Jorge Golowasch
Jorge Golowasch
Professor and Research Director, Biological Sciences, Biological Sciences
CKB 420F
About Me
I was born and grew up in Santiago, Chile. My college education was at the Faculty of Sciences, Universidad de Chile (major in Biology, concentration in Neuroscience). I moved to the US in 1986 to do a PhD at Brandeis University, then did post-docs at the Ecole Normale Superieure (Paris, France), U. Kaiserslautern (Germany) and at HHMI (Mass Gen Hospital, Boston).
Education
Ph.D.; Brandeis University; Biophysics; 1991
B.S.; Faculty of Sciences, Universida de Chile; Biology; 1984
B.S.; Faculty of Sciences, Universida de Chile; Biology; 1984
2025 Spring Courses
BIOL 700B - MASTER'S PROJECT
BIOL 701C - MASTER'S THESIS
BIOL 790A - DOCT DISSERTATION & RESRCH
BIOL 790D - DOCT DISSERTATION & RESRCH
BIOL 792C - PRE-DOCTORAL RESEARCH
BIOL 491 - SENIOR PROJECT
BIOL 492 - RESEARCH & INDEPENDENT STUDY
BIOL 790E - DOCTORAL DISSERTATION
BIOL 725 - INDEPENDENT STUDY I
BIOL 726 - INDEPENDENT STUDY II
BIOL 498 - ST: GLIA, THE NEURON'S FORGOTTEN SIBLING
BIOL 790C - DOCTORAL DISSERTN & RESRCH
BIOL 792B - PRE-DOCTORAL RESEARCH
BIOL 698 - ST: GLIA, THE NEURON'S FORGOTTEN SIBLING
BIOL 790B - DOCT DISSERTATION & RESRCH
BIOL 701B - MASTER'S THESIS
BIOL 701C - MASTER'S THESIS
BIOL 790A - DOCT DISSERTATION & RESRCH
BIOL 790D - DOCT DISSERTATION & RESRCH
BIOL 792C - PRE-DOCTORAL RESEARCH
BIOL 491 - SENIOR PROJECT
BIOL 492 - RESEARCH & INDEPENDENT STUDY
BIOL 790E - DOCTORAL DISSERTATION
BIOL 725 - INDEPENDENT STUDY I
BIOL 726 - INDEPENDENT STUDY II
BIOL 498 - ST: GLIA, THE NEURON'S FORGOTTEN SIBLING
BIOL 790C - DOCTORAL DISSERTN & RESRCH
BIOL 792B - PRE-DOCTORAL RESEARCH
BIOL 698 - ST: GLIA, THE NEURON'S FORGOTTEN SIBLING
BIOL 790B - DOCT DISSERTATION & RESRCH
BIOL 701B - MASTER'S THESIS
Teaching Interests
Neuroscience, Computational Neuroscience/Biology, Cell Biology, Critical Thinking, special topics in neuroscience
Past Courses
BIOL 315: PRINCIPLES OF NEUROBIOLOGY
BIOL 341: INTRO TO NEUROPHYSIOLOGY
BIOL 405: CELL PHYSIOLOGY AND IMAGING
BIOL 447: CELLULAR & SYSTEM NEUR-HONORS
BIOL 447: CELLULAR&SYSTEMS NEUROSC-HON
BIOL 447: CELLULAR&SYSTEMS NEUROSCIENCE
BIOL 447: SYSTEMS NEUROBIOLOGY
BIOL 498: ST: THE NEURON'S FORGOTTEN SIBLING
BIOL 630: CRITICAL THINKING FOR LIFE SCI
BIOL 641: SYSTEMS NEUROSCIENCE
BIOL 698: INTRO TO NEUROPHYSIOLOGY
BIOL 698: ST:
BIOL 698: ST: THE NEURON'S FORGOTTEN SIBLING
BIOL 698: ST:NEUROSCIENCE
R120 524: CELL MOLEC DEV
BIOL 341: INTRO TO NEUROPHYSIOLOGY
BIOL 405: CELL PHYSIOLOGY AND IMAGING
BIOL 447: CELLULAR & SYSTEM NEUR-HONORS
BIOL 447: CELLULAR&SYSTEMS NEUROSC-HON
BIOL 447: CELLULAR&SYSTEMS NEUROSCIENCE
BIOL 447: SYSTEMS NEUROBIOLOGY
BIOL 498: ST: THE NEURON'S FORGOTTEN SIBLING
BIOL 630: CRITICAL THINKING FOR LIFE SCI
BIOL 641: SYSTEMS NEUROSCIENCE
BIOL 698: INTRO TO NEUROPHYSIOLOGY
BIOL 698: ST:
BIOL 698: ST: THE NEURON'S FORGOTTEN SIBLING
BIOL 698: ST:NEUROSCIENCE
R120 524: CELL MOLEC DEV
Research Interests
Neuroscience: mechanisms that control the stability of neuronal activity, analytical and quantitative analysis of electrical properties of neurons and networks, neuromodulation, circadian activity, glia-neuron interactions.
