Cristiano Dias
Education
Ph.D.; McGill University, Canada; ; 2007
M.S.; Universite de Montreal, Canada; ; 2001
B.S.; Universidade de Brasilia, Brazil; ; 1998
M.S.; Universite de Montreal, Canada; ; 2001
B.S.; Universidade de Brasilia, Brazil; ; 1998
2025 Spring Courses
PHYS 700B - MASTER'S PROJECT
PHYS 726 - INDEPENDENT STUDY II
PHYS 790A - DOCT DISSERTATION & RES
PHYS 111 - PHYSICS I
MTSE 792B - PRE-DOCTORAL RESEARCH
PHYS 490 - INDEPENDENT STUDY
PHYS 701B - MASTER'S THESIS
PHYS 491 - INDEPENDENT STUDY II
PHYS 792 - PRE-DOCTORAL RESEARCH
PHYS 701C - MASTER'S THESIS
PHYS 725 - INDEPENDENT STUDY I
PHYS 726 - INDEPENDENT STUDY II
PHYS 790A - DOCT DISSERTATION & RES
PHYS 111 - PHYSICS I
MTSE 792B - PRE-DOCTORAL RESEARCH
PHYS 490 - INDEPENDENT STUDY
PHYS 701B - MASTER'S THESIS
PHYS 491 - INDEPENDENT STUDY II
PHYS 792 - PRE-DOCTORAL RESEARCH
PHYS 701C - MASTER'S THESIS
PHYS 725 - INDEPENDENT STUDY I
Teaching Interests
1) Freshman Physics Courses (e.g., Phys. 111)
2) Biophysics courses (e.g., BioPhysics 350).
3) Graduate level "Statistical Mechanics".
2) Biophysics courses (e.g., BioPhysics 350).
3) Graduate level "Statistical Mechanics".
Past Courses
PHYS 111: PHYSICS I
PHYS 204: BIOPHYSICS OF LIFE
PHYS 350: BIOPHYSICS
PHYS 451: BIOPHYSICS II
PHYS 204: BIOPHYSICS OF LIFE
PHYS 350: BIOPHYSICS
PHYS 451: BIOPHYSICS II
Research Interests
In our lab, we study non-equilibrium phenomena using atomistic and statistical mechanics models to understand biological systems. Our recent focus has been in protein self-assembly in solution and on the surface of lipid membranes. A better understanding of self-assembly and how it leads to the formation of supramolecular structures is allowing us to design better biomaterials. Our study on membrane damage is improving our understanding of amyloid toxicity in diseases like Alzheimer's and Parkinson's. These studies are being carried out in collaboration with experimentalist and theoreticians. These interdisciplinary topics lie at the interface of physics, chemistry, biology, and material science.
Journal Article
Cristiano Luis Dias. 2024. “Growth kinetics of amyloid-like fibrils: An integrated atomistic simulation and continuum theory approach.” PNAS Nexus, vol. 3, pp. 1-12.
Cristiano Luis Dias. 2024. “Peptide Self-Assembly into Amyloid Fibrils: Unbiased All-Atom Simulations.” J. Phys. Chem. B.
Cristiano Luis Dias. 2023. “Nucleation and Growth of Amyloid Fibrils.” J. Phys. Chem. B, vol. 127, pp. 9759-9770.
Cristiano Luis Dias. 2023. “Peptide−Membrane Binding: Effects of the Amino Acid Sequence.” J. Phys. Chem. B, vol. 127, pp. 912-920.
Yanxing Yang, Hannah Distaffen, Sharareh Jalali, Andrew J. Nieuwkoop, Bradley Nilsson, Cristiano Luis Dias. 2022. “Atomic Insights into Amyloid-Induced Membrane Damage.” ACS Chem. Neurosci., vol. 13, pp. 2766–2777.
Cristiano Luis Dias. 2024. “Peptide Self-Assembly into Amyloid Fibrils: Unbiased All-Atom Simulations.” J. Phys. Chem. B.
Cristiano Luis Dias. 2023. “Nucleation and Growth of Amyloid Fibrils.” J. Phys. Chem. B, vol. 127, pp. 9759-9770.
