Cristiano Dias
Education
Ph.D.; McGill University, Canada; ; 2007
M.S.; Universite de Montreal, Canada; ; 2001
B.S.; Universidade de Brasilia, Brazil; ; 1998
M.S.; Universite de Montreal, Canada; ; 2001
B.S.; Universidade de Brasilia, Brazil; ; 1998
2024 Fall Courses
PHYS 700B - MASTER'S PROJECT
PHYS 726 - INDEPENDENT STUDY II
PHYS 790A - DOCT DISSERTATION & RES
PHYS 490 - INDEPENDENT STUDY
PHYS 701B - MASTER'S THESIS
PHYS 491 - INDEPENDENT STUDY II
PHYS 792 - PRE-DOCTORAL RESEARCH
PHYS 701C - MASTER'S THESIS
PHYS 725 - INDEPENDENT STUDY I
PHYS 726 - INDEPENDENT STUDY II
PHYS 790A - DOCT DISSERTATION & RES
PHYS 490 - INDEPENDENT STUDY
PHYS 701B - MASTER'S THESIS
PHYS 491 - INDEPENDENT STUDY II
PHYS 792 - PRE-DOCTORAL RESEARCH
PHYS 701C - MASTER'S THESIS
PHYS 725 - INDEPENDENT STUDY I
Teaching Interests
1) Freshman Physics Courses (e.g., Phys. 111)
2) Biophysics courses (e.g., BioPhysics 350).
3) Graduate level "Statistical Mechanics".
2) Biophysics courses (e.g., BioPhysics 350).
3) Graduate level "Statistical Mechanics".
Past Courses
PHYS 111: PHYSICS I
PHYS 204: BIOPHYSICS OF LIFE
PHYS 350: BIOPHYSICS
PHYS 451: BIOPHYSICS II
PHYS 204: BIOPHYSICS OF LIFE
PHYS 350: BIOPHYSICS
PHYS 451: BIOPHYSICS II
Research Interests
In our lab, we study non-equilibrium phenomena using atomistic and statistical mechanics models to understand biological systems. Our recent focus has been in protein self-assembly in solution and on the surface of lipid membranes. A better understanding of self-assembly and how it leads to the formation of supramolecular structures is allowing us to design better biomaterials. Our study on membrane damage is improving our understanding of amyloid toxicity in diseases like Alzheimer's and Parkinson's. These studies are being carried out in collaboration with experimentalist and theoreticians. These interdisciplinary topics lie at the interface of physics, chemistry, biology, and material science.
Journal Article
Dias, Cristiano Luis (2024). Growth kinetics of amyloid-like fibrils: An integrated atomistic simulation and continuum theory approach. PNAS Nexus, 3, 1-12.
Dias, Cristiano Luis (2024). Peptide Self-Assembly into Amyloid Fibrils: Unbiased All-Atom Simulations. J. Phys. Chem. B,
Dias, Cristiano Luis (2023). Nucleation and Growth of Amyloid Fibrils. J. Phys. Chem. B, 127, 9759-9770.
Dias, Cristiano Luis (2023). Peptide−Membrane Binding: Effects of the Amino Acid Sequence. J. Phys. Chem. B, 127, 912-920.
Yang, Yanxing , & Distaffen, Hannah , & Jalali, Sharareh , & Nieuwkoop, Andrew J., & Nilsson, Bradley, & Dias, Cristiano Luis (2022). Atomic Insights into Amyloid-Induced Membrane Damage. ACS Chem. Neurosci., 13, 2766–2777.
Dias, Cristiano Luis (2024). Peptide Self-Assembly into Amyloid Fibrils: Unbiased All-Atom Simulations. J. Phys. Chem. B,
Dias, Cristiano Luis (2023). Nucleation and Growth of Amyloid Fibrils. J. Phys. Chem. B, 127, 9759-9770.
Dias, Cristiano Luis (2023). Peptide−Membrane Binding: Effects of the Amino Acid Sequence. J. Phys. Chem. B, 127, 912-920.