Journal Article
Anna C Schneider, David Fox, Omar Itani, Jorge P. Golowasch, Dirk M. Bucher, Farzan Nadim. 2021. “Frequency-Dependent Action of Neuromodulation.” eNeuro , vol. 8, no. 6.
Trinh Tran, Cagri T Unal, Laszlo Zaborszky, Alfredo Kirkwood, Horacio G. Rotstein, Jorge P. Golowasch. 2019. “Ionic current correlations are ubiquitous across phyla.” Scientific Reports, vol. 9, pp. 1687.
Jorge P. Golowasch, Amitabha K. Bose, Y. Guan, D. Salloum, A. Roeser, Farzan Nadim. 2017. “A balance of outward and linear inward ionic currents is required for generation of slow-wave oscillations.” Journal of Neurophysiology, vol. 118, pp. 1092-1104.
Jorge P. Golowasch. 2017. “Activation mechanism of a neuromodulator-gated pacemaker ionic current..” J. Neurophysiology, vol. 118, pp. 595–609.
Horacio G. Rotstein, Motolani Olarinre, Jorge P. Golowasch. 2016. “Dynamic compensation mechanism give rise to period and duty cycle level sets in oscillatory neuronal models.” Journal of Neurophysiology, vol. Online First.
Trinh Tran, Cagri T Unal, Laszlo Zaborszky, Alfredo Kirkwood, Horacio G. Rotstein, Jorge P. Golowasch. 2019. “Ionic current correlations are ubiquitous across phyla.” Scientific Reports, vol. 9, pp. 1687.
Jorge P. Golowasch, Amitabha K. Bose, Y. Guan, D. Salloum, A. Roeser, Farzan Nadim. 2017. “A balance of outward and linear inward ionic currents is required for generation of slow-wave oscillations.” Journal of Neurophysiology, vol. 118, pp. 1092-1104.
Jorge P. Golowasch. 2017. “Activation mechanism of a neuromodulator-gated pacemaker ionic current..” J. Neurophysiology, vol. 118, pp. 595–609.
Horacio G. Rotstein, Motolani Olarinre, Jorge P. Golowasch. 2016. “Dynamic compensation mechanism give rise to period and duty cycle level sets in oscillatory neuronal models.” Journal of Neurophysiology, vol. Online First.
SHOW MORE
Amitabha K. Bose, Jorge P. Golowasch, Yinzheng Guan, Farzan Nadim. 2014. “The role of linear and voltage-dependent ionic currents in the generation of slow wave oscillations.” Journal of Computational Neuroscience, vol. 37, no. 2, pp. 229-242.
Jorge P. Golowasch. 2014. “Mechanisms underlying nervous system plasticity and stability. .” Bioscience, vol. 64, no. 7, pp. 570-580.
Shunbig Zhao, Jorge P. Golowasch. 2012. “Ionic Current Correlations Underlie the Global Tuning of Large Numbers of Neuronal Activity Attributes.” Journal of Neuroscience, vol. 32, no. 39, pp. 13380-13388.
Cagri T Unal, Jorge P. Golowasch, Laszlo Zaborszky. 2012. “Adult mouse basal forebrain harbors two distinct cholinergic populations defined by their electrophysiology.” Frontiers in behavioral Neuroscience, vol. 6, no. 21, pp. 1-14.
Simone Temporal, Mohati Desai, Olga Khorkova, Gladis Varghese, Aihua Dai, David Schulz, Jorge P. Golowasch. 2011. “Neuromodulation independently determines correlated channel expression and conductance levels in motor neurons of the stomatogastric ganglion.” Journal of Neurophysiology, vol. In press.
Yili Zhang, Jorge P. Golowasch. 2011. “Recovery of rhythmic activity in a central pattern generator: analysis of the role of neuromodulator and activity-dependent mechanisms.” Journal of Computational Neuroscience, vol. In press.
Shunbing Zhao, Jorge P. Golowasch, Farzan Nadim. 2010. “Pacemaker neuron and network oscillations depend on a neuromodulator-regulated linear current.” Frontiers in Behavioral Neuroscience, vol. 4, no. 21.
Farzan Nadim, Jorge P. Golowasch, Gladis Thomas, Adam Taylor, Christopher Khalil, Arlene Pineda, Arif Patel. 2009. “Membrane capacitance measurements revisited: dependence of capacitance value on measurement method in non-isopotential neurons.” Journal of Neurophysiology, vol. 102, pp. 2161-2175.
Yili Zhang, Khorkova Olga, Rodriguez Rosa, Jorge P. Golowasch. 2008. “Activity and Neuromodulatory Input Contribute to the Recovery of Rhythmic Output After Decentralization in a Central Pattern Generator.” Journal of Neurophysiology, vol. 101, pp. 372-386.
Juliane Gansert, Jorge P. Golowasch, Farzan Nadim. 2007. “Sustained rhythmic activity in gap- neurons depends on the diameter of coupled dendrites.” Journal of Neurophysiology, vol. 98, pp. 3450-3460.
Jorge P. Golowasch. 2014. “Mechanisms underlying nervous system plasticity and stability. .” Bioscience, vol. 64, no. 7, pp. 570-580.
