Rajesh Dave
Rajesh Dave
Distinguished Professor, Chemical & Materials Engineering
308 York Center (YORK)
About Me
Prof. Dave, a Distinguished Professor in the CBPE Department, received the B. Tech. (1978) from Indian Institute of Technology, Bombay, and M.S. (1981) and Ph.D. (1983) from Utah State University, all in Mechanical Engineering.
Education
Ph.D.; Utah State University; Mechanical Engineering; 1983
M.S.; Utah State University; Mechanical Engineering; 1981
B.S.; Indian Institute of Technology; Mechanical Engineering; 1978
M.S.; Utah State University; Mechanical Engineering; 1981
B.S.; Indian Institute of Technology; Mechanical Engineering; 1978
Awards & Honors
2022 AIChE PD2M Award for Outstanding Contribution to QbD for Drug Product, AIChE
2021 Fellow of National Academy of Inventors (NAI), National Academy of Inventors
2021 Fellow of National Academy of Inventors (NAI), National Academy of Inventors
Website
2025 Spring Courses
CHE 701B - MASTERS THESIS
CHE 792 - PRE-DOCTORAL RESEARCH
PHEN 725 - INDEPENDENT STUDY
CHE 492 - RESEARCH & INDEP STUDY
PHEN 701B - MASTER'S THESIS
CHE 491 - RESEARCH & INDEP STUDY
CHE 700B - MASTERS PROJECT
MTEN 491 - RESEARCH & INDEPENDENT STUDY I
MTEN 726 - INDEPENDENT STUDY II
MTEN 792 - PRE-DOCTORAL RESEARCH
CHE 706 - INDEPENDENT STUDY II
CHE 790A - DOCT DISSERTATION & RES
MTEN 633 - MACHINE LEARNING FOR ENGINEERS
MTSE 700B - MASTER'S PROJECT
MTEN 725 - INDEPENDENT STUDY I
PHEN 701C - MASTER'S THESIS
CHE 705 - INDEPENDENT STUDY I
MTEN 492 - RESRCH AND INDPENDENT STUDY II
MTEN 790A - DOCT DISSERTATION & RES
CHE 701C - MASTERS THESIS
MTEN 700B - MASTER'S PROJECT
MTEN 701B - MASTERS THESIS
CHE 792 - PRE-DOCTORAL RESEARCH
PHEN 725 - INDEPENDENT STUDY
CHE 492 - RESEARCH & INDEP STUDY
PHEN 701B - MASTER'S THESIS
CHE 491 - RESEARCH & INDEP STUDY
CHE 700B - MASTERS PROJECT
MTEN 491 - RESEARCH & INDEPENDENT STUDY I
MTEN 726 - INDEPENDENT STUDY II
MTEN 792 - PRE-DOCTORAL RESEARCH
CHE 706 - INDEPENDENT STUDY II
CHE 790A - DOCT DISSERTATION & RES
MTEN 633 - MACHINE LEARNING FOR ENGINEERS
MTSE 700B - MASTER'S PROJECT
MTEN 725 - INDEPENDENT STUDY I
PHEN 701C - MASTER'S THESIS
CHE 705 - INDEPENDENT STUDY I
MTEN 492 - RESRCH AND INDPENDENT STUDY II
MTEN 790A - DOCT DISSERTATION & RES
CHE 701C - MASTERS THESIS
MTEN 700B - MASTER'S PROJECT
MTEN 701B - MASTERS THESIS
Teaching Interests
Particle processing, characterization, experimental design, nanotechnology.
Past Courses
CHE 602: SELECTED TOPICS
CHE 702: ST:
CHE 702: ST: PROFESSIONAL DEVELOPMENT:WRITING & PRESENTATION
CHE 702: ST:DESIGN OF EXPERIMENTS
CHE 702: ST:MODULES NANO-PHARMACEUT II
CHE 702: ST:PARTICLE ENGINEERING FOR ADVANCED MATERIALS
CHE 714: MICROMECHANICS OF PART TECH PR
CHE 795: RESEARCH METHODS FOR DOCTORAL
MTEN 633: MACHINE LEARNING FOR CHEMICAL AND MATERIALS ENGINEERS
CHE 702: ST:
CHE 702: ST: PROFESSIONAL DEVELOPMENT:WRITING & PRESENTATION
CHE 702: ST:DESIGN OF EXPERIMENTS
CHE 702: ST:MODULES NANO-PHARMACEUT II
CHE 702: ST:PARTICLE ENGINEERING FOR ADVANCED MATERIALS
CHE 714: MICROMECHANICS OF PART TECH PR
CHE 795: RESEARCH METHODS FOR DOCTORAL
MTEN 633: MACHINE LEARNING FOR CHEMICAL AND MATERIALS ENGINEERS
Research Interests
His main research interests in Engineered Particulates include: synthesis of nano-particles and engineering of structured particle composites; modeling and development of novel techniques for dry particle coating, film-coated particles, granules and engineered particulates; nano-particle mixing, and nano-particle fluidization; powder flow and particle-particle interactions/cohesion; and DEM simulations.
Patents
System and Method for Fabrication of Uniform Polymer Films Containing Nano and Micro Particles via Continuous Drying Process
Methods for Superdisintegrant-Based Composite Particles for Dispersion and Dissolution of Active Pharmaceutical Agents
Systems and Methods for Superdisintegrant-Based Composite Particles for Dispersion and Dissolution of Agents
In Progress
PBM-DEM Simulations of Large-Scale Closed-Circuit Continuous Ball Milling of Cement Clinker
Developing advanced population balance models for cement milling processes via a PBM-DEM modeling framework. Funded by The Siam Research and Innovation Company/ SCG Thailand.