Yang, Yanxing , & Distaffen, Hannah , & Jalali, Sharareh , & Nieuwkoop, Andrew J., & Nilsson, Bradley, & Dias, Cristiano Luis (2022). Atomic Insights into Amyloid-Induced Membrane Damage. ACS Chem. Neurosci., 13, 2766–2777.
SHOW MORE
Jalali, Sharareh, & Yang, Yanxing, & Mahmoudinobar, Farbod, & Nilsson, Bradley, & Dias, Cristiano Luis (2022). Using all-atom simulations in explicit solvent to study aggregation of amphipathic peptides into amyloid-like fibrils. Journal of Molecular Liquids , 347, 118283.
Yang, Yanxing, & Jalali, Sharareh, & Nilsson, Bradley, & Dias, Cristiano Luis (2021). Binding Mechanisms of Amyloid-like Peptides to Lipid Bilayers and Effects of Divalent Cations. ACS Chem. Neurosci. , 12, 2027−2035.
Dias, Cristiano Luis (2021). Effects of Ions and Small Compounds on the Structure of Aβ42 Monomers. J. Phys. Chem. B, 125, 1085-1097.
Dias, Cristiano Luis (2021). Methane Clathrate Formation is Catalyzed and Kinetically Inhibited by the Same Molecule: Two Facets of Methanol. J. Phys. Chem. B, 125, 4162-4168.
Dias, Cristiano Luis (2020). Role of Cholesterol on Binding of Amyloid Fibrils to Lipid Bilayers. J. Phys. Chem. B, 124, 3036-3042.
Dias, Cristiano Luis (2019). GRADE: A code to determine clathrate hydrate structures. Computer Physics Communications, 244, 385-391.
Dias, Cristiano Luis (2019). Individual and combined effects of urea and trimethylamine N-oxide (TMAO) on protein structures. Journal of Molecular Liquids, 293, 111443.
Jeong, Young, & Dias, Cristiano Luis, & Diekman, Casey O., & Brochon, Helen, & Kim, Pyonghwa, & Kaur, Manpreet, & Kim, Yong-Sung, & Jang, Hye-In, & Kim, Yong I. (2019). Magnesium regulates the circadian oscillator in cyanobacteria. Journal of Biological Rhythms, 34(4), 380-390.
Jeong, Young Mi, & Dias, Cristiano Luis, & Diekman, Casey O., & Brochon, Helene, & Kim, Pyonghwa, & Kaur, Manpreet, & Kim, Yong-Sung, & Jang, Hye-In, & Kim, Yong I. (2019). Magnesium regulates the circadian oscillator in cyanobacteria. . Journal of Biological Rhythms, 34(4), 380-390.
Dias, Cristiano Luis, & Jampani, Srinivasa Rao, & Mahmoudinobar, Farbod , & Su, Zhaoqian (2015). Thermodynamics of Aβ16–21 dissociation from a fibril: Enthalpy, entropy, and volumetric properties. Proteins: Structure, Function, and Bioinformatics, 83, 1963–1972.
Dias, Cristiano Luis, & Su, Zhaoqian (2014). Driving beta-strands into fibrils. J. Phys. Chem. B, 118, 10830.
Dias, Cristiano Luis, & Chan, Hue Sun (2014). Pressure-Dependence Properties of Elementary Hydrophobic Interactions: Ramifications for Activation Properties of Protein Folding. J. Phys. Chem. B, 118 , 7488 (2014) , 7488.
Dias, Cristiano Luis, & Narayanan, Chitra (2014). Exploring the free energy landscape of a model beta-hairpin peptide and its isoform.. PROTEIN: Structure, Function, and Bioinformatics, 82, 2394.
Dias, Cristiano Luis, & Urbic, Tomaz (2014). Hydration of non-polar anti-parallel beta-sheets. J. Chem. Phys., 140, 165101 .
