeine and gallic acids in green, Oolong, black and pu-erh teas using HPLC with a photodiode array detector. Talenta, 57, 307-316.
Yang, Yonggang, & Chen, Hao, & Tang, Geng, & Wen, Jianxun (2002). Synthesis and mesomorphic properties of several series of fluorinated ester liquid crystals. Liquid Crystals, 29, 255-261.
Yang, Yonggang, & Chen, Hao, & Tang, Geng, & Wen, Jianxun (2002). Synthesis and mesomorphic properties of some fluorinated benzoate liquid crystals. Molecular Crystals and Liquid Crystals, 373, 1-15.
Chen, Hao, & Zuo, Yuegang, & Deng, Yiwei (2001). Separation and determination of flavonoids and other phenolic compounds in cranberry juice by high-performance liquid chromatography. Journal of Chromatography A, 913, 387-395.
Wen, Jianxun, & Chen, Hao, & Shen, Yuehai (1999). The first series of ferroelectric steroidal fluorinated liquid crystals. Liquid Crystals, 26, 1833-1834.
Bhattarai, Matrika , & Wang, Qi , & Hassan, Md. Tanim-Al , & Hussain, Zawar , & Chen, Hao, & Faik, Ahmed (2024). New insights on beta-glycan synthases using in vitro GT-array (i-GT-ray) platform. Plant Physiology and Biochemistry, in press,
Hassan, Md. Tanim-Al, & Chen, Xingzhi , & FNU, Praneeth Ivan Joel , & Osonga, Francis J. , & Sadik, Omowunmi A. , & Li, Mengyan , & Chen, Hao (2024). Rapid Detection of Per- and Polyfluoroalkyl Substances (PFAS) Using Paper Spray-Based Mass Spectrometry. Journal of Hazardous Materials, 465, 133366 .
Bhattarai, Matrika , & Wang, Qi , & Javaid, Tasleem , & Venkataraghavan, Akshayaa , & Hassan, Md Tanim-Al , & O’Neil, Malcolm , & Tan, Li , & Chen, Hao, & Faik, Ahmed (2024). Streamlining enzyme assays of glycosyltransferases activity using in vitro GT-array (i-GT-ray) platform: Application to family GT37 fucosyltransferases. Journal of Biological Chemistry, 300, 105734.
Wu, Chen, & Goodrow, Sandra, & Chen, Hao, & Li, Mengyan (2024). Distinctive biotransformation and biodefluorination of 6:2 versus 5:3 fluorotelomer carboxylic acids by municipal activated sludge. Water Research, 254,
Hassan, Md Tanim, & Chen, Xingzhi, & Fnu, Praneeth Ivan, & Osonga, Francis J., & Sadik, Omowunmi, & Li, Mengyan, & Chen, Hao (2024). Rapid detection of per- and polyfluoroalkyl substances (PFAS) using paper spray-based mass spectrometry. Journal of Hazardous Materials, 465,
Chen, Hao, & Wang, Chun (2023). Converting waste expanded polystyrene into higher-value-added hyper-crosslinked porous polymer for rapid and high-efficient adsorption of aflatoxins. Journal of Cleaner Production, 408, 137102.
Wan, Zhaoxiong, & Yu, Shupei, & Wang, Qi, & Sambath, Karthik, & Harty, Roshena, & Liu, Xiangshan, & Chen, Hao, & Wang, Chen, & Liu, Xuan, & Zhang, Yuanwei (2023). Far-red BODIPY-based oxime esters: photo-uncaging and drug delivery. Journal of Materials Chemistry B, 11(41), 9889--9893.
Yu, Shupei , & Reddy, Ojasvita , & Abaci, Alperen , & Ai, Yongling , & Li, Yanmei , & Chen, Hao, & Guvendiran, Murat , & Belfield, Kevin , & Zhang, Yuanwei (2023). Novel BODIPY-based photobase generators for photo-induced polymerization. ACS Applied Materials & Interfaces, 15, 45281–45289.
Li, Yanmei , & Castañeda-Bagatella, Diana M. , & Kakkad, Dhyeyi , & Ai, Yongling , & Chen, Hao, & Champagne, Pier Alexandre (2023). Synthetic and mechanistic study on the conjugate isothiocyanation of enones with trimethylsilyl isothiocyanate . Organic & Biomolecular Chemistry, 21, 9583-9590.
Li, Yanmei, & Castaneda Bagatella, Diana Marlén, & Kakkad, Dhyeyi, & Ai, Yongling, & Chen, Hao, & Champagne, Pier Alexandre (2023). Synthetic and mechanistic study on the conjugate isothiocyanation of enones with trimethylsilyl isothiocyanate. Organic & Biomolecular Chemistry, 21, 9583-9590.
Gewering, Theresa , & Waghray, Deepali , & Parey, Kristian , & Jung, Hendrik , & Tran, Nghi N.B. , & Zapata, Joel , & Zhao, Pengyi , & Chen, Hao, & Januliene, Dovile , & Hummer, Gerhard , & Urbatsch, Ina L. , & Moeller, Arne , & Zhang, Qinghai (2023). Tracing the substrate translocation mechanism in P-glycoprotein. eLife, 12, RP90174 .
Shen, Yucong, & Shih, Frank Y., & Chen, Hao (2023). Drug toxicity prediction by machine learning approaches. Pattern Recognition and Artificial Intelligence, 37(8), 2351013 (14 pages).