Cristiano Luis Dias. 2023. “Peptide−Membrane Binding: Effects of the Amino Acid Sequence.” J. Phys. Chem. B, vol. 127, pp. 912-920.
Yanxing Yang, Hannah Distaffen, Sharareh Jalali, Andrew J. Nieuwkoop, Bradley Nilsson, Cristiano Luis Dias. 2022. “Atomic Insights into Amyloid-Induced Membrane Damage.” ACS Chem. Neurosci., vol. 13, pp. 2766–2777.
SHOW MORE
Sharareh Jalali, Yanxing Yang, Farbod Mahmoudinobar, Bradley Nilsson, Cristiano Luis Dias. 2022. “Using all-atom simulations in explicit solvent to study aggregation of amphipathic peptides into amyloid-like fibrils.” Journal of Molecular Liquids , vol. 347, pp. 118283.
Yanxing Yang, Sharareh Jalali, Bradley Nilsson, Cristiano Luis Dias. 2021. “Binding Mechanisms of Amyloid-like Peptides to Lipid Bilayers and Effects of Divalent Cations.” ACS Chem. Neurosci. , vol. 12, pp. 2027−2035.
Cristiano Luis Dias. 2021. “Effects of Ions and Small Compounds on the Structure of Aβ42 Monomers.” J. Phys. Chem. B, vol. 125, pp. 1085-1097.
Cristiano Luis Dias. 2021. “Methane Clathrate Formation is Catalyzed and Kinetically Inhibited by the Same Molecule: Two Facets of Methanol.” J. Phys. Chem. B, vol. 125, pp. 4162-4168.
Cristiano Luis Dias. 2020. “Role of Cholesterol on Binding of Amyloid Fibrils to Lipid Bilayers.” J. Phys. Chem. B, vol. 124, pp. 3036-3042.
Cristiano Luis Dias. 2019. “GRADE: A code to determine clathrate hydrate structures.” Computer Physics Communications, vol. 244, pp. 385-391.
Cristiano Luis Dias. 2019. “Individual and combined effects of urea and trimethylamine N-oxide (TMAO) on protein structures.” Journal of Molecular Liquids, vol. 293, pp. 111443.
Young Jeong, Cristiano Luis Dias, Casey O. Diekman, Helen Brochon, Pyonghwa Kim, Manpreet Kaur, Yong-Sung Kim, Hye-In Jang, Yong I. Kim. 2019. “Magnesium regulates the circadian oscillator in cyanobacteria.” Journal of Biological Rhythms, vol. 34, no. 4, pp. 380-390.
Young Mi Jeong, Cristiano Luis Dias, Casey O. Diekman, Helene Brochon, Pyonghwa Kim, Manpreet Kaur, Yong-Sung Kim, Hye-In Jang, Yong I. Kim. 2019. “Magnesium regulates the circadian oscillator in cyanobacteria. .” Journal of Biological Rhythms, vol. 34, no. 4, pp. 380-390.
Cristiano Luis Dias, Srinivasa Rao Jampani, Farbod Mahmoudinobar, Zhaoqian Su. 2015. “Thermodynamics of Aβ16–21 dissociation from a fibril: Enthalpy, entropy, and volumetric properties.” Proteins: Structure, Function, and Bioinformatics, vol. 83, pp. 1963–1972.
Cristiano Luis Dias, Zhaoqian Su. 2014. “Driving beta-strands into fibrils.” J. Phys. Chem. B, vol. 118, pp. 10830.
Cristiano Luis Dias, Hue Sun Chan. 2014. “Pressure-Dependence Properties of Elementary Hydrophobic Interactions: Ramifications for Activation Properties of Protein Folding.” J. Phys. Chem. B, vol. 118 , 7488 (2014) , pp. 7488.
Cristiano Luis Dias, Chitra Narayanan. 2014. “Exploring the free energy landscape of a model beta-hairpin peptide and its isoform..” PROTEIN: Structure, Function, and Bioinformatics, vol. 82, pp. 2394.
Cristiano Luis Dias, Tomaz Urbic. 2014. “Hydration of non-polar anti-parallel beta-sheets.” J. Chem. Phys., vol. 140, pp. 165101 .