Shunbig Zhao, Jorge P. Golowasch. 2012. “Ionic Current Correlations Underlie the Global Tuning of Large Numbers of Neuronal Activity Attributes.” Journal of Neuroscience, vol. 32, no. 39, pp. 13380-13388.
Cagri T Unal, Jorge P. Golowasch, Laszlo Zaborszky. 2012. “Adult mouse basal forebrain harbors two distinct cholinergic populations defined by their electrophysiology.” Frontiers in behavioral Neuroscience, vol. 6, no. 21, pp. 1-14.
Simone Temporal, Mohati Desai, Olga Khorkova, Gladis Varghese, Aihua Dai, David Schulz, Jorge P. Golowasch. 2011. “Neuromodulation independently determines correlated channel expression and conductance levels in motor neurons of the stomatogastric ganglion.” Journal of Neurophysiology, vol. In press.
Yili Zhang, Jorge P. Golowasch. 2011. “Recovery of rhythmic activity in a central pattern generator: analysis of the role of neuromodulator and activity-dependent mechanisms.” Journal of Computational Neuroscience, vol. In press.
Shunbing Zhao, Jorge P. Golowasch, Farzan Nadim. 2010. “Pacemaker neuron and network oscillations depend on a neuromodulator-regulated linear current.” Frontiers in Behavioral Neuroscience, vol. 4, no. 21.
Farzan Nadim, Jorge P. Golowasch, Gladis Thomas, Adam Taylor, Christopher Khalil, Arlene Pineda, Arif Patel. 2009. “Membrane capacitance measurements revisited: dependence of capacitance value on measurement method in non-isopotential neurons.” Journal of Neurophysiology, vol. 102, pp. 2161-2175.
Yili Zhang, Khorkova Olga, Rodriguez Rosa, Jorge P. Golowasch. 2008. “Activity and Neuromodulatory Input Contribute to the Recovery of Rhythmic Output After Decentralization in a Central Pattern Generator.” Journal of Neurophysiology, vol. 101, pp. 372-386.
Juliane Gansert, Jorge P. Golowasch, Farzan Nadim. 2007. “Sustained rhythmic activity in gap- neurons depends on the diameter of coupled dendrites.” Journal of Neurophysiology, vol. 98, pp. 3450-3460.
COLLAPSE
Chapter
Farzan Nadim, Xinping Li, Michael Gray, Jorge P. Golowasch. 2017. “The Role of Electrical Coupling in Rhythm Generation in Small Networks.” pp. 51-78. London, United Kingdom: Academic Press, 2017.
Dirk M. Bucher, Gal Haspel, Jorge P. Golowasch, Farzan Nadim. 2015. “Central Pattern Generators.” pp. 1-12. Chichester, : eLS, John Wiley & Sons, 2015.
Jorge P. Golowasch, Farzan Nadim. 2014. “Capacitance, Membrane.” In Jaeger, Dieter; Jung, Ranu (Eds.), pp. 1-5. New York, : Springer, 2014.
Jorge P. Golowasch. 2014. “Stability and Homeostasis in Small Network Central Pattern Generators.” In Jaeger, Dieter; Jung, Ranu (Eds.), pp. 2858-2864. New York, : Springer, 2014.
Dirk M. Bucher, Gal Haspel, Jorge P. Golowasch, Farzan Nadim. 2015. “Central Pattern Generators.” pp. 1-12. Chichester, : eLS, John Wiley & Sons, 2015.
Jorge P. Golowasch, Farzan Nadim. 2014. “Capacitance, Membrane.” In Jaeger, Dieter; Jung, Ranu (Eds.), pp. 1-5. New York, : Springer, 2014.
Jorge P. Golowasch. 2014. “Stability and Homeostasis in Small Network Central Pattern Generators.” In Jaeger, Dieter; Jung, Ranu (Eds.), pp. 2858-2864. New York, : Springer, 2014.
Technical Report
“Single-Neuron Gene Expression Analysis Using the Maxwell® 16 LEV System in the Neural Systems and Behavior Course”
Promega Corporation Web site, January (1st Quarter/Winter) 2014.
Promega Corporation Web site, January (1st Quarter/Winter) 2014.
Other
“Dynamic Neural Networks: The Stomatogastric System”
October (4th Quarter/Autumn) 2012.
“Dynamic Neural Networks: The Stomatogastric System”
November 2011.
“Dynamic Neural Networks: The Stomatogastric System”
November 2010.
“Dynamic Neural Networks: The Stomatogastric System”
October (4th Quarter/Autumn) 2009.
October (4th Quarter/Autumn) 2012.
“Dynamic Neural Networks: The Stomatogastric System”
November 2011.
“Dynamic Neural Networks: The Stomatogastric System”
November 2010.
“Dynamic Neural Networks: The Stomatogastric System”
October (4th Quarter/Autumn) 2009.
Conference Proceeding
“Approximating the phase response curves of square wave bursting neurons.”
BMC Neuroscience, July (3rd Quarter/Summer) 2008.
BMC Neuroscience, July (3rd Quarter/Summer) 2008.