López Ruiz, Aida, & Xiao, Mengyuan, & Sathya, Asmitha, & Piccininni, Nicole, & Liu, Guangliang, & Siddiq, Noshin, & Chen, Hao, & McEnnis, Kathleen (2023). Influence of particle z-potential and experimental procedure on protein corona formation and multicomponent aggregation. AIChE Journal, e18237.
Chen, Hao, & Ai, Yongling, & Gunawardena, Harsha (2023). Rapid Characterization of Antibodies via Automated Flow Injection Coupled with Microdroplet Reactions and Native Mass Spectrometry. Analytical Chemistry, 95, 3340–3348.
Wan, Zhaoxiong, & Yu, Shupei, & Wang, Qi, & Tobia, John, & Chen, Hao, & Li, Zhanjun, & Liu, Xuan, & Zhang, Yuanwei (2022). A BODIPY-Based Far-Red-Absorbing Fluorescent Probe for Hypochlorous Acid Imaging. ChemPhotoChem, e202100250.
Wang, Qi, & Liu, Zhijian, & Liu, Yong, & Chen, Hao (2022). Absolute Quantitation of N-Nitrosamines by Coulometric Mass Spectrometry without Using Standards. J. Am. Soc. Mass Spectrom., 33, 875–884.
Zhang, Wen, & Wang, Qi, & Chen, Hao (2022). Challenges in Characterization of Nanoplastics in the Environment. Front. Environ. Sci. Eng., 16, 11.
Ai, Yongling, & Xu, Jeffrey, & Gunawardena, Harsha P., & Zare, Richard, & Chen, Hao (2022). Investigation of Tryptic Protein Digestion in Microdroplet and in Bulk Solution. J. Am. Soc. Mass Spectrom., 33, 1238–1249.
Wu, Chen, & Chen, Hao, & Li, Mengyan (2022). Rapid Quantitative Analysis and Suspect Screening of Per-and Polyfluorinated Alkyl Substances (PFAS) in Aqueous Film-Forming Foams (AFFFs) and Municipal Wastewater Samples by Nano-ESI-HRMS. Water Research, 219, 118542.
Ai, Yongling, & Gunawardena, Harsha P., & Li, Xuanwen, & Yong, Yong-Ick , & Dewald, Howard, & Chen, Hao (2022). Standard-Free Absolute Quantitation of Antibody Deamidation Degradation and Host Cell Proteins by Coulometric Mass Spectrometry. Anal. Chem., 94, 12490−12499.
Wu, Chen, & Wang, Qi, & Chen, Hao, & Li, Mengyan (2022). Rapid quantitative analysis and suspect screening of per-and polyfluorinated alkyl substances (PFASs) in aqueous film-forming foams (AFFFs) and municipal wastewater samples by Nano-ESI-HRMS. Water Research, 219,
Chen, Hao, & Ai, Yongling, & Zhao, Pengyi, & FNU, Praneeth Ivan Joel (2021). Absolute Quantitation of Tryptophan-Containing Peptides and Amyloid Beta Peptide Fragments by Coulometric Mass Spectrometry. J. Am. Soc. Mass Spectrom., 32, 1771-1779.
Chen, Hao, & Li, Jia, & Zare, Richard (2021). Accelerated oxidation of organic sulfides by microdroplet chemistry. Journal of Organic Chemistry, 86, 5011–5015.
Chen, Hao, & Shi, Xiaodong (2021). Alkyne Trifunctionalization via Divergent Gold Catalysis: Combining p-Acid Activation, Vinyl-Gold Addition and Redox Catalysis. J. Am. Chem. Soc., 143, 4074–4082.
Chen, Hao, & Wang, Qi, & Wang, Qile, & Zheng, Nan, & Zare, Richard, & Pacheco, Carlos , & Mohamed, Yasmine M. , & Zhang, Yuexiang (2021). Electrocatalytic Redox Neutral [3+2] Annulation of N-Cyclopropylanilines and Alkenes. Chemical Science, 12, 969 - 975.
Chen, Hao, & Szostak, Michal (2021). Evaluation of Cyclic Amides as Activating Groups in N–C Bond Cross-Coupling: Discovery of N-Acyl-δ- Valerolactams as Effective Twisted Amide Precursors for Cross-Coupling Reactions. Journal of Organic Chemistry, 86, 10455–10466.
Chen, Hao, & Luo, Kai, & Zare, Richard (2021). Location of carbon-carbon double bonds in unsaturated lipids using microdroplet mass spectrometry. Analyst, 146, 2550-2558.
Chen, Hao, & Zhao, Pengyi, & Zare, Richard, & Gunawardena, Harsha (2021). Microdroplet Ultrafast Reactions Speed Antibody Characterization. Analytical Chemistry, 93, 3997–4005.
Chen, Hao, & Zhong, Xiaoqin, & Zare, Richard (2021). Ultrafast Enzymatic Digestion of Deoxyribonucleic Acid in Aqueous Microdroplets for Sequence Discrimination and Identification. QRB Discovery , 2:e4, 1–8.