Dias, Cristiano Luis, & Urbic, Tomaz (2014). Properties of Lennard-Jones dimeric fluid in two dimensions: An integral equation study. The Journal of Chemical Physics, 140, 094703.
Dias, Cristiano Luis, & Narayanan, Chitra (2013). Hydrophobic interactions and hydrogen bonds in beta-sheet formation. Journal of Chemical Physics, 139, 115103.
Yang, Yanxing, & Jalali, Sharareh, & Nilsson, Bradley, & Dias, Cristiano Luis (2021). Binding Mechanisms of Amyloid-like Peptides to Lipid Bilayers and Effects of Divalent Cations. ACS Chem. Neurosci. , 12, 2027−2035.
Dias, Cristiano Luis (2021). Effects of Ions and Small Compounds on the Structure of Aβ42 Monomers. J. Phys. Chem. B, 125, 1085-1097.
Dias, Cristiano Luis (2021). Methane Clathrate Formation is Catalyzed and Kinetically Inhibited by the Same Molecule: Two Facets of Methanol. J. Phys. Chem. B, 125, 4162-4168.
Dias, Cristiano Luis (2020). Role of Cholesterol on Binding of Amyloid Fibrils to Lipid Bilayers. J. Phys. Chem. B, 124, 3036-3042.
Dias, Cristiano Luis (2019). GRADE: A code to determine clathrate hydrate structures. Computer Physics Communications, 244, 385-391.
Dias, Cristiano Luis (2019). Individual and combined effects of urea and trimethylamine N-oxide (TMAO) on protein structures. Journal of Molecular Liquids, 293, 111443.
Jeong, Young, & Dias, Cristiano Luis, & Diekman, Casey O., & Brochon, Helen, & Kim, Pyonghwa, & Kaur, Manpreet, & Kim, Yong-Sung, & Jang, Hye-In, & Kim, Yong I. (2019). Magnesium regulates the circadian oscillator in cyanobacteria. Journal of Biological Rhythms, 34(4), 380-390.
Jeong, Young Mi, & Dias, Cristiano Luis, & Diekman, Casey O., & Brochon, Helene, & Kim, Pyonghwa, & Kaur, Manpreet, & Kim, Yong-Sung, & Jang, Hye-In, & Kim, Yong I. (2019). Magnesium regulates the circadian oscillator in cyanobacteria. . Journal of Biological Rhythms, 34(4), 380-390.
Dias, Cristiano Luis, & Jampani, Srinivasa Rao, & Mahmoudinobar, Farbod , & Su, Zhaoqian (2015). Thermodynamics of Aβ16–21 dissociation from a fibril: Enthalpy, entropy, and volumetric properties. Proteins: Structure, Function, and Bioinformatics, 83, 1963–1972.
Dias, Cristiano Luis, & Su, Zhaoqian (2014). Driving beta-strands into fibrils. J. Phys. Chem. B, 118, 10830.
Dias, Cristiano Luis, & Chan, Hue Sun (2014). Pressure-Dependence Properties of Elementary Hydrophobic Interactions: Ramifications for Activation Properties of Protein Folding. J. Phys. Chem. B, 118 , 7488 (2014) , 7488.
Dias, Cristiano Luis, & Narayanan, Chitra (2014). Exploring the free energy landscape of a model beta-hairpin peptide and its isoform.. PROTEIN: Structure, Function, and Bioinformatics, 82, 2394.
Dias, Cristiano Luis, & Urbic, Tomaz (2014). Hydration of non-polar anti-parallel beta-sheets. J. Chem. Phys., 140, 165101 .
Dias, Cristiano Luis, & Urbic, Tomaz (2014). Properties of Lennard-Jones dimeric fluid in two dimensions: An integral equation study. The Journal of Chemical Physics, 140, 094703.
Dias, Cristiano Luis, & Narayanan, Chitra (2013). Hydrophobic interactions and hydrogen bonds in beta-sheet formation. Journal of Chemical Physics, 139, 115103.
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