I conduct research on human brain connectivity and brain network organizations using neuroimaging techniques such as functional magnetic resonance imaging (fMRI). I develop computational models to measure brain connectivity in different mental conditions, such as during cognitive tasks and watching movies. I am also interested in applying the methods to understand brain development and aging, as well as mental conditions such as autism spectrum disorder (ASD).
Education
Ph.D.
Awards & Honors
2018 Top reviewers for Neuroscience And Behavior, Publons
Brain imaging fMRI data analysis Brain connectivity analysis
Research Interests
Brain connectivity and brain network organizations. Task connectome. Functional neuroimaging.
In Progress
Functional brain developments during movie watching and resting-state in autism spectrum disorder NIH funded research project to study brain functional developments in typically developing children and children with autism spectrum disorder. In this project, we will analyze a large-scale open-access fMRI dataset where the participants underwent fMRI using movie watching and resting-state paradigms.
Journal Article
Wonbum Sohn, Xin Di, Zhen Liang, Zhiguo Zhang, Bharat B Biswal. 2024. "Explorations of using a convolutional neural network to understand brain activations during movie watching." Psychoradiology, vol. 4.
Xin Di, Bharat Biswal. 2022. "Estimations of the weather effects on brain functions using functional MRI: A cautionary note." Human Brain Mapping.
Xin Di, Bharat Biswal, . 2022. "Principal component analysis reveals multiple consistent responses to naturalistic stimuli in children and adults." Human Brain Mapping.
Xin Di, Z Zhang, Bharat Biswal. 2021. "Understanding psychophysiological interaction and its relations to beta series correlation.." Brain imaging and behavior, vol. 15, pp. 958–973.
Xin Di, H Zhang, Bharat Biswal. 2020. "Anterior cingulate cortex differently modulates frontoparietal functional connectivity between resting-state and working memory tasks.." Human brain mapping, vol. 41, no. 7, pp. 1797-1805.
Xin Di, Bharat Biswal. 2020. "Intersubject consistent dynamic connectivity during natural vision revealed by functional MRI.." NeuroImage, pp. 116698.
Xin Di, M Wölfer, M Amend, H Wehrl, T M Ionescu, B J Pichler, Bharat Biswal. 2019. "Interregional causal influences of brain metabolic activity reveal the spread of aging effects during normal aging.." Human brain mapping, vol. 40, no. 16, pp. 4657-4668.
Xin Di, Bharat Biswal. 2019. "Toward Task Connectomics: Examining Whole-Brain Task Modulated Connectivity in Different Task Domains.." Cerebral cortex (New York, N.Y. : 1991), vol. 29, no. 4, pp. 1572-1583.
Xin Di, A Azeez, Xiaobo Li, E Haque, Bharat Biswal. 2018. "Disrupted focal white matter integrity in autism spectrum disorder: A voxel-based meta-analysis of diffusion tensor imaging studies.." Progress in neuro-psychopharmacology & biological psychiatry, vol. 82, pp. 242-248.
Xin Di, S Gohel, A Thielcke, H F Wehrl, Bharat Biswal. 2017. "Do all roads lead to Rome? A comparison of brain networks derived from inter-subject volumetric and metabolic covariance and moment-to-moment hemodynamic correlations in old individuals.." Brain structure & function, vol. 222, no. 8, pp. 3833-3845.
Xin Di, Bharat Biswal. 2017. "Psychophysiological Interactions in a Visual Checkerboard Task: Reproducibility, Reliability, and the Effects of Deconvolution.." Frontiers in neuroscience, vol. 11, pp. 573.
Xin Di, R C Reynolds, Bharat Biswal. 2017. "Imperfect (de)convolution may introduce spurious psychophysiological interactions and how to avoid it.." Human brain mapping, vol. 38, no. 4, pp. 1723-1740.
Xin Di, J Huang, Bharat Biswal. 2017. "Task modulated brain connectivity of the amygdala: a meta-analysis of psychophysiological interactions.." Brain structure & function, vol. 222, no. 1, pp. 619-634.
Xin Di, Bharat Biswal. 2016. "Similarly Expanded Bilateral Temporal Lobe Volumes in Female and Male Children With Autism Spectrum Disorder.." Biological psychiatry. Cognitive neuroscience and neuroimaging, vol. 1, no. 2, pp. 178-185.
Xin Di, Bharat Biswal. 2015. "Characterizations of resting-state modulatory interactions in the human brain.." Journal of neurophysiology, vol. 114, no. 5, pp. 2785-96.
Xin Di, Z Fu, S C Chan, Y S Hung, Bharat Biswal, Z Zhang. 2015. "Task-related functional connectivity dynamics in a block-designed visual experiment.." Frontiers in human neuroscience, vol. 9, pp. 543.
Xin Di, E H Kim, P Chen, Bharat Biswal. 2014. "Lateralized resting-state functional connectivity in the task-positive and task-negative networks.." Brain connectivity, vol. 4, no. 9, pp. 641-8.
Xin Di, Bharat Biswal. 2014. "Modulatory interactions between the default mode network and task positive networks in resting-state.." PeerJ, vol. 2, pp. e367.
Xin Di, Bharat Biswal. 2014. "Identifying the default mode network structure using dynamic causal modeling on resting-state functional magnetic resonance imaging.." NeuroImage, vol. 86, pp. 53-9.
Xin Di, B Rypma, Bharat Biswal. 2014. "Correspondence of executive function related functional and anatomical alterations in aging brain.." Progress in neuro-psychopharmacology & biological psychiatry, vol. 48, pp. 41-50.
Xin Di, S Gohel, E H Kim, Bharat Biswal. 2013. "Task vs. rest-different network configurations between the coactivation and the resting-state brain networks.." Frontiers in human neuroscience, vol. 7, pp. 493.
Xin Di, Bharat Biswal. 2013. "Modulatory interactions of resting-state brain functional connectivity.." PloS one, vol. 8, no. 8, pp. e71163.
Xin Di, E H Kim, C C Huang, S J Tsai, C P Lin, Bharat Biswal. 2013. "The influence of the amplitude of low-frequency fluctuations on resting-state functional connectivity.." Frontiers in human neuroscience, vol. 7, pp. 118.
Xin Di, S S Kannurpatti, B Rypma, Bharat Biswal. 2013. "Calibrating BOLD fMRI activations with neurovascular and anatomical constraints.." Cerebral cortex (New York, N.Y. : 1991), vol. 23, no. 2, pp. 255-63.
Xin Di, S Zhu, H Jin, P Wang, Z Ye, K Zhou, Y Zhuo, H Rao. 2012. "Altered resting brain function and structure in professional badminton players.." Brain connectivity, vol. 2, no. 4, pp. 225-33.
Xin Di, Bharat Biswal. 2012. "Metabolic brain covariant networks as revealed by FDG-PET with reference to resting-state fMRI networks.." Brain connectivity, vol. 2, no. 5, pp. 275-83.
C Qian, Xin Di. 2011. "Phase or amplitude? The relationship between ongoing and evoked neural activity.." The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 31, no. 29, pp. 10425-6.
Xin Di, R C Chan, Q Y Gong. 2009. "White matter reduction in patients with schizophrenia as revealed by voxel-based morphometry: an activation likelihood estimation meta-analysis.." Progress in neuro-psychopharmacology & biological psychiatry, vol. 33, no. 8, pp. 1390-4.