Zhao, Pengyi, & Wang, Qi, & Kaur, Manpreet, & Kim, Yong-I., & Dewald, Howard D, & Mozziconacci, Olivier , & Liu, Yong, & Chen, Hao (2020). Absolute Quantitation of Proteins by Coulometric Mass Spectrometry. Analytical Chemistry, in press,
Sambath, Karthik, & Wan, Zhaoxiong , & Wang, Qi, & Chen, Hao, & Zhang, Yuanwei (2020). BODIPY-Based Photoacid Generators (PAGs) for Light-Induced Cationic Polymerization. Organic Letters, in press,
Liu, Chengyuan, & Wang, Qi, & Hivick, Brian E, & Ai, Yongling, & Champagne, Pier, & Pan, Yang, & Chen, Hao (2020). Capture of Electrochemically Generated Fleeting Carbazole Radical Cations and Elucidation of Carbazole Dimerization Mechanism by Mass Spectrometry. Analytical Chemistry, 92(23), 15291--15296.
Song, Xiaowei, & Chen, Hao (2020). Desorption Electrospray Ionization Mass Spectrometry Imaging (DESI-MSI) for Tissue Analysis. Encyclopedia of Analytical Chemistry, in press,
Wang, Jin , & Wei, Chiyu , & Li, Xuming , & Zhao, Pengyi , & Shan, Chuan , & Wojtas, Lukasz , & Chen, Hao, & Shi, Xiaodong (2020). Gold Redox Catalysis with Selenium Cation as Mild Oxidant. Chemistry-An European Journal, in press,
Rahman, M. , & Liu, C., & Bisz, E., & Dziuk, B. , & Lalancette, R. , & Wang, Qi, & Chen, Hao, & Szostak, R. , & Szostak, M. (2020). N-Acyl-Glutarimides: Effect of Glutarimide Ring on the Structures of Fully Perpendicular Twisted Amides and N–C Bond Cross-Coupling. Journal of Organic Chemistry, in press,
Luo, Kai, & Li, Jia , & Cao, Yufei, & Liu, Chengyuan , & Ge, Jun , & Chen, Hao, & Zare, Richard (2020). Reaction of chloroauric acid with histidine in microdroplets yields catalytic Au-(His)2 complex. Chemical Science, in press,
Yuan, Teng , & Zhao, Pengyi, & Teng, Shun , & Yi, Yaping , & Wang, Jin , & Shan, Chuan , & Wojtas, Lukasz , & Jean, Jonathan, & Chen, Hao, & Shi, Xiaodong (2020). Regioselective Crossed Aldol Reactions under Ambient Conditions via Synergistic Gold/Iron Catalysis. Chem (Impact Factor 18.2), in press.
Zhong, Xiaoqin, & Chen, Hao, & Zare, Richard (2020). Ultrafast enzymatic digestion of proteins by microdroplet mass spectrometry. Nature Communications, in press,
Narayanan, Rahul , & Song, Xiaowei, & Chen, Hao, & Zare, Richard (2020). Teflon Spray Ionization Mass Spectrometry. Journal of American Society for Mass Spectrometry, in press,
Zhao, Pengyi I., & Wang, Qi, & Kaur, Manpreet, & Kim, Yong I., & Dewald, Howard, & Mozziconacci, Olivier, & Liu, Yong, & Chen, Hao (2020). Absolute Quantitation of Proteins by Coulometric Mass Spectrometry. Analytical Chemistry, 92, 7877-7883.
Sambath, Karthik, & Wan, Zhaoxiong , & Wang, Qi, & Chen, Hao, & Zhang, Yuanwei (2020). BODIPY-Based Photoacid Generators for Light-Induced Cationic Polymerization. Organic Letters / American Chemical Society, 22(3), 1208-1212.
Zhao, Pengyi, & Zare, Richard N., & Chen, Hao (2019). Absolute Quantitation of Oxidizable Peptides Using Coulometric Mass Spectrometry. J. Am. Soc. Mass Spectrom., 30, 2398-2407.
Ye, Xiaohan, & Zhao, Pengyi, & Zhang, Shuyao , & Zhang, Yanbin, & Wang, Qilin , & Shan, Chuan , & Wojtas, Lukasz , & Guo, Hao, & Chen, Hao, & Shi, Xiaodong (2019). Facilitating Gold Redox Catalysis with Electrochemistry: An Efficient “Chemical-Oxidant-Free” Approach. Angew. Chem. Int. Ed., 58, 17226 –17230 .
Zhao, Pengyi, & Guo, Yong, & Dewald, Howard, & Chen, Hao (2019). Improvements for Absolute Quantitation Using Electrochemical Mass Spectrometry. International Journal of Mass Spectrometry, 443, 41.
Liu, Chengyuan, & Li, Jia, & Chen, Hao, & Zare, Richard N. (2019). Scale-Up of Microdroplet Reactions by Heated Ultrasonic Nebulization. Chemical Science, 10, 9367-9373.
Xu, Chang, & Zheng, Qiuling, & Paterson, Joseph, & Chen, Hao, & Zhao, Pengyi (2019). A novel chemical quantification method using electrochemical mass spectrometry. Journal of American Society for Mass Spectrometry, 30, 685.
Song, X., & Chen, Hao, & Zare, R.N. (2018). Conductive polymer spray ionization mass spectrometry for biofluid analysis. Analytical Chemistry, 90(21), 12878-12885.
Lu, M., & Su, Y., & Zhao, P., & Ye, X., & Cai, Y., & Shi, X., & Masson, E., & Li, F., & Campbell, J.L., & Chen, Hao (2018). Direct evidence for the origin of bis-gold intermediates: Probing gold catalysis with mass spectrometry. Chemistry - A European Journal, 24(9), 2144-2150.