Developing advanced population balance models for cement milling processes via a PBM-DEM modeling framework. Funded by The Siam Research and Innovation Company/ SCG Thailand.
Journal Article
S.S. Kim, C. Castillo, M. Cheikhali, H. Darweesh, C. Kossor, R.N. Davé. 2023. “Enhanced blend uniformity and flowability of low drug loaded fine API blends via dry coating: The effect of mixing time and excipient size.” International Journal of Pharmaceutics, vol. 635.
S.S. Kim, A. Seetahal, N. Amores, C. Kossor, R.N. Davé. 2023. “Impact of Silica Dry Coprocessing with API and Blend Mixing Time on Blend Flowability and Drug Content Uniformity.” Journal of Pharmaceutical Sciences, vol. 112, no. 8, pp. 2124-2136.
Z. Lin, K. Zheng, M.A. Azad, R.N. Davé. 2023. “Preparation of Free-Flowing Spray-Dried Amorphous Composites Using Neusilin®.” AAPS PharmSciTech, vol. 24, no. 1.
K.T. Kunnath, S. Tripathi, S.S. Kim, L. Chen, K. Zheng, R.N. Davé. 2023. “Selection of Silica Type and Amount for Flowability Enhancements via Dry Coating: Contact Mechanics Based Predictive Approach.” Pharmaceutical Research.
Nontawat Muanpaopong, Rajesh N. Dave, Ecevit A. Bilgili. 2023. “Application of TUSSIM with a variable Tromp curve for predicting optimal operation of multi-compartment mills with various ball size distributions.” Advanced Powder Technology/Elsevier, vol. 34, no. 10, pp. 104171.
S.S. Kim, A. Seetahal, N. Amores, C. Kossor, R.N. Davé. 2023. “Impact of Silica Dry Coprocessing with API and Blend Mixing Time on Blend Flowability and Drug Content Uniformity.” Journal of Pharmaceutical Sciences, vol. 112, no. 8, pp. 2124-2136.
Z. Lin, K. Zheng, M.A. Azad, R.N. Davé. 2023. “Preparation of Free-Flowing Spray-Dried Amorphous Composites Using Neusilin®.” AAPS PharmSciTech, vol. 24, no. 1.
K.T. Kunnath, S. Tripathi, S.S. Kim, L. Chen, K. Zheng, R.N. Davé. 2023. “Selection of Silica Type and Amount for Flowability Enhancements via Dry Coating: Contact Mechanics Based Predictive Approach.” Pharmaceutical Research.
Nontawat Muanpaopong, Rajesh N. Dave, Ecevit A. Bilgili. 2023. “Application of TUSSIM with a variable Tromp curve for predicting optimal operation of multi-compartment mills with various ball size distributions.” Advanced Powder Technology/Elsevier, vol. 34, no. 10, pp. 104171.
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Other
“Special issue of the 8th World Congress on Particle Technology (WCPT8): Applications of particle technology for pharmaceuticals”
Advanced Powder Technology, December 2018.
“Discrete element method simulation of cohesive particles mixing under magnetically assisted impaction”
Powder Technology, July (3rd Quarter/Summer) 2014.
“Dispersion of fine and ultrafine powders through surface modification and rapid expansion”
Chemical Engineering Science, 2013.
“Dry coating of micronized API powders for improved dissolution of directly compacted tablets with high drug loading”
International Journal of Pharmaceutics, 2013.
“Dynamic simulation of particle packing influenced by size, aspect ratio and surface energy”
Granular Matter, 2013.
Advanced Powder Technology, December 2018.
“Discrete element method simulation of cohesive particles mixing under magnetically assisted impaction”
Powder Technology, July (3rd Quarter/Summer) 2014.
“Dispersion of fine and ultrafine powders through surface modification and rapid expansion”
Chemical Engineering Science, 2013.
“Dry coating of micronized API powders for improved dissolution of directly compacted tablets with high drug loading”
International Journal of Pharmaceutics, 2013.
“Dynamic simulation of particle packing influenced by size, aspect ratio and surface energy”
Granular Matter, 2013.
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Conference Proceeding
“Dissolution of Poorly Soluble Drug Nanoparticles from Edible Polymer Stripfilms”
Controlled Release Society, July (3rd Quarter/Summer) 2014.
“Translating Research Experience into Classroom Practice: An RET Project”
Proceedings of the 2011 American Society for Engineering Education Annual Conference, June 2011.
“Connecting high school Science with better medicines: A RET Outreach of the NSF ERC-SOPS”
National Science Foundation, February 2010.
“On laboratory development for a curriculum in particle technology”
ASEE Annual Meeting, 1997.
“Particle technology research at NJIT”
ASEE Annual Meeting, 1995.
Controlled Release Society, July (3rd Quarter/Summer) 2014.
“Translating Research Experience into Classroom Practice: An RET Project”
Proceedings of the 2011 American Society for Engineering Education Annual Conference, June 2011.
“Connecting high school Science with better medicines: A RET Outreach of the NSF ERC-SOPS”
National Science Foundation, February 2010.
“On laboratory development for a curriculum in particle technology”
ASEE Annual Meeting, 1997.
“Particle technology research at NJIT”
ASEE Annual Meeting, 1995.