Cristiano Luis Dias, Tomaz Urbic. 2014. “Properties of Lennard-Jones dimeric fluid in two dimensions: An integral equation study.” The Journal of Chemical Physics, vol. 140, pp. 094703.
Cristiano Luis Dias, Chitra Narayanan. 2013. “Hydrophobic interactions and hydrogen bonds in beta-sheet formation.” Journal of Chemical Physics, vol. 139, pp. 115103.
Yanxing Yang, Sharareh Jalali, Bradley Nilsson, Cristiano Luis Dias. 2021. “Binding Mechanisms of Amyloid-like Peptides to Lipid Bilayers and Effects of Divalent Cations.” ACS Chem. Neurosci. , vol. 12, pp. 2027−2035.
Cristiano Luis Dias. 2021. “Effects of Ions and Small Compounds on the Structure of Aβ42 Monomers.” J. Phys. Chem. B, vol. 125, pp. 1085-1097.
Cristiano Luis Dias. 2021. “Methane Clathrate Formation is Catalyzed and Kinetically Inhibited by the Same Molecule: Two Facets of Methanol.” J. Phys. Chem. B, vol. 125, pp. 4162-4168.
Cristiano Luis Dias. 2020. “Role of Cholesterol on Binding of Amyloid Fibrils to Lipid Bilayers.” J. Phys. Chem. B, vol. 124, pp. 3036-3042.
Cristiano Luis Dias. 2019. “GRADE: A code to determine clathrate hydrate structures.” Computer Physics Communications, vol. 244, pp. 385-391.
Cristiano Luis Dias. 2019. “Individual and combined effects of urea and trimethylamine N-oxide (TMAO) on protein structures.” Journal of Molecular Liquids, vol. 293, pp. 111443.
Young Jeong, Cristiano Luis Dias, Casey O. Diekman, Helen Brochon, Pyonghwa Kim, Manpreet Kaur, Yong-Sung Kim, Hye-In Jang, Yong I. Kim. 2019. “Magnesium regulates the circadian oscillator in cyanobacteria.” Journal of Biological Rhythms, vol. 34, no. 4, pp. 380-390.
Young Mi Jeong, Cristiano Luis Dias, Casey O. Diekman, Helene Brochon, Pyonghwa Kim, Manpreet Kaur, Yong-Sung Kim, Hye-In Jang, Yong I. Kim. 2019. “Magnesium regulates the circadian oscillator in cyanobacteria. .” Journal of Biological Rhythms, vol. 34, no. 4, pp. 380-390.
Cristiano Luis Dias, Srinivasa Rao Jampani, Farbod Mahmoudinobar, Zhaoqian Su. 2015. “Thermodynamics of Aβ16–21 dissociation from a fibril: Enthalpy, entropy, and volumetric properties.” Proteins: Structure, Function, and Bioinformatics, vol. 83, pp. 1963–1972.
Cristiano Luis Dias, Zhaoqian Su. 2014. “Driving beta-strands into fibrils.” J. Phys. Chem. B, vol. 118, pp. 10830.
Cristiano Luis Dias, Hue Sun Chan. 2014. “Pressure-Dependence Properties of Elementary Hydrophobic Interactions: Ramifications for Activation Properties of Protein Folding.” J. Phys. Chem. B, vol. 118 , 7488 (2014) , pp. 7488.
Cristiano Luis Dias, Chitra Narayanan. 2014. “Exploring the free energy landscape of a model beta-hairpin peptide and its isoform..” PROTEIN: Structure, Function, and Bioinformatics, vol. 82, pp. 2394.
Cristiano Luis Dias, Tomaz Urbic. 2014. “Hydration of non-polar anti-parallel beta-sheets.” J. Chem. Phys., vol. 140, pp. 165101 .
Cristiano Luis Dias, Tomaz Urbic. 2014. “Properties of Lennard-Jones dimeric fluid in two dimensions: An integral equation study.” The Journal of Chemical Physics, vol. 140, pp. 094703.
Cristiano Luis Dias, Chitra Narayanan. 2013. “Hydrophobic interactions and hydrogen bonds in beta-sheet formation.” Journal of Chemical Physics, vol. 139, pp. 115103.
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