Nshanian, M., & Lakshmanan, R., & Chen, Hao, & Loo, R.R.O., & Loo, J.A. (2018). Enhancing sensitivity of liquid chromatography-mass spectrometry of peptides and proteins using supercharging agents. International Journal of Mass Spectrometry, 427, 157-164.
Wang, J., & Zhang, S., & Xu, C., & Wojtas, L., & Akhmedov, N.G., & Chen, Hao, & Shi, X. (2018). Highly efficient and stereoselective thioallylation of alkynes: Possible gold redox catalysis with no need for a strong oxidant. Angewandte Chemie - International Edition, 57(23), 6915-6920.
Zheng, Q., & Tian, Y., & Ruan, X., & Chen, Hao, & Wu, X., & Xu, X., & Wang, G., & Hao, H., & Ye, H. (2018). Probing specific ligand-protein interactions by native-denatured exchange mass spectrometry. Analytica Chimica Acta, 1036, 58-65.
Chen, Z., & Jiang, Z., & Chen, N., & Shi, Q., & Tong, L., & Kong, F., & Cheng, X., & Chen, Hao, & Wang, C., & Tang, B. (2018). Target discovery of ebselen with a biotinylated probe. Chemical Communications, 54(68), 9506-9509.
Liu, P., & Zhao, P., & Graham Cooks, R., & Chen, Hao (2017). Atmospheric pressure neutral reionization mass spectrometry for structural analysis. Chemical Science, 8(9), 6499-6507.
Cai, Y., & Wang, J., & Zhang, Y., & Li, Z., & Hu, D., & Zheng, N., & Chen, Hao (2017). Detection of fleeting amine radical cations and elucidation of chain processes in visible-light-mediated [3 + 2] annulation by online mass spectrometric techniques. Journal of the American Chemical Society, 139(35), 12259-12266.
Cheng, S., & Wu, Q., & Xiao, H., & Chen, Hao (2017). Online monitoring of enzymatic reactions using time-resolved desorption electrospray ionization mass spectrometry. Analytical Chemistry, 89(4), 2338-2344.
Cheng, S., & Wu, Q., & Dewald, H.D., & Chen, Hao (2017). Online monitoring of methanol electro-oxidation reactions by ambient mass spectrometry. Journal of the American Society for Mass Spectrometry, 28(6), 1005-1012.
Wu, Q., & Cheng, S., & Chen, Hao, & Wang, C. (2017). ZIF-67 Templated synthesis of nanoporous carbon as an efficient adsorbent for preconcentration of flunitrazepam from beverage samples. Food Analytical Methods, 10(8), 2772-2780.
Cai, Y., & Liu, P., & Held, M.A., & Dewald, H.D., & Chen, Hao (2016). Coupling electrochemistry with probe electrospray ionization mass spectrometry. ChemPhysChem, 17(8), 1104-1108.
Zheng, Q., & Chen, Hao (2016). Development and applications of liquid sample desorption electrospray ionization mass spectrometry. Annual Review of Analytical Chemistry, 9, 411-448.
Wu, Q., & Cheng, S., & Li, Z., & Chen, Hao (2016). Highly sensitive mass spectrometric detection of flunitrazepam using magnetic graphene framework enrichment. Analytical Methods, 8(32), 6168-6175.
Li, Z., & Zhang, S., & Cai, Y., & Wu, Q., & Chen, Hao (2016). Hollow fiber-based solid-liquid phase microextraction combined with theta capillary electrospray ionization mass spectrometry for sensitive and accurate analysis of methamphetamine. Analytical Methods, 8(43), 7800-7807.
Peng, H., & Cai, R., & Xu, C., & Chen, Hao, & Shi, X. (2016). Nucleophile promoted gold redox catalysis with diazonium salts: C-Br, C-S and C-P bond formation through catalytic Sandmeyer coupling. Chemical Science, 7(9), 6190-6196.
Brown, T.A., & Hosseini-Nassab, N., & Chen, Hao, & Zare, R.N. (2016). Observation of electrochemically generated nitrenium ions by desorption electrospray ionization mass spectrometry. Chemical Science, 7(1), 329-332.
Ding, Z., & Jiang, M., & Chen, Hao, & Jin, Z., & Zhou, Mengchu (2016). Petri net based test case generation for evolved specification. Science China Information Sciences, 59(8),
Zheng, Q., & Zhang, H., & Wu, S., & Chen, Hao (2016). Probing protein 3D structures and conformational changes using electrochemistry-assisted isotope labeling cross-linking mass spectrometry. Journal of the American Society for Mass Spectrometry, 27(5), 864-875.
Ye, X., & Xu, C., & Wojtas, L., & Akhmedov, N.G., & Chen, Hao, & Shi, X. (2016). Silver-free palladium-catalyzed sp3 and sp2 C-H alkynylation promoted by a 1,2,3-triazole amine directing group. Organic Letters, 18(12), 2970-2973.
Li, L., & Wang, X., & Li, Q., & Liu, P., & Xu, K., & Chen, Hao, & Tang, B. (2015). An accurate mass spectrometric approach for the simultaneous comparison of GSH, Cys, and Hcy in L02 cells and HepG2 cells using new NPSP isotope probes. Chemical Communications, 51(56), 11317-11320.
Zheng, Q., & Liu, Y., & Chen, Q., & Hu, M., & Helmy, R., & Sherer, E.C., & Welch, C.J., & Chen, Hao (2015). Capture of reactive monophosphine-ligated palladium(0) intermediates by mass spectrometry. Journal of the American Chemical Society, 137(44), 14035-14038.
Brown, T.A., & Chen, Hao, & Zare, R.N. (2015). Detection of the short-lived radical cation intermediate in the electrooxidation of N,N-Dimethylaniline by mass spectrometry. Angewandte Chemie - International Edition, 54(38), 11183-11185.
Cheng, S., & Wang, J., & Cai, Y., & Loo, J.A., & Chen, Hao (2015). Enhancing performance of liquid sample desorption electrospray ionization mass spectrometry using trap and capillary columns. International Journal of Mass Spectrometry, 392, 73-79.
Kong, F., & Hu, B., & Gao, Y., & Xu, K., & Pan, X., & Huang, F., & Zheng, Q., & Chen, Hao, & Tang, B. (2015). Fluorescence imaging of selenol in HepG2 cell apoptosis induced by Na2SeO3. Chemical Communications, 51(15), 3102-3105.
Brown, T.A., & Chen, Hao, & Zare, R.N. (2015). Identification of fleeting electrochemical reaction intermediates using desorption electrospray ionization mass spectrometry. Journal of the American Chemical Society, 137(23), 7274-7277.
Cai, Y., & Zheng, Q., & Liu, Y., & Helmy, R., & Loo, J.A., & Chen, Hao (2015). Integration of electrochemistry with ultraperformance liquid chromatography/mass spectrometry. European Journal of Mass Spectrometry, 21(3), 341-351.
Cai, R., & Lu, M., & Aguilera, E.Y., & Xi, Y., & Akhmedov, N.G., & Petersen, J.L., & Chen, Hao, & Shi, X. (2015). Ligand-assisted gold-catalyzed cross-coupling with aryldiazonium salts: Redox gold catalysis without an external oxidant. Angewandte Chemie - International Edition, 54(30), 8772-8776.
Liu, P., & Cooks, R.G., & Chen, Hao (2015). Nuclear magnetic resonance structure elucidation of peptide b2 ions. Angewandte Chemie - International Edition, 54(5), 1547-1550.
Liu, P., & Zheng, Q., & Dewald, H.D., & Zhou, R., & Chen, Hao (2015). The study of electrochemistry with ambient mass spectrometry. TrAC - Trends in Analytical Chemistry, 70, 20-30.
Cai, Y., & Adams, D., & Chen, Hao (2014). A new splitting method for both analytical and preparative LC/MS. Journal of the American Society for Mass Spectrometry, 25(2), 286-292.
Cai, Y., & Liu, Y., & Helmy, R., & Chen, Hao (2014). Coupling of ultrafast LC with mass spectrometry by DESI. Journal of the American Society for Mass Spectrometry, 25(10), 1820-1823.
Zheng, Q., & Zhang, H., & Tong, L., & Wu, S., & Chen, Hao (2014). Cross-linking electrochemical mass spectrometry for probing protein three-dimensional structures. Analytical Chemistry, 86(18), 8983-8991.
Liu, P., & Forni, A., & Chen, Hao (2014). Development of solvent-free ambient mass spectrometry for green chemistry applications. Analytical Chemistry, 86(8), 4024-4032.
Su, Y., & Lu, M., & Dong, B., & Chen, Hao, & Shi, X. (2014). Silver-catalyzed alkyne activation: The surprising ligand effect. Advanced Synthesis and Catalysis, 356(4), 692-696.
Pan, N., & Liu, P., & Cui, W., & Tang, B., & Shi, J., & Chen, Hao (2013). Highly efficient ionization of phosphopeptides at low pH by desorption electrospray ionization mass spectrometry. Analyst, 138(5), 1321-1324.
Zheng, Q., & Zhang, H., & Chen, Hao (2013). Integration of online digestion and electrolytic reduction with mass spectrometry for rapid disulfide-containing protein structural analysis. International Journal of Mass Spectrometry, 353, 84-92.
Liu, P., & Zhang, J., & Ferguson, C.N., & Chen, Hao, & Loo, J.A. (2013). Measuring protein-ligand interactions using liquid sample desorption electrospray ionization mass spectrometry. Analytical Chemistry, 85(24), 11966-11972.
Lu, M., & Campbell, J.L., & Chauhan, R., & Grapperhaus, C.A., & Chen, Hao (2013). Probing the reactivity and radical nature of oxidized transition metal-thiolate complexes by mass spectrometry. Journal of the American Society for Mass Spectrometry, 24(4), 502-512.
Liu, P., & Lu, M., & Zheng, Q., & Zhang, Y., & Dewald, H.D., & Chen, Hao (2013). Recent advances of electrochemical mass spectrometry. Analyst, 138(19), 5519-5539.
Weldy, E., & Wolff, C., & Miao, Z., & Chen, Hao (2013). Selective and sensitive detection of chromium(VI) in waters using electrospray ionization mass spectrometry. Science and Justice, 53(3), 293-300.
Zhang, Y., & Cui, W., & Zhang, H., & Dewald, H.D., & Chen, Hao (2012). Electrochemistry-assisted top-down characterization of disulfide-containing proteins. Analytical Chemistry, 84(8), 3838-3842.
Wang, Z., & Zhang, Y., & Zhang, H., & Harrington, P.B., & Chen, Hao (2012). Fast and selective modification of thiol proteins/peptides by N-(phenylseleno) phthalimide. Journal of the American Society for Mass Spectrometry, 23(3), 520-529.
Lu, M., & Wolff, C., & Cui, W., & Chen, Hao (2012). Investigation of some biologically relevant redox reactions using electrochemical mass spectrometry interfaced by desorption electrospray ionization. Analytical and Bioanalytical Chemistry, 403(2), 355-365.
D'Aloise, P., & Chen, Hao (2012). Rapid determination of flunitrazepam in alcoholic beverages by desorption electrospray ionization-mass spectrometry. Science and Justice, 52(1), 2-8.
Liu, Y., & Miao, Z., & Lakshmanan, R., & Loo, R.R.O., & Loo, J.A., & Chen, Hao (2012). Signal and charge enhancement for protein analysis by liquid chromatography-mass spectrometry with desorption electrospray ionization. International Journal of Mass Spectrometry, 325-327, 161-166.
Chen, Z., & Li, Q., & Sun, Q., & Chen, Hao, & Wang, X., & Li, N., & Yin, M., & Xie, Y., & Li, H., & Tang, B. (2012). Simultaneous determination of reactive oxygen and nitrogen species in mitochondrial compartments of apoptotic HepG2 cells and PC12 cells based on microchip electrophoresis-laser-induced fluorescence. Analytical Chemistry, 84(11), 4687-4694.
Liu, P., & Lanekoff, I.T., & Laskin, J., & Dewald, H.D., & Chen, Hao (2012). Study of electrochemical reactions using nanospray desorption electrospray ionization mass spectrometry. Analytical Chemistry, 84(13), 5737-5743.
Zhang, Y., & Yuan, Z., & Dewald, H.D., & Chen, Hao (2011). Coupling of liquid chromatography with mass spectrometry by desorption electrospray ionization (DESI). Chemical Communications, 47(14), 4171-4173.
Sun, X., & Miao, Z., & Yuan, Z., & Harrington, P.D.B., & Colla, J., & Chen, Hao (2011). Coupling of single droplet micro-extraction with desorption electrospray ionization-mass spectrometry. International Journal of Mass Spectrometry, 301(1-3), 102-108.
Miao, Z., & Chen, Hao, & Liu, P., & Liu, Y. (2011). Development of submillisecond time-resolved mass spectrometry using desorption electrospray ionization. Analytical Chemistry, 83(11), 3994-3997.
Ferguson, C.N., & Benchaar, S.A., & Miao, Z., & Loo, J.A., & Chen, Hao (2011). Direct ionization of large proteins and protein complexes by desorption electrospray ionization-mass spectrometry. Analytical Chemistry, 83(17), 6468-6473.
Zhang, Y., & Dewald, H.D., & Chen, Hao (2011). Online mass spectrometric analysis of proteins/peptides following electrolytic cleavage of disulfide bonds. Journal of Proteome Research, 10(3), 1293-1304.
Zhang, Y., & Zhang, H., & Cui, W., & Chen, Hao (2011). Tandem MS analysis of selenamide-derivatized peptide ions. Journal of the American Society for Mass Spectrometry, 22(9), 1610-1621.
Zhang, Y., & Chen, Hao (2010). Detection of saccharides by reactive desorption electrospray ionization (DESI) using modified phenylboronic acids. International Journal of Mass Spectrometry, 289(2-3), 98-107.
Xu, K., & Zhang, Y., & Tang, B., & Laskin, J., & Roach, P.J., & Chen, Hao (2010). Study of highly selective and efficient thiol derivatization using selenium reagents by mass spectrometry. Analytical Chemistry, 82(16), 6926-6932.
Gau, B.C., & Chen, Hao, & Zhang, Y., & Gross, M.L. (2010). Sulfate radical anion as a new reagent for fast photochemical oxidation of proteins. Analytical Chemistry, 82(18), 7821-7827.
Miao, Z., & Wu, S., & Chen, Hao (2010). The study of protein conformation in solution via direct sampling by desorption electrospray ionization mass spectrometry. Journal of the American Society for Mass Spectrometry, 21(10), 1730-1736.
Miao, Z., & Chen, Hao (2009). Direct analysis of liquid samples by desorption electrospray ionization-mass spectrometry (DESI-MS). Journal of the American Society for Mass Spectrometry, 20(1), 10-19.
Li, J., & Dewald, H.D., & Chen, Hao (2009). Online coupling of electrochemical reactions with liquid sample desorption electrospray ionization-mass spectrometry. Analytical Chemistry, 81(23), 9716-9722.
Lu, W., & László, C.F., & Miao, Z., & Chen, Hao, & Wu, S. (2009). The role of nitric-oxide synthase in the regulation of UVB light-induced phosphorylation of the α subunit of eukaryotic initiation factor 2. Journal of Biological Chemistry, 284(36), 24281-24288.
Eberlin, L.S., & Xia, Y., & Chen, Hao, & Cooks, R.G. (2008). Atmospheric pressure thermal dissociation of phospho- and sulfopeptides. Journal of the American Society for Mass Spectrometry, 19(12), 1897-1905.
Cotte-Rodríguez, I., & Hernández-Soto, H., & Chen, Hao, & Cooks, R.G. (2008). In situ trace detection of peroxide explosives by desorption electrospray ionization and desorption atmospheric pressure chemical ionization. Analytical Chemistry, 80(5), 1512-1519.
Chen, Hao, & Eberlin, L.S., & Nefliu, M., & Augusti, R., & Cooks, R.G. (2008). Organic reactions of ionic intermediates promoted by atmospheric-pressure thermal activation. Angewandte Chemie - International Edition, 47(18), 3422-3425.
Peng, W.-P., & Goodwin, M.P., & Chen, Hao, & Cooks, R.G., & Wilker, J. (2008). Thermal formation of mixed-metal inorganic complexes at atmospheric pressure. Rapid Communications in Mass Spectrometry, 22(22), 3540-3548.
Chen, Hao, & Zuo, Yuegang (2007). Identification of flavonol glycosides in American cranberry fruit. Food Chemistry, 101, 1357-1364.
Chen, Hao, & Eberlin, L.S., & Cooks, R.G. (2007). Neutral fragment mass spectra via ambient thermal dissociation of peptide and protein ions. Journal of the American Chemical Society, 129(18), 5880-5886.
Huang, G., & Chen, Hao, & Zhang, X., & Cooks, R.G., & Ouyang, Z. (2007). Rapid screening of anabolic steroids in urine by reactive desorption electrospray ionization. Analytical Chemistry, 79(21), 8327-8332.
Augusti, R., & Chen, Hao, & Eberlin, L.S., & Nefliu, M., & Cooks, R.G. (2006). Atmospheric pressure Eberlin transacetalization reactions in the heterogeneous liquid/gas phase. International Journal of Mass Spectrometry, 253(3), 281-287.
Chen, Hao, & Cotte-Rodríguez, I., & Cooks, R.G. (2006). cis-Diol functional group recognition by reactive desorption electrospray ionization (DESI). Chemical Communications, 6(6), 597-599.
Goebbert, Daniel J, & Chen, Hao, & Wenthold, Paul G (2006). Collision‐induced dissociation studies of protonated ether—(H2O)n (n = 1–3) clusters. Journal of Mass Spectrometry, 41, 242-247.
Deng, Yiwei, & Zhang, Kai, & Chen, Hao, & Wu, Taixing, & Krzyaniak, Metthew, & Wellons, Amina, & Bolla, Dawn, & Douglas, Kenneth, & Zuo, Yuegang (2006). Iron-catalyzed photochemical transformation of benzoic acid in atmospheric liquids: Product identification and reaction mechanisms. Atmospheric Environment, 40, 3665-3676.
Cooks, R.G., & Chen, Hao, & Eberlin, M.N., & Zheng, X., & Tao, W.A. (2006). Polar acetalization and transacetalization in the gas phase: The Eberlin reaction. Chemical Reviews, 106(1), 188-211.
Cotte-Rodríguez, I., & Chen, Hao, & Cooks, R.G. (2006). Rapid trace detection of triacetone triperoxide (TATP) by complexation reactions during desorption electrospray ionization. Chemical Communications(9), 953-955.
Chen, Hao, & Ouyang, Z., & Cooks, R.G. (2006). Thermal production and reactions of organic ions at atmospheric pressure. Angewandte Chemie - International Edition, 45(22), 3656-3660.
Popov, I.A., & Chen, Hao, & Kharybin, O.N., & Nikolaev, E.N., & Cooks, R.G. (2005). Detection of explosives on solid surfaces by thermal desorption and ambient ion/molecule reactions. Chemical Communications(15), 1953-1955.
Chen, Hao, & Cooks, R.G., & Meurer, E.C., & Eberlin, M.N. (2005). Hydrogen/chlorine exchange reactions of gaseous carbanions. Journal of the American Society for Mass Spectrometry, 16(12), 2045-2051.
Chen, Hao, & Xu, R., & Chen, Hao, & Cooks, R.G., & Ouyang, Z. (2005). Ion/molecule reactions in a miniature RIT mass spectrometer. Journal of Mass Spectrometry, 40(11), 1403-1411.
Chen, Hao, & Justes, D.R., & Cooks, R.G. (2005). Proton affinities of N-heterocyclic carbene super bases. Organic Letters, 7(18), 3949-3952.
Song, Y., & Chen, Hao, & Cooks, R.G. (2005). Reactivity of acetonyl anion with nitroaromatics: An atmospheric pressure chemical ionization study. Rapid Communications in Mass Spectrometry, 19(23), 3493-3499.
Bagheri, H., & Chen, Hao, & Cooks, R.G. (2004). Chiral recognition by proton transfer reactions with optically active amines and alcohols. Chemical Communications(23), 2740-2741.
Augusti, R., & Turowski, M., & Chen, Hao, & Cooks, R.G. (2004). Dissociation of ionized benzophenones investigated by the kinetic method: Effective temperature, steric effects and gas-phase CO+. affinities of phenyl radicals. Journal of Mass Spectrometry, 39(5), 558-564.
Augusti, R., & Augusti, D.V., & Chen, Hao, & Cooks, R.G. (2004). Gas-phase halide affinity of aliphatic alcohols estimated by the kinetic method. European Journal of Mass Spectrometry, 10(6), 847-855.
Meurer, E.C., & Chen, Hao, & Riter, L., & Cotte-Rodriguez, I., & Eberlin, M.N., & Cooks, R.G. (2004). Gas-phase reactions for selective detection of the explosives TNT and RDX. Chemical Communications, 4(1), 40-41.
Chen, Hao, & Chen, Hao, & Cooks, R.G., & Bagheri, H. (2004). Generation of arylnitrenium ions by nitro-reduction and gas-phase synthesis of N-heterocycles. Journal of the American Society for Mass Spectrometry, 15(11), 1675-1688.
Meurer, E.C., & Chen, Hao, & Riter, L.S., & Cooks, R.G., & Eberlin, M.N. (2004). Meerwein reaction of phosphonium ions with epoxides and thioepoxides in the gas phase. Journal of the American Society for Mass Spectrometry, 15(3), 398-405.
Chen, Hao, & Chen, Hao, & Cooks, R.G. (2004). Meisenheimer complexes bonded at carbon and at oxygen. Journal of the American Society for Mass Spectrometry, 15(7), 998-1004.
Chen, Hao, & Zheng, X., & Yang, P., & Cooks, R.G. (2004). Reduction of nitroaromatics to arylnitrenium ions by vinyl halide cations. Chemical Communications, 10(6), 688-689.
Riter, Leah S, & Meurer, Eduardo C, & Handberg, Eric S, & Laughlin, Brian C, & Chen, Hao, & Patterson, Garth E, & Cooks, R Graham (2003). Ion/molecule reactions performed in a miniature cylindrical ion trap mass spectrometer. Analyst, 28, 1112-1118.
Chen, Hao, & Zheng, X., & Cooks, R.G. (2003). Ketalization of phosphonium ions by 1,4-dioxane: Selective detection of the chemical warfare agent simulant DMMP in mixtures using ion/molecule reactions. Journal of the American Society for Mass Spectrometry, 14(3), 182-188.
Zuo, Yuegang, & Chen, Hao (2003). Simultaneous determination of sulfite, sulfate, and hydroxymethanesulfonate in atmospheric waters by ion-pair HPLC technique. Talenta, 59, 875-881.
Zuo, Yuegang, & Chen, Hao, & Deng, Yiwei (2002). Simultaneous determination of catechins, caffeine and gallic acids in green, Oolong, black and pu-erh teas using HPLC with a photodiode array detector. Talenta, 57, 307-316.
Yang, Yonggang, & Chen, Hao, & Tang, Geng, & Wen, Jianxun (2002). Synthesis and mesomorphic properties of several series of fluorinated ester liquid crystals. Liquid Crystals, 29, 255-261.
Yang, Yonggang, & Chen, Hao, & Tang, Geng, & Wen, Jianxun (2002). Synthesis and mesomorphic properties of some fluorinated benzoate liquid crystals. Molecular Crystals and Liquid Crystals, 373, 1-15.
Chen, Hao, & Zuo, Yuegang, & Deng, Yiwei (2001). Separation and determination of flavonoids and other phenolic compounds in cranberry juice by high-performance liquid chromatography. Journal of Chromatography A, 913, 387-395.
Wen, Jianxun, & Chen, Hao, & Shen, Yuehai (1999). The first series of ferroelectric steroidal fluorinated liquid crystals. Liquid Crystals, 26, 1833-1834.
COLLAPSE
Book Review
Technical and Methodological Advances in Proteomics
Frontiers in Chemistry, 2021
Review of "Mass spectrometry instrumentation, interpretation, and applications"
Journal of the American Society for Mass Spectrometry, 2010
Frontiers in Chemistry, 2021
Review of "Mass spectrometry instrumentation, interpretation, and applications"
Journal of the American Society for Mass Spectrometry, 2010
Conference Proceeding
Resource-oriented petri net-based approach to deadlock prevention of AMSs
Proceedings - 2015 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2015, 2016
Proceedings - 2015 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2015, 2016
Book
Cotte-Rodriguez, I., & Miao, Z., & Zhang, Y., & Chen, Hao (2013). Introduction to protein mass spectrometry. Characterization of Protein Therapeutics using Mass Spectrometry
Cotte-Rodriguez, I., & Zhang, Y., & Miao, Z., & Chen, Hao (2011). Ionization methods in protein mass spectrometry. Protein and Peptide Mass Spectrometry in Drug Discovery
Chen, Hao, & Li, J. (2011). Rapid analysis of drug-related substances using desorption electrospray ionization and direct analysis in real time ionization mass spectrometry. Characterization of Impurities and Degradants Using Mass Spectrometry
Chen, Hao (2010). Historical perspectives in the study of ion chemistry by mass spectrometry: From the gas phase to solution. Reactive Intermediates: MS Investigations in Solution
Cotte-Rodriguez, I., & Zhang, Y., & Miao, Z., & Chen, Hao (2011). Ionization methods in protein mass spectrometry. Protein and Peptide Mass Spectrometry in Drug Discovery
Chen, Hao, & Li, J. (2011). Rapid analysis of drug-related substances using desorption electrospray ionization and direct analysis in real time ionization mass spectrometry. Characterization of Impurities and Degradants Using Mass Spectrometry
Chen, Hao (2010). Historical perspectives in the study of ion chemistry by mass spectrometry: From the gas phase to solution. Reactive Intermediates: MS Investigations in Solution